Contacto
Campos de conocimiento
Bioinformática
Biología Molecular y Celular de Microorganismos, Plantas y Animales
Ciencias Genómicas
Líneas de investigación
Biología del cáncer enfocado a la caracterización de alteraciones moleculares en tumores sólidos con impacto en el pronóstico y tratamiento. Carcinomas asociados a Virus de Papiloma Humano (VPH), en particular en cáncer cervicouterino y carcinomas escamosos de cabeza y cuello. Biomarcadores y diagnóstico molecular del cáncer.
Publicaciones
A45) Martínez-Bailón Cecilia; Mantilla-Morales Alejandra; Méndez-Matías Galo; Alvarado-Cabrero Isabel, MD; Maldonado Rogelio; Quintero-Becerra Joel; Arias-Flores Rafael; Patricia Piña-Sánchez. Human papillomavirus coinfections and p16ink4 expression in squamous penile carcinoma in Mexican patients. BMC Infect Dis. 2019;19(1):1068. doi: 10.1186/s12879-019-4696-6. FI 3.01.
A46) Manuel Nolasco‑Quiroga Marisol Rosas‑Díaz José Moreno Ricardo Godínez‑Aguilar María José López‑Ibarra Patricia Piña‑Sánchez Isabel Alvarado‑Cabrero Gerardo Vázquez‑Gómez Leticia Rocha‑Zavaleta Diego Arenas‑Aranda Fabio Salamanca‑Gómez. Increased expression of FAK isoforms as potential cancer biomarkers in ovarian cancer. Oncology letters 2019 Jun;17(6):4779-4786. DOI: 10.3892/ol.2019.10147 . FI 1.55
A47) Victor Granados García, Patricia Piña-Sánchez, Nancy Reynoso-Noveron, Yvonne N Flores, Filiberto Toledano Toledano, Gloria Estrada Gómez, Teresa Apresa García, Arely A Briseño. Medical cost to treat cervical cancer patients at a social security third level oncology hospital in Mexico City. Asian Pac J Cancer Prev. 2019 May 25;20(5):1547-1554. doi: 10.31557/APJCP.2019.20.5.1547. FI 1.77
A48) Ruiz-Esparza-Garrido R, Torres-López J, Piña-Sánchez P, Viedma-Rodríguez R, Rivera-González A, Velázquez-Flores MA. Expression changes of BIK in breast cancer tissues of different histological subtypes. Cir Cir. 2020;88(2):163-169. doi: 10.24875/CIRU.19001039. FI 0.35.
A49) Kirvis Torres-Poveda, Patricia Piña-Sánchez, Verónica Vallejo-Ruiz, Marcela Lizano, Aurelio Cruz-Valdez, Paula Juárez-Sánchez, Jaime de la Garza-Salazar; and Joaquín Manzo-Merino. Molecular markers for the diagnosis of high-risk HPV infection and triage of HPV-positive women. Rev Invest Clin. 2020;73(3):198-212. DOI: 10.24875/RIC.20000058. FI 1.45.
A50) Patricia Piña Sánchez, Hilda-Alicia Valdez-Salazar, Martha-Eugenia Ruiz-Tachiquín. Circulating microRNAs and their participation in the immune response in triple-negative breast cancer. Oncology letters. 2020;20(5):224. 2020. doi.org/10.3892/ol.2020.12087. FI 1.55.
A51) María Guadalupe Flores-Miramontes, Dominik Olszewski, Cristina Artaza-Irigaray, Anouk Willemsen, Ignacio G Bravo, Verónica Vallejo-Ruiz, Yelda Aurora Leal-Herrera, Patricia Piña-Sánchez, Andrea Molina-Pineda, Juan Carlos Cantón-Romero, María Guadalupe Martínez-Silva, Luis Felipe Jave-Suárez, Adriana Aguilar-Lemarroy. Detection of Alpha, Beta, Gamma, and Unclassified Human Papillomaviruses in Cervical Cancer Samples From Mexican Women. Front. Cell. Infect. Microbiol. 2020;10:234. DOI: 10.3389/fcimb.2020.00234. FI 4.12
A52) Lourdes Alvarez-Arellano, Pilar Eguía-Aguilar, Patricia Piña-Sánchez, Nadia González-García; Alam Palma-Guzman; Mario Perezpeña-Diazconti; Carmen Maldonado-Bernal. High expression of Toll-like receptor 7 is a survival factor in pediatric medulloblastoma. Child´s Nervous System, 2021. Doi:10.1007/s00381-021-05347-w
A53) Piña-Sanchez Patricia; Chavez-Gonzalez Antonieta; Ruiz-Tachiquin Martha; Vadillo Eduardo; Monroy-Garcia Alberto; Montesinos Juan Jose; Grajales Rocio; Gutierrez de la Barrera Marcos; Mayani Hector. Cancer biology, epidemiology and treatment in the 21st century: current status and future challenges from a biomedical perspective. Cancer Control. 2021 Jan-Dec; 28:10732748211038735. doi: 10.1177/10732748211038735.Cancer Control 2021. FI 3.42.
A54) Taniguchi-Ponciano K, Vadillo E, Mayani H, Gonzalez-Bonilla CR, Torres J, Majluf A, Flores-Padilla G, Wacher-Rodarte N, Galan JC, Ferat-Osorio E, Blanco-Favela F, Lopez-Macias C, Ferreira-Hermosillo A, Ramirez-Renteria C, Peña-Martínez E, Silva-Román G, Vela-Patiño S, Mata-Lozano C, Carvente-Garcia R, Basurto-Acevedo L, Saucedo R, Piña-Sanchez P, Chavez-Gonzalez A, Marrero-Rodríguez D, Mercado M. Increased expression of hypoxia-induced factor 1a mRNA and its related genes in myeloid blood cells from critically ill COVID-19 patients. Ann Med. 2021;53(1):197-207. doi: 10.1080/07853890.2020.1858234. FI 5.43.
A55) Galo Méndez-Matías, Cindy Velázquez-Velázquez, Rosario Castro-Oropeza, Alejandra Mantilla-Morales, Diana Ocampo-Sandoval, Ana Burgos-González, Carlos Heredia-Gutiérrez, Isabel Alvarado-Cabrero, Rosa Sánchez-Sandoval, Abigail Barco-Bazán, Fátima Chilaca-Rosas, Patricia Piña-Sánchez. Prevalence of HPV in Mexican Patients with Head and Neck Squamous Carcinoma and Identification of Potential Prognostic Biomarkers. Cancers 2021, 13(22), 5602.
A56) Espinosa, Magali Lizárraga, Floria Vázquez-Santillán, Karla Hidalgo-Miranda, Alfredo, Piña-Sánchez, Patricia, Torres Javier, García-Ramírez, Román A., Maldonado, Vilma, Melendez-Zajgla, Jorge, Ceballos-Cancino Gisela. Coexpression of Smac/DIABLO and estrogen receptor in breast cancer. Cancer Biomarkers 2021; 30(4=:429-446. DOI: 10.3233/CBM-200535. FI 4.38.
A57) María Teresa de Jesús Cervantes Díaz, Agni Jaim Muñoz Granados, Cindy Karina Velázquez Velázquez, Víctor Olguín Cruces, Nicolás Ramírez Torres, Verónica Gutiérrez Osorio, Fabio Abdel Salamanca Gómez, Patricia Piña Sánchez, Sergio Flores Hernández, Eunice López Muñoz. BIK and GRP78 protein expression as possible markers of response to preoperative chemotherapy and survival in breast cancer. TAOG 2021;60(2):245-252. DOI: 10.1016/j.tjog.2021.01.003. FI 1.5.
A58) Mayani H, Piña-Sánchez P, García-Foncillas J. Cancer in the 21st Century: a Multidisciplinary Perspective. Arch Med Res. 2022 Dec;53(8):721-722. doi: 10.1016/j.arcmed.2022.12.001. PMID: 36503606.
A59) Leal YA, Torres J, Gamboa R, Mantilla-Morales A, Piña-Sanchez P, Arrieta O, Bonifaz L, Meneses A, Duque C, Piñeros M. Cancer Incidence in Merida, Mexico 2015-2018: First Report from the Population-based Cancer Registry. Arch Med Res. 2022 Nov 30:S0188-4409(22)00157-6. doi: 10.1016/j.arcmed.2022.11.015. Epub ahead of print. PMID: 36462950.
A60) Piña-Sánchez P. Human Papillomavirus: Challenges and Opportunities for the Control of Cervical Cancer. Arch Med Res. 2022;53(8):753-769. doi: 10.1016/j.arcmed.2022.11.009.
A61) Castro-Oropeza Rosario, Piña-Sánchez Patricia. Epigenetic and Transcriptomic Regulation Landscape in HPV+ Cancers: Biological and Clinical Implications. Frontiers in Genetics, 2022; 13: 886613.
A62) Violeta Larios‑Serrato, José‑Darío Martínez‑Ezquerro, Hilda‑Alicia Valdez‑Salaz. Ar, Javier Torres, Margarita Camorlinga‑Ponce, Patricia Piña‑Sánchez and Martha‑Eugenia Ruiz‑Tachiquín. Copy number alterations and epithelial‑mesenchymal transition genes in diffuse and intestinal gastric cancers in Mexican patients. Molecular Medicine Reports, 2022.
A63) Sánchez-Ramírez D, Medrano-Guzmán R, Candanedo-González F, De Anda-González J, García-Rios LE, Pérez-Koldenkova V, Gutiérrez-de la Barrera M, Rodríguez-Enríquez S, Velasco-Velázquez M, Pacheco-Velázquez SC, Piña-Sánchez P, Mayani H, Gómez-Delgado A, Monroy-García A, Martínez-Lara AK, Montesinos JJ. High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma. Eur J Histochem. 2022 Feb 17;66(1):3360. doi: 10.4081/ejh.2022.3360. PMID: 35174683;
A64) Ana Lilia Remirez-Castellanos, Patricia Piña-Sanchez, Alejandra Mantilla-Morales, Wilfredo Valenzuela-Gonzalez, Fernando Candanedo González. Human Papillomavirus-Related Recurrent Multiphenotypic Sinonasal Carcinoma With HPV Genotype 56 Detected by HPV Direct Flow CHIP. Cureus. 2023 Jun 14;15(6):e40413. doi: 10.7759/cureus. 40413.
A65) Maria-Fatima Chilaca-Rosas, Manuel-Tadeo Contreras-Aguilar, Melissa Garcia-Lezama, David-Rafael Salazar-Calderon, Raul-Gabriel Vargas-Del-Angel, Sergio Moreno-Jimenez, Patricia Piña-Sanchez, Raul-Rogelio Trejo-Rosales, Felipe-Alfredo Delgado-Martinez, Ernesto Roldan-Valadez. Identification of Radiomic Signatures in Brain MRI Sequences T1 and T2 That Differentiate Tumor Regions of Midline Gliomas with H3. 3K27M Mutation. Diagnostics (Basel). 2023 Aug 14;13(16):2669. doi: 10.3390/diagnostics13162669.
A66) Vadillo E, Mantilla A, Aguilar-Flores C, De León-Rodríguez SG, Vela-Patiño S, Badillo J, Taniguchi-Ponciano K, Marrero-Rodríguez D, Ramírez L, León-Vega II, Fuentes-Castañeda C, Piña-Sánchez P, Prieto-Chávez JL, Pérez-Kondelkova V, Montesinos JJ, Bonifaz L, Pelayo R, Mayani H, Schnoor M.J The invasive margin of early-stage human colon tumors is infiltrated with neutrophils of an antitumoral phenotype. Leukoc Biol. 2023 Oct 11:qiad123. doi: 10.1093/jleuko/qiad123
A67) Jared E Limones Gonzalez, Perla Aguilar Esquivel, Karla Vazquez-Santillan, Rosario Castro-Oropeza, Floria Lizarraga, Vilma Maldonado, Jorge Melendez Zajgla, Patricia Piña-Sanchez, Gretel Mendoza Almanza. Changes in the molecular nodes of the Notch and NRF2 pathways in cervical cancer tissues from the precursor stages to invasive carcinoma. Oncology Letters. 2024, 28(5):1-14.
A68) Medrano Guzman R, Perez Ventura EF, Arias Rivera AS, Piña-Sanchez P, Brener Chaoul M. Clinicopathological Characteristics and the First Mutational Analysis of Gastrointestinal Stromal Tumors From Mexico: A Single Institution Experience. Cureus. 2024 Jun 18;16(6):e62594. doi: 10.7759/cureus.62594. PMID: 39027749; PMCID: PMC11256735.
A69) Larios-Serrato V, Valdez-Salazar HA, Torres J, Camorlinga M, Piña-Sánchez P, Minauro F, Ruiz-Tachiquín M. 2025. Analysis of biopsies of gastric cancer, intestinal and diffuse, and non-atrophic gastritis: an overview of loss of heterozygosity in Mexican patients. PeerJ 13:e18928
A70) Castro-Oropeza, R., Velazquez-Velazquez, C., Vazquez-Santillan, K., Mantilla-Morales, A., Ruiz Tachiquin, M. E., Torres, J., Rios-Sarabia, N., Mayani, H., & Piña-Sanchez, P. (2025). Landscape of lncRNAs expressed in Mexican patients with triple negative breast cancer. Molecular medicine reports, 31(6), 163.
