Contacto
Campos de conocimiento
Biología del Desarrollo
Neurobiología
Líneas de investigación
Células troncales del Sistema Nervioso.
Trasplante de neuronas en modelos de enfermedades neurodegenerativas.
Reprogramación de células somáticas humanas a estado pluripotencial.
Regeneración del cerebro de ajolote.
Publicaciones
55. S. Cerrizuela, G. Vega-López, K. Méndez-Maldonado, I. Velasco, M. J. Aybar*. 2022. The crucial role of model systems in understanding the complexity of cell signaling in human neurocristopathies. WIREs Mech Dis, 14: e1537 (55 páginas). https://doi.org/10.1002/wsbm.1537. Factor de impacto: 5.00. Q2.
54. E. Estudillo, A. Jiménez, Pablo E. Bustamante-Nieves, C. Palacios-Reyes, I. Velasco, A. López-Ornelas*. 2021. Cryopreservation of Gametes and Embryos and Their Molecular Changes. Int J Mol Sci 22: 10864 (18 páginas). https://doi.org/10.3390/ijms221910864. Factor de impacto: 5.92. Q1.
53. C. Meléndez-Ramírez, R. Cuevas-Diaz Duran*, T. Barrios-García, M. Giacomán-Lozano, A. López-Ornelas, J. Herrera-Gamboa, E. Estudillo, E. Soto-Reyes, I. Velasco*, V. Treviño*. 2021. Dynamic landscape of chromatin accessibility and transcriptomic changes during differentiation of human embryonic stem cells into dopaminergic neurons. Sci Rep 11: 16977 (18 páginas). doi: 10.1038/s41598-021-96263-1. Factor de impacto: 4.38. Q1.
52. R. Lara-Rodarte, D. Cortés, K. Soriano, F. Carmona, L. Rocha, E. Estudillo, A. López-Ornelas, I. Velasco*. 2021. Mouse Embryonic Stem Cells Expressing GDNF Show Enhanced Dopaminergic Differentiation and Promote Behavioral Recovery After Grafting in Parkinsonian Rats. Front Cell Dev Biol 9: 661656 (14 páginas). doi: 10.3389/fcell.2021.661656. Factor de impacto: 6.68. Q2.
51. J. Romo-Yáñez, G. Rodríguez-Martínez, J. Aragón, L. Siqueiros-Márquez, A. Herrera-Salazar, I. Velasco, C. Montañez*. 2021. Embryonic neural stem/progenitor cells as model to characterize dystrophin and dystrophin-associated proteins expression during neuronal or astrocytic differentiation. MethodsX 8: 101325 (7 páginas). doi: 10.1016/j.mex.2021.101325. Journal Citation Indicator: 0.32. Q2.
50. A. Aguirre-Vázquez, L. A. Salazar-Olivo, X. Flores-Ponce, A. L. Arriaga-Guerrero, D. Garza-Rodríguez, M. E. Camacho-Moll, I. Velasco, F. Castorena-Torres, N. Dadheech, M. Bermúdez de León*. 2021. 5-Aza-2'-Deoxycytidine and Valproic Acid in Combination with CHIR99021 and A83-01 Induce Pluripotency Genes Expression in Human Adult Somatic Cells. Molecules 26: 1909 (12 páginas). doi: 10.3390/molecules26071909. Factor de impacto: 4.41. Q2.
49. A. Tenorio-Mina, D. Cortés, J. Esquivel-Estudillo, A. López-Ornelas, A. Cabrera-Wrooman, R. Lara-Rodarte, I. Escobedo-Avila, F. Vargas-Romero, D. Toledo-Hernández, E. Estudillo, J. J. Acevedo-Fernández, J. Santa-Olalla Tapia*, I. Velasco*. 2021. Human keratinocytes adopt neuronal fates after in utero transplantation in the developing rat brain. Cell Transplant 30: 1-13.. doi: 10.1177/0963689720978219. Factor de impacto: 4.06. Q3.
48. M. J. Castellanos-Montiel, I. Velasco, I. Escodebo-Avila*. 2021. Modeling the neuromuscular junction in vitro: an approach to study neuromuscular junction disorders. Ann NY Acad Sci 1488: 3-15. . doi: 10.1111/nyas.14504. Factor de impacto: 5.69. Q1.
47. J. Romo-Yáñez, G. Rodríguez-Martínez, J. Aragón, L. Siqueiros-Márquez, A. Herrera-Salazar, I. Velasco, C. Montañez*. 2020. Characterization of the expression of dystrophins and dystrophin-associated proteins during embryonic neural stem/progenitor cell differentiation. Neurosci Lett 736: 135247 (6 páginas). doi: 10.1016/j.neulet.2020.135247. Factor de impacto: 2.27. Factor de impacto a 5 años: 3.05. Q3.
46. K. Méndez-Maldonado, G. Vega-López, M. J. Aybar*, I. Velasco*. 2020. Neurogenesis from neural crest cells: molecular mechanisms in the formation of cranial nerves and ganglia. Front Cell Dev Biol 8: 635 (26 páginas). doi: 10.3389/fcell.2020.00635. Factor de impacto: 6.68. Q2.
45. F. Vargas-Romero, R. González-Barrios, L. Guerra-Calderas, I. Escobedo-Avila, D. Cortés-Pérez, A. López-Ornelas, L. Rocha, E. Soto-Reyes*, I. Velasco*. 2019. Histamine Modulates Midbrain Dopamine Neuron Differentiation Through the Regulation of Epigenetic Marks. Front Cell Neurosci. 13: 215 (12 páginas). doi: 10.3389/fncel.2019.00215. Factor de impacto: 5.51. Q1.
44. C. M. Castillo-Bautista, L. W. Torres-Tapia, J. A. Rangel-Méndez, S. R. Peraza-Sánchez, D. Cortés, I. Velasco, R. E. Moo-Puc*. 2019. Neuroprotective effect of Mayan medicinal plant extracts against glutamate-induced toxicity. J Nat Med. 73: 672-678. doi: 10.1007/s11418-019-01284-w. Factor de impacto: 2.34. Q4.
43. K. Méndez-Maldonado, G. Vega-López, S. Caballero-Chacón, M. J. Aybar*, I. Velasco*. 2018. Activation of Hes1 and Msx1 in Transgenic Mouse Embryonic Stem Cells Increases Differentiation into Neural Crest Derivatives. Int J Mol Sci. 19: 4025 (23 páginas). doi: 10.3390/ijms19124025. Factor de impacto: 5.92. Q1.
42. I. Velasco*, T. Kunath, V. Ramos-Mejía, M. A. Velasco-Velázquez. 2017. Editorial for Special Issue. Producing Stem Cell-Based Transplants for Future Therapeutic Purposes. Stem Cells Int, Article ID 9592302, 3 pages. doi: 10.1155/2017/9592302. Factor de impacto: 3.39.
41. D. Cortés, O. A. Carballo-Molina, M. J. Castellaños-Montiel, I. Velasco*. 2017. The non-survival effects of Glial cell line-Derived Neurotrophic Factor on neural cells. Front Mol Neurosci 10: 258 (páginas 1-13). doi: 10.3389/fnmol.2017.00258. Factor de impacto: 4.74.
40. J. Domingo-Reines, A. López-Ornelas, R. Montes, T. Romero, J. L. Rodríguez-Llamas, R. Lara-Rodarte, F. González-Pozas, V. Ayllón, P. Menendez, I. Velasco, V. Ramos-Mejía*. 2017. HoxA9 and EGFP reporter expression in human Embryonic Stem Cells (hESC) as useful tools for studying human development. Stem Cell Res 25: 286-290. doi: 10.1016/j.scr.2017.08.004. Factor de impacto: 3.83.
39. D. Romero-Moya, C. Santos-Ocaña, Julio Castaño, G. Garrabou, J. A. Rodríguez, V. Ruiz-Bonilla, E. Perdiguero, C. Bueno, P. González-Rodriguez, A. Giorgetti, C. Prieto, A. Muñoz-López, D. J. Fernández-Ayala, M. V. Cascajo, I. Velasco, J. López-Barneo, F. Cardellach, R. Artuch, P. Muñoz-Cánoves, P. Navas, P. Menéndez*. 2017. Genetic rescue of mitochondrial and skeletal muscle impairment in an induced Pluripotent Stem Cells model of coenzyme Q10 deficiency. Stem Cells 35: 1687-1703. doi: 10.1002/stem.2634. Factor de impacto: 6.28.
38. D. Cortés, Y. Robledo-Arratia, R. Hernández-Martínez, I. Escobedo-Ávila, J. Bargas, I. Velasco*. 2016. Transgenic GDNF positively influences proliferation, differentiation, maturation and survival of motor neurons produced from mouse embryonic stem cells. Front Cell Neurosci 10: 217 (páginas 1-16). doi: 10.3389/fncel.2016.00217. Factor de impacto: 4.76.
37. O. A. Carballo-Molina, A. Sánchez-Navarro, A. López-Ornelas, R. Lara Rodarte, P. Salazar, A. Campos-Romo, V. Ramos-Mejía, I. Velasco*. 2016. Semaphorin 3C Released from a Biocompatible Hydrogel Guides and Promotes Axonal Growth of Rodent and Human Dopaminergic Neurons. Tissue Eng Part A 22: 850-861. doi: 10.1089/ten.TEA.2016.0008. Factor de impacto: 4.02.
36. V. Palma*, F. J. Pitossi*, S. K. Rehen*, C. Touriño*, I. Velasco*. Stem cell research in Latin America: update, challenges and opportunities in a priority research area. 2015. Regen Med 10: 785-798. doi: 10.2217/rme.15.44. Factor de impacto: 3.21.
35. O. A. Carballo-Molina, I. Velasco*. 2015. Hydrogels as scaffolds and delivery systems to enhance axonal regeneration after injuries. Front Cell Neurosci 9: 13 (páginas 1-12). doi: 10.3389/fncel.2015.00013. Factor de impacto: 4.76.
34. I. Escobedo-Avila, F. Vargas-Romero, A. Molina-Hernández, R. López-González, D. Cortés, J.A. De Carlos, I. Velasco*. 2014. Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors. Mol Brain 7(1): 58 (páginas 1-18). doi: 10.1186/s13041-014-0058-x. Factor de impacto: 4.10.
33. I. Velasco*, P. Salazar, A. Giorgetti, V. Ramos-Mejía, J. Castaño, D. Romero-Moya, P. Menendez*. 2014. Concise Review: Generation of neurons from somatic cells of healthy individuals and neurological patients through induced pluripotency or direct conversion. Stem Cells 32: 2811-2817. doi: 10.1002/stem.1782. Factor de impacto: 6.28.
32. N.E. Díaz-Martínez, E. Tamariz, N.F. Díaz, C.M. García-Peña, A. Varela-Echavarría*, I. Velasco*. 2013. Recovery from Experimental Parkinsonism by Semaphorin-guided Axonal Growth of Grafted Dopamine Neurons. Mol Ther 21: 1579-1591. doi: 10.1038/mt.2013.78. Factor de impacto: 6.83.
31. A. Molina-Hernández, G. Rodríguez-Martínez, I. Escobedo-Avila, I. Velasco*. 2013. Histamine up-regulates Fibroblast Growth Factor Receptor 1 and increases FOXP2 neurons in cultured neural precursors by histamine type 1 receptor activation: conceivable role of histamine in neurogenesis during cortical development in vivo. Neural Dev, 8: 4 (páginas 1-14). doi: 10.1186/1749-8104-8-4. Factor de impacto: 3.05.
