Estudio y desarrollo de materiales supramoleculares para su aplicación en la nanomedicina.

Síntesis de estructuras supramoleculares dendríticas para aplicaciones biomédicas

Estudio de la Nanotecnología y la Nanomedicina a través de Vigilancia Tecnológica

Nanopartículas magnéticas de óxido de hierro y su aplicación en nanomedicina

Publicaciones

Rojas-Aguirre Y*., Rizo J., Martínez-Aguilera M, Rodríguez-Hernández A., Díaz-Bello B., Vázquez-Victorio G., Domínguez-Castro H., Mendoza-Cruz R., Betancourt I., Ortega-Galindo S, Guadarrama P* (2024). Facet-dependent Magnetic Properties of Magnetite Nanoparticles Coated with Dodecylamine and Their Biological Effect in HepG2 cell line. Journal of Materials Sciences 59 (1), 991-1009 https://doi.org/10.1007/s10853-023-09235-3 FI 3.5

Morales-Salazar I., Garduño-Albino C. E., Montes-Enríquez F. P., Gutiérrez-Carrillo A., Rojas-Aguirre Y., Estrada-Toledo N. V., Sandoval-Basilio J., Alcaraz-Estrada S.,* Díaz-Cervantes E.,* González-Zamora E., Islas-Jácome A.* (2024). In Vitro and In Silico studies of bis-furyl-pyrrolo[3,4-b]pyridin-5-ones on Dengue virus replicon. Journal of the Mexican Chemical Society, 68 (1), 170-183 https://doi.org/10.29356/jmcs.v68i1.2103 FI 1.5

Morales-Salazar I., Montes-Enríquez F. P., Garduño-Albino C. E., García-Sánchez M. A., Ibarra I. A., Rojas-Aguirre Y., García-Hernández M. E., Sarmiento-Silva R.E., Alcaraz-Estrada S. L*., Díaz-Cervantes E*., González-Zamora E*., Islas-Jácome A* (2023). Synthesis of bis-furyl-pyrrolo[3,4-b] pyridin-5-ones via Ugi–Zhu reaction and in vitro activity assays against human SARS-CoV-2 and in silico studies on its main proteins. RSC Medicinal Chemistry 14 (1) 154-165 https://doi.org/10.1039/D2MD00350C FI 3.470

Rincón-López J., Martínez-Aguilera M., Guadarrama P., Juarez-Moreno K., Rojas-Aguirre Y* (2022). Exploring in vitro biological cellular responses of pegylated β-cyclodextrins. Molecules 27 (9) 3026 https://doi.org/10.3390/molecules27093026 FI 4.412 FI 4.412

Rincón-López J., Ramírez-Rodríguez N., Luviano S. A., Costas M., López-Cervantes J. L., García-Figueroa A. A., Domínguez H., Mendoza-Cruz R., Guadarrama P., López-Morales S., Rojas-Aguirre Y* (2022). Experimental and theoretical studies of pegylated-β-cyclodextrin: A step forward to understand its tunable self-aggregation abilities. Journal of Drug Delivery Science and Technology 67 (1), 1-11 https://doi.org/10.1016/j.jddst.2021.102975 FI 3.981

Cabrera-Quiñones N., López-Méndez L., Ramos E., Rojas-Aguirre Y., and Guadarrama P* (2022). Mono-dendronized β‑Cyclodextrin derivatives as multitasking containers for curcumin. Impacting its solubility, loading, and tautomeric form. The Journal of Physical Chemistry B, 126 (1), 1529-1538 https://doi.org/10.1021/acs.jpcb.1c09811 FI 2.991

Rincón-López J., Almanza-Arjona Y., Riascos P. A. *, Rojas-Aguirre Y* (2021). When cyclodextrins met data science: unveiling their pharmaceutical applications through network science and text-mining. Pharmaceutics, 13(8), 1297 https://doi.org/10.3390/pharmaceutics13081297 FI 6.321

Rincón-López J., Almanza-Arjona Y., Riascos P. A.*., Rojas-Aguirre Y* (2021). Technological evolution of cyclodextrins in the pharmaceutical field. Journal of Drug Delivery Science and Technology 61 (1), 1-14 https://doi.org/10.1016/j.jddst.2020.102156 FI 3.981

López-Méndez L., Cuéllar-Ramírez E., Cabrera-Quiñones N., Rojas-Aguirre Y., and Guadarrama P.* (2020). Convergent click synthesis of macromolecular dendritic β-cyclodextrin derivatives as non-conventional drug carriers: Albendazole as guest model. International Journal of Biological Macromolecules 164 (1), 1704-1714 https://doi.org/10.1016/j.ijbiomac.2020.08.018. FI 6.9.53

López-Méndez, L., Rojas-Aguirre, Y., Vázquez-Lima, H., Cassani, J., Enríquez, R.G., Rojo-Domínguez A., Guadarrama P.* (2020). On the conformational search of a βCD dendritic derivative: NMR and theoretical calculations working together reveal a donut-like amphiphilic structure. Journal of Molecular Structure 1204, https://doi.org/10.1016/j.molstruc.2019.127535. FI 3.196

Rojas-Aguirre Y*., Torres-Mena M. A., López-Méndez J. L., Alcaraz-Estrada S. L., Guadarrama P., Urucha-Ortíz J. M. (2019). PEGylated β-cyclodextrins: click synthesis and in vitro biological insights. Carbohydrate Polymers 223 (1), 1-9. https://doi.org/10.1016/j.carbpol.2019.115113. FI 9.381

Segura-Olvera D., García-González A. N., Morales-Salazar I., Islas-Jácome A., Rojas-Aguirre Y., Ibarra A. I., Díaz-Cervantes E*., Alcaraz-Estrada S. E*., González-Zamora E*. (2019). Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Multicomponent Reactions and In Vitro–In Silico Studies Against SiHa, HeLa, and CaSki Human Cervical Carcinoma Cell Lines. Molecules 24 (14), 2648- 2663.
https://doi.org/10.3390/molecules24142648. FI 4.412

González-Méndez I., Solano J. D., Porcu P., Ruiu A., Rojas-Aguirre Y*., Rivera E*. (2019). Optimized synthesis, characterization and in vitro systematic evaluation of adamantane-doxorubicin prodrugs sensitive to pH in breast cancer cells. Journal of Molecular Structure 1177 (5), 143-151. https://doi.org/10.1016/j.molstruc.2018.09.044. FI 3.196

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx