-PRODUCCIÓN FERMENTATIVA DE METABOLITOS SECUNDARIOS DE INTERES BIOMÉDICO: ESTUDIOS BIOQUÍMICOS Y MOLECULARES DE SU SÍNTESIS
-AISLAMIENTO Y CARACTERIZACIÓN DE MICROORGANISMOS ENDÓFITOS DE PLANTAS MEDICINALES. EVALUACIÓN DE LOS MISMOS POR SU CAPACIDAD PARA SINTETIZAR METABOLITOS SECUNDARIOS CON POTENCIAL FARMACOLÓGICO.
-MINERÍA GENÓMICA: BUSQUEDA DE METABOLITOS SECUNDARIOS DE IMPORTANCIA BIOMÉDICA.

Publicaciones

-Guzmán-Trampe S, Ikeda H, Vinuesa P, Macías-Rubalcava ML, Esquivel B, Centeno-Leija S, Tapia-Cabrera SM, Mora-Herrera SI, Ruiz-Villafán B, Rodríguez-Sanoja R, and Sanchez S. Production of distinct labdane-type diterpenoids using a novel cryptic labdane-like cluster from Streptomyces thermocarboxydus K155. Appl. Microbiol. Biotechnol. 104(2):741-750. 2020. IF: 3.53 https://doi.org/10.1007/s00253-019-10240-3
-Martin JF, Liras P, and Sánchez S. Modulation of gene expression in Actinobacteria by translational modification of transcriptional factors and secondary metabolite biosynthetic enzymes. Front. Microbiol. 12:630694. 2021. IF: 4.25 doi: 10.3389/fmicb.2021.630694.
-Rocha-Mendoza D, Manzo-Ruiz M, Romero-Rodríguez A, Ruiz-Villafán B, Rodríguez-Sanoja R, Sánchez S. Dissecting the role of the two Streptomyces peucetius var. caesius glucokinases in the sensitivity to carbon catabolite repression. J Ind Microbiol Biotechnol. 48(9-10): (8 pag)kuab047. 2021. IF: 3.34 Doi: https://doi.org/10.1093/jimb/kuab047
-Caicedo-Montoya C, Gómez-Román MP, Vázquez-Hernández M, Mora-Rincón RA, Rodriguez-Luna SD, Rodríguez-Sanoja R, Sanchez S. Evolutionary genomics and biosynthetic potential of novel environmental Actinobacteria. Appl Microbiol Biotechnol. 105: 8805-8822. 2021. IF: 4.813 https://doi.org/10.1007/s00253-021-11659-3
-Passari A, Sánchez S. Actinobacteria: recent trends in genomics, omics study and discovery of novel natural products. (Editorial). Front Microbiol 12: 799737. 2021. IF: 4.07 https://doi.org/10.3389/fmicb.2021.799737
- Ruiz-Villafán B, Cruz-Bautista R, Manzo-Ruiz M, Kumar Passari A, Villarreal-Gómez K, Rodríguez-Sanoja R, and Sánchez S. Carbon catabolite regulation of secondary metabolite formation, an old but not well-established regulatory system. Microb. Biotechnol. 15(4): 1058-1072. 2022. IF: 4.69 doi: https://doi.org/10.1111/1751-7915.13791
-Ramirez-Rendón D, Kumar Passari A, Ruiz-Villafán B, Rodríguez-Sanoja R, Sánchez S, Demain AL. Impact of novel microbial secondary metabolites on the pharma – industry. Appl Microbiol Biotechnol. 106: 1855–1878. 2022. IF: 5.56 https://link.springer.com/article/10.1007/s00253-022-11821-5
- Rodríguez-Peña K, Gómez-Román M.P., Macías-Rubalcava M.L., Rocha-Zavaleta L, Rodríguez-Sanoja R and Sánchez S. Bioinformatic comparison of three Embleya species and description of steffimycins production by Embleya sp. NF3. Appl Microbiol Biotechnol. 106:3173-3190. 2022. IF: 5.56 https://doi.org/10.1007/s00253-022-11915-0
-Romero-Rodríguez A. Martínez de la Peña C, Troncoso-Cotal S, Guzmán C, Sánchez S. Emerging alternatives against Clostridioides difficile infection. Anaerobe. 78: 102638. IF: 3.33
doi: 10.1016/j.anaerobe.2022.102638.
-Cruz-Bautista R, Ruíz-Villafán B, Romero-Rodríguez A, Rodríguez-Sanoja R, Sanchez S. Trends in the two-component system’s role in the synthesis of antibiotics by Streptomyces. Appl Microbiol Biotechnol. 2023. 107: 4727-4743. IF: 5.0 https://doi.org/10.1007/s00253-023-12623-z
-Kumar Passari A, Ruiz-Villafán B, Cruz-Bautista R, Díaz-Domínguez V, Rodríguez-Sanoja R, Sánchez S. Opportunities and challenges of microbial siderophores in the medical field. Appl Microbiol Biotechnol. 2023. 107(22):6751-6759. IF: 5.0 doi.: 10.1007/s00253-023-12742-7.
-Ramirez-Rendon D, Guzmán-Chávez F, García-Ausencio C, Rodríguez-Sanoja R, Sánchez S*. The untapped potential of actinobacterial lanthipeptides as therapeutic agents. Mol Biol Rep. 2023, 50(12):10605-10616. IF: 2.74 doi: 10.1007/s11033-023-08880-w
-Cruz-Bautista R, Zelarayan-Agüero A, Ruiz-Villafán B, Escalante-Lozada A, Rodríguez-Sanoja R, Sánchez S. An overview of the two-component system GarR/GarS role on antibiotic production in Streptomyces coelicolor. Appl Microbiol Biotechnol. 2024. 108: 306 IF: 5.0 Doi: 10.1007/s00253-024-13136-z
-Romero-Rodríguez A, Espino-Mares B, Ruíz-Villafán B, Sánchez S. Is there a role for intestinal sporobiota in the antimicrobial resistance crisis?  Microbiol Res 2024. 288:127870. IF: 6.1 https://doi.org/10.1016/j.micres.2024.127870
-Reyna-Campos AO, Ruiz-Villafan B, Macías-Rubalcava ML, Langley E, Rodríguez-Sanoja R, Sánchez S. Heterologous expression of lasso peptides with apparent participation in the morphological development in Streptomyces. Appl. Microbiol. Biotechnol. Express. 2024. 14:97 IF: 3.8 doi: https://doi.org/10.1186/s13568-024-01761-w
Roblero-Mejía DO, García-Ausencio C, Rodríguez-Sanoja R, Guzmán-Chávez F, Sánchez S. Embleporicin: A novel class I lanthipeptide from the actinobacteria Embleya sp. NF3. Antibiotics. 2024. 13:1179. IF: 4.3 https://doi.org/10.3390/antibiotics13121179

Circuito de Posgrado, Ciudad Universitaria
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