Metabolismo del pirofosfato (PPi), pirofosfatasas (PPasa) y estrés abiótico en plantas superiores.
El PPi se produce en biosíntesis y la PPasa lo reciclan e impulsan el crecimiento. En plantas, la evidencia indica una relación entre el PPi, la germinación, desarrollo, adaptación al estrés abiótico, y metabolismo de carbohidratos y lípidos. Entender tal relación es el interés de nuestro grupo, en modelos como Arabidopsis, fríjol y chile. Se emplean enfoques experimentales e in silico.

Publicaciones

1---Gutiérrez-Luna FM , de la Sancha EN , Valencia-Turcotte LG , Vázquez-Santana S , & Rodríguez-Sotres R (2016) Evidence for a non-overlapping subcellular localization of the family I isoforms of soluble inorganic pyrophosphatase in Arabidopsis thaliana. Plant Science 253(supplement C):229 - 242.
2---Páez-Franco JC , González-Sánchez I , Gutiérrez-Nájera NA , Valencia-Turcotte LG , Lira-Rocha A , Cerbón MA , & Rodríguez-Sotres R (2017) Proteomic Profiling Reveals the Induction of UPR in Addition to DNA Damage Response in HeLa Cells Treated With the Thiazolo[5,4-b]Quinoline Derivative D3ClP. J Cell Biochem 118(5):1164-1173.
3---García-Valencia LE , Bravo-Alberto CE , Wu H , Rodríguez-Sotres R , Cheung AY , & Cruz-García F (2017) SIPP, a Novel Mitochondrial Phosphate Carrier, Mediates in Self-Incompatibility. Plant Physiol 175(3):1105--1120.
4---Maya-Bernal JL , Ávila A , Ruiz-Gayosso A , Trejo-Fregoso R , Pulido N , Sosa-Peinado A , Zúñiga-Sánchez E , Martínez-Barajas E , Rodríguez-Sotres R , & Coello P (2017) Expression of recombinant SnRK1 in E. coli. Characterization of adenine nucleotide binding to the SnRK1.1/AKINβγ-β3 complex. Plant Sci 263(Suppl C):116-125.
5---Gutiérrez-Luna FM , Hernández-Domínguez EE , Valencia-Turcotte LG , & Rodríguez-Sotres R (2018) Review: "Pyrophosphate and pyrophosphatases in plants, their involvement in stress responses and their possible relationship to secondary metabolism''. Plant Science 267(Supplement C):11 - 19.
6---Banda-Vázquez J , Shanmugaratnam S , Rodríguez-Sotres R , Torres-Larios A , Höcker B , & Sosa-Peinado A (2018) Redesign of LAOBP to bind novel l-amino acid ligands. Protein Science 27(5):957-968.
7---Carrillo-Campos J , Riveros-Rosas H , Rodríguez-Sotres R , & Muñoz-Clares RA (2018) Bona fide choline monoxygenases evolved in Amaranthaceae plants from oxygenases of unknown function: Evidence from phylogenetics, homology modeling and docking studies. PLOS ONE 13(9):1-23.
8---Brito-Sánchez, S. C.; Zaragoza-Pérez ,F.A.; Olivera-Flores T.dJ.; Rivero-Cruz J.F. , Amacosta J.; Gutiérrez-Luna, F.M.; Valencia-Turcotte L.G.; & Rodríguez-Sotres R* (2019) Biolistics transformation of callus and cell suspension cultures of Capsicum annuum L. `serrano ́ useful for in vitro studies of secondary metabolite relative contents. Acta Agrobotanica 72(4):1792, PP. 1-18, DOI: 10.5586/aa.1792
9---Torres-Rodríguez María Daniela, González-Segura Lilian, Rodríguez-Sotres Rogelio, Juárez-Díaz Javier Andrés, Cruz-ZamoraYuridia, Cruz-Garciá Felipe. (2020). High resolution crystal structure of NaTrxh from Nicotiana alata and its interaction with the S-RNase. Journal of Structural Biology. 212 (1), 107578, https://doi.org/10.1016/j.jsb.2020.107578
10----Pérez-Vásquez, A., Díaz-Rojas, M., Castillejos-Ramírez, E. V., Pérez-Esquivel, A., Montaño-Cruz, Y., Rivero-Cruz, I., Torres-Colín, R., González-Andrade, M., Rodríguez-Sotres, R., Gutiérrez-González, J. A., Madariaga-Mazón, A., and Mata, R. Protein tyrosine phosphatase 1B inhibitory activity of compounds from Justicia spicigera (Acanthaceae). Phytochemistry 203113410 (2022) DOI: "10.1016/j.phytochem.2022.113410".
11---Trejo-Fregoso, R., Rodríguez, I., Ávila, A., Juárez-Díaz, J. A., Rodríguez-Sotres, R., Martínez-Barajas, E., and Coello, P. Phosphorylation of S11 in PHR1 negatively controls its transcriptional activity. Physiologia Plantarum 174(6):e13831 (2022) DOI: "10.1111/ppl.13831".
12---Castro-Rodríguez, J.A.; Rodríguez-Sotres, R.; Farrés, A. (2023) Determinants for an Efficient Enzymatic Catalysis in Poly(Ethylene Terephthalate) Degradation. Catalysts, 13, 591. https://doi.org/10.3390/catal13030591

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx