Contacto
Campos de conocimiento
Inmunología
Neurobiología
Líneas de investigación
Neuroinflamación y su modulación por silimarina y silibina en enfermedades neurodegenerativas.
Efecto de la inflamación sistémica por obesidad en la neuroinflamación.
Efecto hipoglicemiante de la silimarina en cultivo de adipocitos y en animales obesos.
Publicaciones
1. Medrano-Hernández A, Neri-Nani G, Rodriguez-Violante M, Crucker-Colin R, Chavarría A. Inefficacy of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease Patients with Levodopa-Induced Dyskinesias: Results from a Pilot Study. En prensa en Biomedicines. (factor de impacto 3.9).
2. Balcazar-Ochoa LG, Ángeles-López GE, Chavarría A, Ramírez-Carreto RJ, González-Hernández A, Guzmán-Ruiz MA, Segovia-Mendoza M, Ochoa-Aguilar A, Ventura-Martínez R. Clavulanic acid prevents paclitaxel-induced neuropathic pain through a systemic and central anti-inflammatory effect in mice. Neurotherapeutics. 2025; 22(2):e00522. (factor de impacto 5.6).
3. Rodríguez-Cortés YM, Ramírez-Carreto RJ, Rodríguez-Barrena JI, Salazar-Castro M, Chavarría A. Silymarin administration after cerebral ischemia improves survival of obese mice by increasing cortical BDNF and IGF1 levels. Frontiers in Aging Neuroscience. 2024; 16:1484946. (factor de impacto 4.1).
4. Guzmán-Ruíz MA, Guerrero Vargas NN, Ramírez-Carreto RJ, González-Orozco JC, Torres-Hernández BA, Valle-Rodríguez M, Guevara-Guzmán R, Chavarría A. Microglia in physiological conditions and the importance of understanding their homeostatic functions in the arcuate nucleus. Frontiers in Immunology. 2024, 15:1392077. (2 citas, factor de impacto 5.7).
5. Reyes-Soto CY, Ramírez-Carreto RJ, Ortíz-Alegría LB, Silva-Palacios A, Zazueta C, Galván-Arzate S, Karasu Ç, Túnez I, Tinkov AA, Aschner M, López-Goerne T, Chavarría A, Santamaría A. S-allyl-cysteine triggers cytotoxic events in rat glioblastoma RG2 and C6 cells and improves the effect of temozolomide through the regulation of oxidative responses. Discover Oncology. 2024; 15(1):272. (factor de impacto 2.8)
6. Butanda-Nuñez A, Rodríguez-Cortés O, Ramos-Martínez E, Cerbón MA, Escobedo G, Chavarría A. Silybin restores glucose uptake after tumor necrosis factor alpha and lipopolysaccharide stimulation in 3T3-L1 adipocytes. Adipocyte. 2024; 13(1): 2374062. (2 citas, factor de impacto 3.5)
7. Duarte-Campos JF, Vázquez-Moreno CN, Martínez-Marcial M, Chavarría A, Ramírez-Carreto RJ, Velasco Velázquez MA, De La Fuente-Granada M, González-Arenas A. Changes in neuroinflammatory markers and microglial density in the hippocampus and prefrontal cortex of the C58/J mouse model of autism. Eur J Neurosci. 2024; 59(1):154–173. (5 citas, factor de impacto 2.7)
8. Balcazar-Ochoa LG, Ventura-Martínez R, Ángeles-López GE, Gómez-Acevedo C, Carrasco OF, Sampieri-Cabrera R, Chavarría A, González-Hernández A. Clavulanic Acid and its Potential Therapeutic Effects on the Central Nervous System. Archives of Medical Research. 2024; 55(1):102916. (4 citas, factor de impacto 4.7)
9. Ramírez-Carreto RJ, Zaldívar-Machorro VJ, Pérez-Ramírez DJ, Rodríguez-López BE, Meza C, García E, Santamaría A, Chavarría A. Oral Administration of Silybin Protects Against MPTP-Induced Neurotoxicity by Reducing Pro-inflammatory Cytokines and Preserving BDNF Levels in Mice. Molecular Neurobiology. 2023; 60(12):6774-6788. (7 citas, factor de impacto 4.6).
10. Ramírez-Carreto RJ, Rodríguez-Cortés YM, Torres-Guerrero H, Chavarría A. Possible Implications of Obesity-Primed Microglia that Could Contribute to Stroke-Associated Damage. Cellular and Molecular Neurobiology. 2023; 43(6):2473-2490. (5 citas, factor de impacto 3.6).
11. Salas-Venegas V, Santín-Márquez R, Ramírez-Carreto RJ, Rodríguez-Cortés YM, Cano-Martínez A, Luna-López A, Chavarría A, Konigsberg M, López-Díazguerrero NE. Chronic consumption of a hypercaloric diet increases neuroinflammation and brain senescence, promoting cognitive decline in middle-aged female Wistar rats. Frontiers in Aging Neuroscience. 2023; 15:1162747. (7 citas, factor de impacto 4.1)
12. Torres-Guerrero Haydée, Ramírez-Carreto Ricardo Jair, Rodríguez-Cortés Yesica, Chavarría Anahí. La alteración hipotálamica en la obesidad: neuroinflamación y disfunción metabólica. Revista Mexicana en Trastornos Alimentarios, Julio-Diciembre 2023, Vol. 13, Núm 2, 170-186. (Indizada en Conacyt y Latinindex)
13. Torres-Guerrero Haydée, Ramírez-Carreto Ricardo Jair, Rodríguez-Cortés Yesica, Chavarría Anahí. La alteración hipotálamica en la obesidad: hormonas y circuitos neuronales. Revista de Medicina e Investigación UAEMéx, Enero-Junio 2023 Vol. 11 Núm. 1, 56-65. (Indizada en Conacyt y Latinindex)
14. García E, García-De-La-Rosa LA, Veloz-Castillo MF, Méndez-Rojas MA, Chavarría A. Preservation of Dopamine Levels in a Mouse Model of Parkinson's Disease by Carboxymethylated Silica and Starch Nanoparticles Coupled to Silybin. ChemistrySelect. 2023; 8(3):e202204332. (1 cita, factor de im pacto 1.9)
15. Guzmán-Ruiz MA, Guerrero-Vargas NN, Lagunes-Cruz A, González-González S, García-Aviles JE, Hurtado-Alvarado G, Mendez-Hernández R, Chavarría-Krauser A, Morin JP, Arriaga-Avila V, Buijs RM, Guevara-Guzmán R. Circadian modulation of microglial physiological processes and immune responses. Glia. 2023; 71(2):155-167. (9 citas, factor de impacto 5.4)
16. Salas-Venegas V, Flores-Torres RP, Rodríguez-Cortés YM, Rodríguez-Retana D, Ramírez-Carreto RJ, Concepción-Carrillo LE, Pérez-Flores LJ, Alarcón-Aguilar A, López-Díazguerrero NE, Gómez-González B, Chavarría A, Konigsberg M. The Obese Brain: Mechanisms of Systemic and Local Inflammation, and Interventions to Reverse the Cognitive Deficit. Frontiers in Integrative Neuroscience. 2022 Mar 29;16:798995. (50 citas; factor de impacto 2.6)
17. Jiménez-González A, Gómez-Acevedo C, Ochoa-Aguilar A, Chavarría A. The Role of Glia in Addiction: Dopamine as a Modulator of Glial Responses in Addiction. Cellular and Molecular Neurobiology. 2022; 42(7):2109-2120 (8 citas; factor de impacto 3.6)
18. Reyes-Soto CY, Rangel-López E, Galván-Arzate S, Colín-González AL, Silva-Palacios A, Zazueta C, Pedraza-Chaverri J, Ramírez J, Chavarría A, Túnez I, Ke T, Aschner M, Santamaría A. S-allylcysteine protects against excitotoxic damage in rat cortical slices via reduction of oxidative damage, activation of Nrf2/ARE binding and BDNF preservation. Neurotoxicity Research. 2020; 38(4):929-940. (9 citas; factor de impacto 2.9)
19. Espinosa A, Meneses G, Chavarría A, Mancilla R, Pedraza-Chaverri J, Fleury A, Bárcena B, Pérez-Osorio IN, Besedovsky H, Arauz A, Fragoso G, Sciutto E. Intranasal Dexamethasone Reduces Mortality and Brain Damage in a Mouse Experimental Ischemic Stroke Model. Neurotherapeutics. 2020; 17(4):1907-1918. (17 citas; factor de impacto 5.6)
20. Ugalde-Muñiz P, Fetter-Pruneda I, Navarro L, García, E, Chavarría A. Chronic systemic inflammation exacerbates neurotoxicity in a Parkinson’s disease model. Oxidative Medicine and Cellular Longevity 2020; 2020:4807179. (26 citas; factor de impacto 7.3)
21. Martínez-Tapia RJ, Chavarría A, Navarro L. Differences in Diurnal Variation of Immune Responses in Microglia and Macrophages: Review and Perspectives. Cellular and Molecular Neurobiology 2020; 40(3): 301-309. (13 citas; factor de impacto 3.6)
22. Guzman-Ruiz MA, de la Mora MB, Torres X, Meza C, Garcia E, Chavarria A. Oral Silica Nanoparticles Lack of Neurotoxic Effects in a Parkinson’s Disease Model: a Possible Nanocarrier? IEEE Transactions on Nanobioscience 2019; 18(4):535-541. (7 citas; factor de impacto 3.7)
23. Pérez-Ramírez M, García-Méndez A, Siordia-Reyes AG, Chavarría A, Gómez C, García-Hernández N. Pediatric ependymoma: GNAO1, ASAH1, IMMT and IPO7 protein expression and 5-year prognosis correlation. Clinical Neurology and Neurosurgery 2019; 186: 105488. (3 citas; factor de impacto 1.9)
24. Ramírez-Serrano CE, Jiménez-Ferrer E, Herrera-Ruiz M, Zamilpa A, Vargas-Villa G, Ramírez-Carreto RJ, Chavarría A, Tortoriello J, Pedraza-Alva G, Pérez-Martínez L. A Malva parviflora´s fraction prevents the deleterious effects resulting from neuroinflammation. Biomedicine & Pharmacotherapy 2019; 118: 109349 (13 citas; factor de impacto 6.9).
25. Aguilera-Portillo G, Rangel-López E, Villeda-Hernández J, Chavarría A, Castellanos P, Elmazoglu Z, Karasu Ç, Túnez I, Pedraza G, Königsberg M, Santamaría A. The Pharmacological Inhibition of Fatty Acid Amide Hydrolase Prevents Excitotoxic Damage in the Rat Striatum: Possible Involvement of CB1 Receptors Regulation. Molecular Neurobiology. 2019; 56(2): 844-856. (26 citas; factor de impacto 4.6).
