-Diversidad fenotípica y genotípica de cepas multirresistentes de Salmonella Typhimurium ST213, un genotipo emergente en México potencial causante de infecciones sistémicas.

-Implicaciones funcionales del repertorio fimbrial de Escherichia coli enteropatógena y Citrobacter rodentium.

-¿Cómo se integran reguladores transcripcionales específicos adquiridos por transferencia horizontal y reguladores globales ancestrales para regular una isla de patogenicidad?

*Tenemos espacio para un estudiante

Publicaciones

75. Gutierrez-Huante, M., Martinez, H., Bustamante, V.H., Puente, J.L. and Sanchez, J. 2015. Bicarbonate enhances the in vitro antibiotic activity of kanamycin in Escherichia coli. Lett Appl Microbiol. 60:440-446
76. Caballero-Flores, G.G., Croxen, M., Martínez-Santos, V.I., Finlay, B.B. and Puente, J.L. 2015. Identification and regulation of a novel Citrobacter rodentium gut colonization fimbria (Gcf). J. Bacteriol. 197(8):1478-1491.
77. Kamada, N. Sakamoto, K. Seo, S.U. Zeng, M.Y. Kim, Y.G. Cascalho, M. Vallance, B.A. Puente, J.L. Nunez, G. 2015. Humoral Immunity in the Gut Selectively Targets Phenotypically Virulent Attaching-and-Effacing Bacteria for Intraluminal Elimination. Cell Host Microb. 17(5):617-627.
78. Silva, C., Calva, E., Calva, J.J., Wiesner, M., Fernandez-Mora, M. Puente, J.L. Vinuesa. 2015. Complete Genome Sequence of a Human-Invasive Salmonella enterica Serovar Typhimurium Strain of the Emerging Sequence Type 213 Harboring a Multidrug Resistance IncA/C Plasmid and a blaCMY-2-Carrying IncF Plasmid. Genome Announc. 3(6):e01323-15.
79. Vinuesa, P., Puente, J.L., Calva, E., Zaidi, M.B. and Silva, C., 2016. Complete Genome Sequence of Salmonella enterica Serovar Typhimurium Strain SO3 (Sequence Type 302) Isolated from a Baby with Meningitis in Mexico. Genome Announc. 4(2):e00285-16. doi: 10.1128/genomeA.00285-16.
80. Silva, C., Calva, E., Puente, J.L., Zaidi, M.B., and Vinuesa, P. 2016. Complete Genome Sequence of Salmonella enterica Serovar Typhimurium Strain YU15 (Sequence Type 19) Harboring the Salmonella Genomic Island 1 and Virulence Plasmid pSTV. Genome Announc. 4(2):e00252-16. doi: 10.1128/genomeA.00252-16.
81. Silva, C., Calva, E., Puente, J.L., Zaidi, M.B., and Vinuesa, P. 2016. Complete Genome Sequence of Salmonella enterica Serovar Typhimurium Strain SO2 (Sequence Type 302) Isolated from an Asymptomatic Child in Mexico. Genome Announc. 4(2):e00253-16. doi: 10.1128/genomeA.00253-16.
82. Colgan, A.M., Kröger, C., Diard, M., Hardt, W-D., Puente, J.L., Sivasankaran, S.K., Hokamp, K. and Hinton, J.C.D. (2016) The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium. PLoS Genet 12(8): e1006258. doi:10.1371/journal.pgen.1006258.
83. Soto, E., Espinosa, N., Díaz-Guerrero, M., Gaytán, M., Puente, J.L. and Gonzalez-Pedrajo, B. (2017). Functional Characterization of EscK (Orf4), a Sorting Platform Component of the Enteropathogenic Escherichia coli Injectisome. J. Bacteriol. 199(1). e00538-16.
84. Sakamoto, K., Kim, Y.G., Hara, H., Kamada, N., Caballero-Flores, G., Tolosano, E., Soares, M.P., Puente, J.L., Inohara, N. and Núñez, G. 2017. IL-22 Controls Heme/Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections. Science Immunol. 2, eaai8371.
85. Silva, C., Puente, J.L. and Calva, E. 2017. Salmonella virulence plasmid: pathogenesis and ecology. Pathog Dis. 75(6). doi: 10.1093/femspd/ftx070.
86. Puente, J.L. and Calva, E. 2017. Perspective: The One Health Concept - the Aztec empire and beyond. Pathog Dis. 75(6). doi: 10.1093/femspd/ftx062.
87. Montero, D.A., Velasco, J., del Canto, F., Puente, J.L., Padola, N., Rasko, D.A., Farfán, M., Salazar, J.C. and Vidal, R. 2017. Locus of Adhesion and Autoaggregation, a pathogenicity island present in emerging Shiga Toxin–producing Escherichia coli strains. Sci. Rep. 7:7011. doi:10.1038/s41598-017-06999-y
88. Iriarte, A., Giner-Lamia, J., Silva, C., Betancor, L., Astocondor, L., Cestero, J.J., Ochoa, T., García, C., Puente, J.L., Chabalgoity, J.A., The SalmoIber CYTED Network, and García-del Portillo, F. 2017. Draft Genome Sequence of Salmonella enterica subsp. enterica Serovar Infantis Strain SPE101, Isolated from a Chronic Human Infection. Genome Announc. 5(29). e00679-17
89. Quinones-Pena, M.A., Tavizon, G., Puente, J.L., Martinez-Anaya, C., Hernandez-Chinas, U. and Eslava, C.A. 2017. Effects of static magnetic fields on the enteropathogenic Escherichia coli. Bioelectromagnetics, 38, 570-578.
90. Silva, C., Zavala-Alvarado, C. and Puente, J.L. 2017. Self-conjugation of the enteropathogenic Escherichia coli adherence factor plasmid of four typical EPEC isolates. BioMed Research International. 2017: 6325736. doi:10.1155/2017/6325736.
91. Silva, C., Betancor, L., García, C., Astocondor, L., Hinostroza, N., Bisio, J., Rivera, J., Perezgasga, L., Pérez-Escanda, V., Yim, L., Jacobs, J., García-del Portillo, F, the SalmoIber CYTED Network, Chabalgoity, J.A. and Puente, J.L. 2017. Characterization of Salmonella enterica isolates causing bacteremia in Lima, Peru, using multiple typing methods. PLoS One. 12, e0189946.
92. Giner-Lamia, J., Vinuesa, P., Betancor, L., Silva, C., Bisio, J., Soleto, L., Chabalgoity, J.A., Puente, J.L., Garcia-Del Portillo F. 2019. Genome analysis of Salmonella enterica subsp. diarizonae isolates from invasive human infections reveals enrichment of virulence-related functions in lineage ST1256. BMC Genomics, 20, 99.
93. Montero, D.A., Del Canto, F., Velasco, J., Collelo, R., Padola, NL., Salazar, J.C., San Martin, C., Oñate, A., Blanco, J., Rasko, D.A., Contreras, C., Puente, J.L., Scheutz, F., Franz, E. and Vidal, R. 2019. Cumulative acquisition of pathogenicity islands has shaped virulence potential and contributed to the emergence of LEE-negative Shiga toxin-producing Escherichia coli strains. Emerging Microbes & Infections. 8, 486-502.
94. Cornejo-Granados, F., Calderon de la Barca, A.M., Torres, N., Martinez-Romero, E., Torres, T., Lopez-Vidal, Y., Soberon, X., Partida-Martinez, L., Pinto-Cardoso, S., Alcaraz, L.D., Pardo-Lopez, L., Canizales-Quinteros, S., Puente, J.L. and Ochoa-Leyva, A. 2019. Microbiome-MX 2019: Microbiota and Microbiome opportunities in Mexico, a megadiverse country. Research in Microbiology. 170:235-241. doi.org/10.1016/j.resmic.2019.03.001.
95. Silva, C., Calva, E., Fernández-Mora, M., Puente, J.L., and Vinuesa, P. 2019. Population analysis of D6-like plasmid prophage variants associated with specific IncC plasmid types in the emerging Salmonella Typhimurium ST213 genotype. PLoS One. 14, e0223975.
96. Lara-Ochoa, C., Gonzalez-Lara, F., Romero-Gonzalez, L.E., Jaramillo-Rodriguez, J.B., Vazquez-Arellano, S.I., Medrano-Lopez, A., Cedillo-Ramirez, L., Martinez-Laguna, Y., Giron, J.A., Perez-Rueda, E., Puente, J.L., Ibarra, J.A. 2021. The transcriptional activator of the bfp operon in EPEC (PerA) interacts with the RNA polymerase alpha subunit. Scientific Reports, 11 (1), 8541. doi.org/10.1038/s41598-021-87586-0.
97. Perez-Sepulveda BM, Heavens D, Pulford CV, Predeus AV, Low R, Webster H, Dykes GF, Schudoma C, Rowe W, Lipscombe J, Watkins C, Kumwenda B, Shearer N, Costigan K, Baker KS, Feasey NA, Hinton JCD, Hall N; 10KSG consortium. 2021. An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes. Genome Biol. 21;22(1):349. doi: 10.1186/s13059-021-02536-3. *Publicación como parte del 10KSG consortium.
98. Saldana-Ahuactzi, Z., Soria-Bustos, J., Martinez-Santos, V.I., Yanez-Santos, J.A., Martinez-Laguna, Y., Cedillo-Ramirez, M.L., Puente, J.L., Giron, J.A. 2022. The Fis Nucleoid Protein Negatively Regulates the Phase Variation fimS Switch of the Type 1 Pilus Operon in Enteropathogenic Escherichia coli. Frontiers in Microbiology. 13:882563. doi: 10.3389/fmicb.2022.882563.
99. Madrid-Paulino, E., Mata-Espinosa, D., León-Contreras, J., Serrano-Fujarte, I., Díaz de León-Guerrero, S., Villaseñor, T., Ramón-Luing, L., Puente, J.L. Chávez-Galán, L., Hernández-Pando, R., Pérez-Martínez, L. and Pedraza-Alva, G. 2022. Klf10 favors Mycobacterium tuberculosis survival by impairing Interferon gamma production and preventing macrophages reprograming to micropinocytosis. Journal of Leukocyte Biology. 112(3):475-490. doi: 10.1002/JLB.4MA0422-288R.
100. Suwandi, A., Alvarez, K.G., Galeev, A., Steck, N., Riedel, C.U., Puente, J.L., Baines, J.F., Grassl, G.A. 2022. B4galnt2-mediated host glycosylation influences the susceptibility to Citrobacter rodentium infection. Frontiers in Microbiology. 11;13:980495. doi: 10.3389/fmicb.2022.980495.
101. Lara, C., Huerta, A., Medrano, A., Deng, W., Finlay, B.B., Martínez, Y. and Puente, J.L. 2023. GrlR, a negative regulator in enteropathogenic E. coli, also represses the expression of LEE virulence genes independently of its interaction with its cognate partner GrlA. Frontiers in Microbiology. 14:1063368. doi.org/10.3389/fmicb.2023.1063368
102. Serrano-Fujarte, I., Calva, E., García-Domínguez, J., Ortiz-Jiménez, S. and Puente, J.L. 2024. Population structure and ongoing microevolution of the emerging multidrug-resistant Salmonella Typhimurium ST213. npj Antimicrobials and Resistance. En prensa.

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx