Neurogenómica y Oncogenómica

Receptores hormonales en envejecimiento y neurodegeneración
Vías moleculares del factor ISG15 en tumores de cerebro
Modulación del proteoma por ISGilación
Regulación transcripcional y transducción de señales por interferón-gamma en cáncer

Publicaciones

1. Molecular interplay between the upregulated levels of Sad1 and UNC84 Domain Containing 2 (SUN2) and gene expression in medulloblastoma cells.
Tecalco-Cruz AC, Macías-Silva M, Sosa-Garrocho M, Poot-Hernández AC, Peralta-Alvarez CA, Ramírez-Jarquín JO, Cortes-González CC, Figueroa-Rivera L, López-Camarillo C.
Mol Biol Rep. 2024 Nov 19;51(1):1164. doi: 10.1007/s11033-024-10078-7.
PMID: 39560853
2. Adipocytes reprogram the proteome of breast cancer cells in organotypic three-dimensional cell cultures.
Tovar-Hernández K, Salinas-Vera YM, Carlos-Reyes Á, García-Hernández AP, Marchat LA, Mandujano-Lázaro G, Ríos-Castro E, Velasco-Suárez A, Mendez-Gómez I, Tecalco-Cruz ÁC, Ibarra-Sierra E, López-Camarillo C.
Sci Rep. 2024 Nov 7;14(1):27029. doi: 10.1038/s41598-024-76053-1.
PMID: 39505903 Free PMC article.
3. Editorial: Over 60 years of neurochemistry, the heritage of Dr. Ricardo Tapia.
Ramírez-Jarquín JO, Tecalco-Cruz AC, Lopez-Huerta VG, Ramírez-Jarquín UN.
Front Mol Neurosci. 2024 Mar 26;17:1398127. doi: 10.3389/fnmol.2024.1398127. eCollection 2024.
PMID: 38596778 Free PMC article. No abstract available.
4. Deregulation of interferon-gamma receptor 1 expression and its implications for lung adenocarcinoma progression.
Tecalco-Cruz AC, Medina-Abreu KH, Oropeza-Martínez E, Zepeda-Cervantes J, Vázquez-Macías A, Macías-Silva M.
World J Clin Oncol. 2024 Feb 24;15(2):195-207. doi: 10.5306/wjco.v15.i2.195.
PMID: 38455133 Free PMC article. Review.
5. Upregulation of the canonical signaling pathway of interferon-gamma is associated with glioblastoma progression.
Zamora-Salas SX, Macías-Silva M, Tecalco-Cruz AC.
Mol Biol Rep. 2024 Jan 3;51(1):64. doi: 10.1007/s11033-023-09062-4.
PMID: 38170343
6. TGF-β/SMAD canonical pathway induces the expression of transcriptional cofactor TAZ in liver cancer cells.
Ríos-López DG, Tecalco-Cruz AC, Martínez-Pastor D, Sosa-Garrocho M, Tapia-Urzúa G, Aranda-López Y, Ortega-Domínguez B, Recillas-Targa F, Vázquez-Victorio G, Macías-Silva M.
Heliyon. 2023 Oct 31;9(11):e21519. doi: 10.1016/j.heliyon.2023.e21519. eCollection 2023 Nov.
PMID: 38027697 Free PMC article.
7. Protein ISGylation: a posttranslational modification with implications for malignant neoplasms.
Tecalco-Cruz AC, Zepeda-Cervantes J.
Explor Target Antitumor Ther. 2023;4(4):699-715. doi: 10.37349/etat.2023.00162. Epub 2023 Aug 31.
PMID: 37711589 Free PMC article. Review.
8. Estrogen signaling via estrogen receptor alpha and its implications for neurodegeneration associated with Alzheimer's disease in aging women.
Tecalco-Cruz AC, López-Canovas L, Azuara-Liceaga E.
Metab Brain Dis. 2023 Mar;38(3):783-793. doi: 10.1007/s11011-023-01161-2. Epub 2023 Jan 14.
PMID: 36640216 Review.
9. Ubiquitin-Specific Peptidase 18: A Multifaceted Protein Participating in Breast Cancer.
Tecalco-Cruz AC, Ramírez-Jarquín JO, Zepeda-Cervantes J, Solleiro-Villavicencio H, Abraham-Juárez MJ.
In: Mayrovitz HN, editor. Breast Cancer [Internet]. Brisbane (AU): Exon Publications; 2022 Aug 6. Chapter 9.
PMID: 36122164 Free Books & Documents. Review.
10. Novel Breast Cancer Treatment by Targeting Estrogen Receptor-Alpha Stability Using Proteolysis-Targeting Chimeras (PROTACs) Technology.
Tecalco-Cruz AC, Ramírez-Jarquín JO, Macías-Silva M, Sosa-Garrocho M, López-Camarillo C.
In: Mayrovitz HN, editor. Breast Cancer [Internet]. Brisbane (AU): Exon Publications; 2022 Aug 6. Chapter 12.
PMID: 36122155 Free Books & Documents. Review.
11. Interferon-stimulated gene 15 and ISGylation are upregulated in glioblastoma.
Tecalco-Cruz AC, Velasco-Loyden G, Robles-Villarruel L, Cortes-González CC, Zepeda-Cervantes J, Pineda B, Chagoya de Sánchez V.
Biochem Biophys Res Commun. 2022 Sep 17;621:144-150. doi: 10.1016/j.bbrc.2022.07.011. Epub 2022 Jul 6.
PMID: 35834923
12. Decoding the Therapeutic Implications of the ERα Stability and Subcellular Distribution in Breast Cancer.
Tecalco-Cruz AC, Macías-Silva M, Ramírez-Jarquín JO, Ramírez-Jarquín UN.
Front Endocrinol (Lausanne). 2022 Apr 13;13:867448. doi: 10.3389/fendo.2022.867448. eCollection 2022.
PMID: 35498431 Free PMC article. Review.
13. Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection.
Tecalco Cruz AC.
Curr Drug Targets. 2022;23(7):686-691. doi: 10.2174/1389450123666220316094720.
PMID: 35297347
14. Protein degradation-associated mechanisms that are affected in Alzheimer´s disease.
Tecalco-Cruz AC, Pedraza-Chaverri J, Briones-Herrera A, Cruz-Ramos E, López-Canovas L, Zepeda-Cervantes J.
Mol Cell Biochem. 2022 Mar;477(3):915-925. doi: 10.1007/s11010-021-04334-8. Epub 2022 Jan 27.
PMID: 35083609 Review.
15. Implications of the Immune Polymorphisms of the Host and the Genetic Variability of SARS-CoV-2 in the Development of COVID-19.
Zepeda-Cervantes J, Martínez-Flores D, Ramírez-Jarquín JO, Tecalco-Cruz ÁC, Alavez-Pérez NS, Vaca L, Sarmiento-Silva RE.
Viruses. 2022 Jan 6;14(1):94. doi: 10.3390/v14010094.
PMID: 35062298 Free PMC article. Review.
16. Estrogenic hormones receptors in Alzheimer's disease.
Tecalco-Cruz AC, Zepeda-Cervantes J, Ortega-Domínguez B.
Mol Biol Rep. 2021 Nov;48(11):7517-7526. doi: 10.1007/s11033-021-06792-1. Epub 2021 Oct 16.
PMID: 34657250 Review.
17. TRIM25: A central factor in breast cancer.
Tecalco-Cruz AC, Abraham-Juárez MJ, Solleiro-Villavicencio H, Ramírez-Jarquín JO.
World J Clin Oncol. 2021 Aug 24;12(8):646-655. doi: 10.5306/wjco.v12.i8.646.
PMID: 34513598 Free PMC article. Review.
18. Identification of genes modulated by interferon gamma in breast cancer cells.
Tecalco-Cruz AC, Macías-Silva M, Ramírez-Jarquín JO, Méndez-Ambrosio B.
Biochem Biophys Rep. 2021 Jun 16;27:101053. doi: 10.1016/j.bbrep.2021.101053. eCollection 2021 Sep.
PMID: 34189281 Free PMC article.
19. Cellular Senescence and ApoE4: Their Repercussions in Alzheimer's Disease.
Tecalco-Cruz AC, Zepeda-Cervantes J, López-Canovas L, Ramírez-Jarquín JO, Pedraza-Chaverrí J, Briones-Herrera A.
CNS Neurol Disord Drug Targets. 2021;20(9):778-785. doi: 10.2174/1871527320666210628102721.
PMID: 34182916 Review.
20. Proteolysis-targeting chimeras and their implications in breast cancer.
Tecalco-Cruz AC, Zepeda-Cervantes J, Ramírez-Jarquín JO, Rojas-Ochoa A.
Explor Target Antitumor Ther. 2021;2(6):496-510. doi: 10.37349/etat.2021.00060. Epub 2021 Dec 31.
PMID: 36046115 Free PMC article. Review.
21. Molecular Pathways of Interferon-Stimulated Gene 15: Implications in Cancer.
Tecalco-Cruz AC.
Curr Protein Pept Sci. 2021;22(1):19-28. doi: 10.2174/1389203721999201208200747.
PMID: 33292152 Review.
22. Matrix metalloproteinases deregulation in amyotrophic lateral sclerosis.
Sánchez-Torres JL, Yescas-Gómez P, Torres-Romero J, Espinosa OR, Canovas LL, Tecalco-Cruz ÁC, Ponce-Regalado MD, Alvarez-Sánchez ME.
J Neurol Sci. 2020 Dec 15;419:117175. doi: 10.1016/j.jns.2020.117175. Epub 2020 Oct 11.
PMID: 33068904 Review.
23. Epigenetic basis of Alzheimer disease.
Tecalco-Cruz AC, Ramírez-Jarquín JO, Alvarez-Sánchez ME, Zepeda-Cervantes J.
World J Biol Chem. 2020 Sep 27;11(2):62-75. doi: 10.4331/wjbc.v11.i2.62.
PMID: 33024518 Free PMC article. Review.
24. Regulation and action of interferon-stimulated gene 15 in breast cancer cells.
Tecalco-Cruz AC, Ramírez-Jarquín JO, Cruz-Ramos E.
Hum Cell. 2020 Oct;33(4):954-962. doi: 10.1007/s13577-020-00414-x. Epub 2020 Aug 19.
PMID: 32813218 Review.
25. Non-muscle myosin IIA is post-translationally modified by interferon-stimulated gene 15 in breast cancer cells.
Cruz-Ramos E, Macías-Silva M, Sandoval-Hernández A, Tecalco-Cruz AC.
Int J Biochem Cell Biol. 2019 Feb;107:14-26. doi: 10.1016/j.biocel.2018.12.002. Epub 2018 Dec 5.
PMID: 30529400
26. Interplay between interferon-stimulated gene 15/ISGylation and interferon gamma signaling in breast cancer cells.
Tecalco-Cruz AC, Cortés-González CC, Cruz-Ramos E, Ramírez Jarquín JO, Romero-Mandujano AK, Sosa-Garrocho M.
Cell Signal. 2019 Feb;54:91-101. doi: 10.1016/j.cellsig.2018.11.021. Epub 2018 Nov 27.
PMID: 30500379
27. Estrogen Receptor Alpha and its Ubiquitination in Breast Cancer Cells.
Tecalco-Cruz AC, Ramírez-Jarquín JO, Cruz-Ramos E.
Curr Drug Targets. 2019;20(6):690-704. doi: 10.2174/1389450119666181015114041.
PMID: 30324876 Review.
28. Differential expression and molecular interactions of chromosome region maintenance 1 and calreticulin exportins in breast cancer cells.
Cruz-Ramos E, Sandoval-Hernández A, Tecalco-Cruz AC.
J Steroid Biochem Mol Biol. 2019 Jan;185:7-16. doi: 10.1016/j.jsbmb.2018.07.003. Epub 2018 Jul 5.
PMID: 29981820

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx