Contacto
Campos de conocimiento
Biología del Desarrollo
Biología Molecular y Celular de Microorganismos, Plantas y Animales
Ciencias Genómicas
Fisiología Molecular
Genética y Fisiología Celular
Neurobiología
Líneas de investigación
Regulación de la diferenciación del fenotipo TRHérgico en el hipotálamo por factores celulares.
Publicaciones
1.- Edgardo Madrid-Paulino, Dulce Mata-Espinosa, Juan León-Contreras, Isela Serrano-Fujarte, Sol Díaz de León-Guerrero, Tomás Villaseñor, José Puente, Rogelio Hernández-Pando, Leonor Pérez-Martínez, and Gustavo Pedraza-Alva (2022). Klf10 favors Mycobacterium tuberculosis survival by impairing Interferon gamma production and preventing macrophages reprograming to micropinocytosis. Journal of Leukocyte Biology. doi: 10.1002/JLB.4MA0422-288R.
2.- Elisa Medrano-Jiménez1, Karla F. Meza-Sosa1, José A. Urbán-Aragón1, Ismael Secundino2, Gustavo Pedraza-Alva1 and Leonor Pérez-Martínez1* (2022). Microglial activation in Alzheimer’s disease: The role of flavonoids and microRNAs. Journal of Leukocyte Biology 112, 47-77.
3.- Diaz de Leon-Guerrero, S., Salazar-Leon, J., Meza-Sosa, K.F., Valle-Garcia, D., Aguilar-Leon, D., Pedraza-Alva, G., Perez-Martinez, L*. (2022). An enriched environment reestablishes metabolic homeostasis by reducing obesity-induced inflammation. Disease Models and Mechanisms 1, 15(6):dmm048936
4.- Meza-Sosa, K.F., Miao, R., Navarro, F., Zhang, Z., Zhang, Y., Hu, J.J., Hartford, C.C., Li, X.L., Pedraza-Alva, G., Pérez-Martínez, L., Lal, A., Wu, H., Lieberman, J. (2022). SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage. Molecular Cell 17, 785-802.e10
5.- Morales-Tarre,O., Alonso-Bastida,R., Arcos-Encarnacion,B., Perez-Martinez,L., Encarnacion-Guevara,S. (2021). Protein lysine acetylation and its role in different human pathologies: a proteomic approach. Expert Review of Proteomics, 18 (11), 949-975.
6.- Arango-De la Pava, L. D., Zamilpa, A., Trejo-Espino, J. L., Dominguez-Mendoza, B. E., Jimenez-Ferrer, E., Perez-Martinez, L., Trejo-Tapia, G. (2021). Synergism and Subadditivity of Verbascoside-Lignans and -Iridoids Binary Mixtures Isolated from Castilleja tenuiflora Benth. on NF- k B/AP-1 Inhibition Activity. Molecules, 26, 547.
7.- Roberto C. Licea-Cejudo, Laura K. Arenas-Salgado, Jonathan Salazar-León, Mónica V. Martínez-Martínez, Alfonso Carreón-Rodríguez, Gustavo Pedraza-Alva, Leonor Pérez-Martínez*. (2020). A dysfunctional family environment and a high body fat percentage negatively affect telomere length in Mexican boys aged 8-10 years. Acta Pædiatrica doi:10.1111/apa.15234.
8.- Nilda C. Sánchez, Elisa Medrano-Jiménez, Diana Aguilar, Leonor Pérez-Martínez, Gustavo Pedraza-Alva1* (2020). TNF-induced miR-146a upregulation promotes human lung adenocarcinoma metastasis by targeting Merlin. DNA and Cell Biology, 39, 1-14.
9.- Salazar-León, J., Valdez-Hernández, A.L., García-Jiménez, S., Román- Domínguez, L., Huanosta-Murillo, E., Bonifaz, L.C., Pérez-Martínez, L. and Pedraza-Alva, G.* (2019). Nlrp1b1 negatively modulates obesity-induced inflammation by promoting IL-18 production. Scientific Reports, 9, 13815.
10.- Ramírez Serrano, C.E., Jiménez-Ferrer, E., Herrera-Ruiz, M., Zamilpa, A., Vargas-Villa, G., Tortoriello, J., Pedraza-Alva, G., and Pérez-Martínez, L.* (2019). A Malva parviflora´s fraction prevents the deleterious effects resulting from neuroinflammation. Biomedicine and Phamacotherapy, 118, 109349.
11.- Medrano-Jiménez, E., Jiménez-Ferrer Carrillo, I., Pedraza-Escalona, M., Álvarez-Arellano, L., Cortés-Mendoza, J., Herrera-Ruiz, M., Jiménez-Ferrer, E., Zamilpa, A., Tortoriello, J., Pedraza-Alva, G., and Pérez-Martínez, L. * (2019). Malva parviflora extract ameliorates the deleterious effects of high fat diet on the cognitive deficit in a mouse model of Alzheimer´s disease by restoring microglial function via a PPARgamma dependent mechanism. Journal of Neuroinflammation, 16, 143.
12.- Villaseñor, T., Madrid-Paulino, E., Maldonado-Bravo, R., Pérez-Martínez, L., and Pedraza-Alva, G.* (2019). Mycobacterium bovis BCG promotes IL-10 expression by establishing a SYK/PKCα/β positive autoregulatory loop that sustains STAT3 activation. Pathogens and Disease. 77, ftz032.
13.- Pedraza-Alva, G., Ramírez-Serrano, C.E., Pedraza, F., Flores-Vallejo, R.C., Villarrreal, M.L., Pérez-Martínez, L.* (2019) From traditional remedies to cutting-edge medicine: using ancient Mesoamerican knowledge to address complex disorders relevant to psychoneuroimmunology. Brain, Behavior, and Immunity 79, 3-5.
14.- Francisca Villanueva-Flores, Margarita Miranda-Hernández, José O. Flores-Flores, Alberto Porras-Sanjuanico, Hailin Hu, Leonor Pérez-Martínez, Octavio T. Ramírez, and Laura A. Palomares*. (2019). Poly(vinyl alcohol co-vinyl acetate) as a novel scaffold for mammalian cell culture and controlled drug release. Journal of Materials Science, 54, 7867-7882.
15.- Santos Ramírez-Carreto, Erick I. Pérez-García, Sandra I. Salazar-García, Johanna Bernaldez Sarabia, Alexei Licea-Navarro, Enrique Rudiño-Piñera, Leonor Pérez-Martínez, Gustavo Pedraza-Alva, Claudia Rodríguez-Almazán. (2019). Identification of a pore forming protein from the sea anemone Anthopleura dowii Verril (1869) venom by mass spectrometry. Journal of Venomous Animals and Toxins Including Tropical Diseases, 25, e1444118.
