Genética molecular de la respuesta de detección de quórum de Pseudomonas aeruginosa.
Producción heteróloga del biosurfactante ramnolípidos en Pseudomonas chlororaphis.
Evolución de bacterias.

Publicaciones

1. Soto-Aceves, MP, Cocotl-Yañez, M., Merino, E, Castillo-Juárez, I. Cortés-López, H., González-Pedrajo, B., Díaz-Guerrero, M., Servín-González, L., Soberón-Chávez, G (corresponding author). Inactivation of the quorum-sensing transcriptional regulators LasR or RhlR does not suppress the expression of virulence factors and the virulence of Pseudomonas aeruginosa PAO1. Microbiology. 165(4): 425-432. 2019. FI: 2.7. DOI 10.1099/mic.0.000778.
2. Gutiérrez-Gómez U, Servín-González L, Soberón-Chávez, G (corresponding author) Role of -oxidation and de novo fatty acid synthesis in the production of rhamnolipids and polyhydroxyalkanoates by Pseudomonas aeruginosa. Appl Microbiol Biotechnol. 103(9): 3753-3760. 2019. FI: 4.69. DOI: 10.1007/s00253-019-09734-x.
3. García-Ulloa M, Ponce-Soto GY, González-Valdez A, González-Pedrajo B, Díaz-Guerrero M, Souza V, Soberón-Chávez G (corresponding author) Two Pseudomonas aeruginosa clonal groups belonging to the PA14 clade are indigenous to the Churince system in Cuatro Ciénegas Coahuila, México. Environ Microbiol. 21(8): 2964-2976. 2019. FI: 5.4. DOI: 10.1111/1462-2920.14692.
4. Arroyo-Pérez EE, González-Cerón G, Soberón-Chávez G, Georgellis D, Servín-González L. A novel two-component system, encoded by sco5282/sco5283 genes, affects Streptomyces coelicolor morphology in liquid culture. Frontiers Microbiol. 10: 1568. 2019. FI: 4.076. DOI: 10.3389/fmicb.2019.01568.
5. Martínez-Carranza E, Ponce-Soto GY, Servín-González L, Alcaraz LD, Soberón-Chávez G (corresponding author) Evolution of bacteria seen through their essential genes: The case of Pseudomonas aeruginosa and Azotobacter vinelandii. Microbiology-SGM. 165(9): 976-984. 2019. FI: 2.138. DOI: 10.1099/mic.0.000833.
6. García-Reyes S, Soberón-Chávez G. Cocotl-Yañez M. The third quorum sensing system of Pseudomonas aeruginosa: Pseudomonas quinolone signal and the enigmatic PqsE protein. J. Med Microbiol 69: 25-34. 2020. FI: 2.156. DOI: 10.1099.jmmm.0.001116.
7. Martínez-Carranza E, García-Reyes S, González-Valdez A, Soberón-Chávez G (corresponding author) Tracking the genome of four Pseudomonas aeruginosa isolates that have a defective Las quorum-sensing system but are still virulent. Access Microbiol. 2(7): 1-7. 2020. DOI: 10.1099/acmi.0.000132.
8. García-Contreras R, Loarca D, Pérez-González C, Jiménez-Cortés G, González-Valdez A, Soberón-Chávez G. Rhamnolipids stabilize quorum sensing mediated cooperation in Pseudomonas aeruginosa. FEMS Microbiol Lett. 367(10): fnaa080. 2020. FI: 2.74 doi: 10.1093/femsle/fnaa080.
9. Cocotl-Yañez M, Soto Aceves M, Gonzalez-Valdez A, Servín-González L, Soberon-Chavez G. Virulence factors regulation by the quorum-sensing and Rsm systems in the marine strain Pseudomonas aeruginosa ID4365, a natural mutant in lasR. FEMS Microbiol Lett. 367(12): fnaa092. 2020. FI 2.74 DOI: 10.1093/femsle/fnaa092
10. García-Reyes S, Soto-Aceves MP, Cocotl-Yañez M, González-Valdez, Servín-González L, Soberón-Chávez G (corresponding author) The outlier Pseudomonas aeruginosa strain ATCC 9027 harbors a defective LasR quorum-sensing transcriptional regulator. FEMS Microbiol Lett. 367(16): fnaa122. 2020. FI: 2.74. DOI: 10.1093/femsle/fnaa122
11. Soberón-Chávez G (corresponding author), González-Valdez A, Soto-Aceves MP, Cocotl-Yañez M. Rhamnolipids produced by Pseudomonas: from molecular genetics to the market. Microbial Biotechnol (MBT) 14(1): 136–146. 2021. FI: 5.328. DOI:10.1111/1751-7915.13700.
12. Soto-Aceves MP, Cocotl-Yañez M, Servín-González S, Soberón-Chávez G (corresponding author). The Rhl quorum sensing system is at the top of the regulatory hierarchy under phosphate limiting conditions in Pseudomonas aeruginosa PAO1. J. Bacteriol. 203(5): eoo475-20. 2021. FI: 3.004. DOI: 10.1128/JB.00475-20.
13. García-Reyes S, Moustafa DA, Attrée I, Goldberg JB, Quiroz-Morales SE, Soberón-Chávez G (corresponding author) Vfr or CyaB promote the expression of the pore-forming toxin exlBA operon in Pseudomonas aeruginosa ATCC 9027 without increasing its virulence in mice. Microbiology (Reading). 167(8): 001083. 2021. FI: 2.7. DOI: 10.1099/mic.0.001083
14. García-Reyes S, Cocotl-Yañez M, Soto-Aceves, MP, González-Valdez A, Servín-González L, Soberón-Chávez G (corresponding author) PqsR-independent quorum-sensing response of Pseudomonas aeruginosa ATCC 9027 outlier-strain reveals new insights on the PqsE effect on RhlR activity. Mol Microbiol. 116(4): 1113-1123. 2021.FI: 3.816 DOI:10.1111/mmi.14797.
15. Soberón-Chávez G (corresponding author), Hausmann R, Déziel E. Editorial. Biosurfactants: Insights in their biosynthesis, Production and Applications. Front Bioeng Biotechnol. 9: 933. 2021. FI: 5.89. https://doi.org/10.3389/fbioe.2021.769899.
16. Quiroz-Morales SE, García-Reyes S, Ponce-Soto GY, Servín-González L, Soberón-Chávez G (corresponding author) Tracking the origins of Pseudomonas aeruginosa phylogroups by diversity and evolutionary analysis of important pathogenic marker genes. Diversity 14(5): 345. 2022 https://doi.org/10.3390/d14050345. Publicado dentro del número especial “Recent trends in bacterial diversity and evolution, editado por G. Soberón-Chávez. FI: 3.09.
17. Soto-Aceves M, González-Valdez A, Cocotl-Yañez M, Soberón-Chávez G. Pseudomonas aeruginosa LasR overexpression leads to a RsaL-independent pyocyanin production inhibition in a low phosphate condition Microbiology (Reading). 168(10) 2022. FI 2.7. DOI 10.1099/mic.0.001262.
18. Montelongo-Martínez LF, Hernández-Méndez C, Muriel-Millán LF, Hernández-Estrada R, Fabian-Del Olmo Misael J, González-Valdez A, Soberón-Chávez G, Cocotl-Yañez M. Unraveling the regulation of pyocyanin synthesis by RsmA through MvaU and RpoS in Pseudomonas aeruginosa ID4365. J Basic Microbiol. 63: 53-63. 2023. FI 2.65. https://doi.org/10.1002/jobm.202200432.
19. Rodríguez-Martínez K, Muriel-Millán LF, Ortíz-Vasco C, Moreno S, Soberón-Chávez G, Espín G. Defining the regulatory mechanisms of sigma factor RpoS degradation in Azotobacter vinelandii and Pseudomonas aeruginosa. Mol Microbiol. 120(1):91-102. 2023. FI 3.98. DOI: 10.1111/mmi.15107.
20. Quiroz-Morales SE, Muriel-Millán LF, Ponce-Soto GY, González-Valdez A, Castillo-Juárez I, Servín-González L, Soberón-Chávez G (corresponding author). Pseudomonas aeruginosa strains belonging to phylogroup 3 frequently exhibit an atypical quorum sensing response: The case of MAZ105, a tomato-rhizosphere isolate. Microbiology (Reading) 169(10): 001401 2023. FI 2.95 DOI 10.1099/mic.0.001401.
21. Soberón Chávez, G. (corresponding author). Some insights on traditional and novel approaches in microbial biotechnology that contribute to the United Nations Sustainable Development Goals. Microbial Biotechnol (MBT). 2023 16(11):2015-2018. FI: 6.575 DOI: 10.1111/1751-7915.14318.
22. González-Valdez A, Escalante A, Soberón-Chávez G (corresponding author) Heterologous production of rhamnolipids in Pseudomonas chlororaphis subsp chlororaphis ATCC 9446 based on the endogenous production of N-acyl-homoserine lactones. Microbial Biotechnol (MBT). 17(1): e14377. 2024. FI: 6.575. DOI:10.1111/1751-7915.14377.
23. Muriel-Millán LF, Montelongo-Martínez LF, González-Valdez A. Bedoya-Pérez, LP, Cocotl-Yañez M, Soberón Chávez G (corresponding author). The alternative sigma factor RpoS regulates Pseudomonas aeruginosa quorum sensing by repressing the pqsABCDE operon and activating vfr. Mol Microbiol. 121(2): 291-303 2024. FI 3.98 DOI:10.1111/mmi.15224.
24. González-Valdez A, Hernández-Pineda J, Soberón-Chávez G (corresponding author). Detection and quantification of mono-rhamnolipids and di-rhamnolipids produced by Pseudomonas aeruginosa. J Vis Exp. (JoVE), (205) e65934 2024 Enlace: https://www.jove.com/video/65934 FI 1.35. DOI:10.3791/65934.
25. Romero-González LE, Montelongo-Martínez LF, González-Valdez A, Quiroz-Morales SE, Cocotl-Yañez M, Franco-Cendejas R, Soberón-Chávez G, Pardo-López L, Bustamante VH. Pseudomonas aeruginosa isolates from water samples of the Gulf of Mexico show similar virulence properties but different antibiotic susceptibility profiles than clinical isolates. Int J. Microbiol. Volume 2024, Article ID 6959403, 2024. DOI 10.1155/2024/6959403 FI: 3.4.
26. Hausmann R, Déziel E Soberón-Chávez G Editorial: Microbial biosurfactants:updates on their biosynthesis, production and applications. Front. Bioeng. Biotechnol. 12:1433035. 2024 DOI 10.3389/fbioe.2024.1433035 FI: 5.7.
27. Montelongo-Martínez LF, Díaz-Guerrero M, Flores-Vega VR, Soto-Aceves MP, Rosales-Reyes R, Quiroz-Morales SE, González-Pedrajo B, Soberón-Chávez G, Cocotl-Yañez M. The quorum sensing regulator RhlR positively controls the expression of the type III secretion system in Pseudomonas aeruginosa PAO1. PLoS ONE. 19(8):e0307174. 2024. doi: 10.1371/journal.pone.0307174. FI: 3.75
28. González-Valdez A, Vázquez-Bueno PG, Hernández-Pineda J, Soberón-Chávez G (corresponding author). Synthesis of di-rhamnolipids by the avirulent, mono-rhamnolipid producing strain Pseudomonas aeruginosa ATCC 9027. Biotechnol Lett Aceptado para su publicación el 3 de agosto del 2024 DOI 10.1007/s10529-024-03527-7. FI: 2.71

Libros editados:
1. Gloria Soberón-Chávez, Eric Déziel, Rudolph Hausmann (editors). Biosurfactants: New insights in their biosynthesis, production and applications. Frontiers in Bioengineering and Biotechnology. Libro electrónico publicado en línea el 24 de enero del 2022.
(https://www.frontiersin.org/research-topics/12023/biosurfactants-new-insights-in-their-biosynthesis-production-and-applications).
2. Gloria Soberón Chávez (editor). Biosurfactants: Research and Development. Foundations and Frontiers in Enzymology, Elsevier, Academic Press. 334 páginas; 11 de enero del 2023.
3. Gloria Soberón Chávez (editor). Biosurfactants: Research and Development. Foundations and Frontiers in Enzymology, Elsevier, Academic Press. London, UK, 334 páginas; 11 de enero del 2023. Publicado en línea 21 de octubre del 2022. ISBN 9780323916974.

PATENTE CONCEDIDA
1. Gloria Soberón Chávez, Uriel Gutiérrez Gómez. “Método para la construcción de cepas del género Pseudomonas para disminuir su virulencia e incrementar su producción de ramnolípidos, y productos obtenidos con el mismo”. Patente otorgada por el Instituto Mexicano de la Propiedad Industrial (IMPI) MX/a/2019/006840, el 21 de mayo del 2024.

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx