Metástasis: interacciones físicas y funcionales entre células tumorales humanas y células endoteliales.
Caracterización de factores séricos implicados el desarrollo de cáncer de mama en condiciones de obesidad.
Nuevas combinaciones de terapia antitumoral y mecanismos de resistencia asociada.

Publicaciones

1)Flores-García, L. C., Ventura-Gallegos, J. L., Romero-Córdoba, S. L., Hernández-Juárez, A. J., Naranjo-Meneses, M. A., García-García, E., Méndez, J. P., Cabrera-Quintero, A. J., Ramírez-Ruíz, A., Pedraza-Sánchez, S., Meraz-Cruz, N., Vadillo-Ortega, F., & Zentella-Dehesa, A. (2022). Sera from women with different metabolic and menopause states differentially regulate cell viability and Akt activation in a breast cancer in-vitro model. PloS one, 17(4), e0266073. https://doi.org/10.1371/journal.pone.0266073
2)Contreras-Romero, C., Pérez-Yépez, E. A., Martinez-Gutierrez, A. D., Campos-Parra, A., Zentella-Dehesa, A., Jacobo-Herrera, N., López-Camarillo, C., Corredor-Alonso, G., Martínez-Coronel, J., Rodríguez-Dorantes, M., de León, D. C., & Pérez-Plasencia, C. (2022). Gene Promoter-Methylation Signature as Biomarker to Predict Cisplatin-Radiotherapy Sensitivity in Locally Advanced Cervical Cancer. Frontiers in oncology, 12, 773438. https://doi.org/10.3389/fonc.2022.773438
3)Torres-Ruiz, J., Carrillo-Vázquez, D. A., Leal-Alanis, A., Zentella-Dehesa, A., Tapia-Rodríguez, M., Maravillas-Montero, J. L., Nuñez-Álvarez, C. A., Carazo-Vargas, E. R., Romero-Hernández, I., Juárez-Vega, G., Alcocer-Varela, J., & Gómez-Martín, D. (2022). Low-Density Granulocytes and Neutrophil Extracellular Traps as Biomarkers of Disease Activity in Adult Inflammatory Myopathies. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 28(2), e480–e487. https://doi.org/10.1097/RHU.0000000000001772
4)Saldivar-Cerón, H. I., Villamar-Cruz, O., Wells, C. M., Oguz, I., Spaggiari, F., Chernoff, J., Patiño-López, G., Huerta-Yepez, S., Montecillo-Aguado, M., Rivera-Pazos, C. M., Loza-Mejía, M. A., Vivar-Sierra, A., Briseño-Díaz, P., Zentella-Dehesa, A., Leon-Del-Rio, A., López-Saavedra, A., Padierna-Mota, L., Ibarra-Sánchez, M. J., Esparza-López, J., Hernández-Rivas, R., … Arias-Romero, L. E. (2022). p21-Activated Kinase 1 Promotes Breast Tumorigenesis via Phosphorylation and Activation of the Calcium/Calmodulin-Dependent Protein Kinase II. Frontiers in cell and developmental biology, 9, 759259. https://doi.org/10.3389/fcell.2021.759259
5)Esquivel-Chirino, C., Valero-Princet, Y., Gaitán-Cepeda, L. A., Hernández-Hernández, C., Hernández, A. M., Laparra-Escareño, H., Ventura-Gallegos, J. L., Montes-Sánchez, D., Lopéz-Macay, A., Hernández-Sánchez, F., Oliveira, W. A., Morales-González, J. A., Carmona-Ruiz, D., Rosen-Esquivel, K., & Zentella-Dehesa, A. (2021). The Effects of COVID-19 on Healthcare Workers and Non-Healthcare Workers in Mexico: 14 Months into the Pandemic. Medicina (Kaunas, Lithuania), 57(12), 1353. https://doi.org/10.3390/medicina57121353
6) Ochoa-Guzmán, A., Guillén-Quintero, D., Muñoz-Hernández, L., García, A., Díaz-Díaz, E., Pérez-Méndez, O., Rodríguez-Guillén, R., Mitre-Aguilar, I. B., Zentella-Dehesa, A., Aguilar-Salinas, C. A., & Tusié-Luna, M. T. (2021). The influence of high-density lipoprotein (HDL) and HDL subfractions on insulin secretion and cholesterol efflux in pancreatic derived β-cells. Journal of endocrinological investigation, 44(9), 1897–1904. https://doi.org/10.1007/s40618-021-01504-9
7)Bravo-Reyna, C. C., López-Gómez, O., Zentella, A., Guerra-Mora, J. R., Torres-Villalobos, G., Perales-Caldera, E., Frías-Guillén, J., & Granados, J. (2021). Comparison of the Effects of Endotracheal Intubation of Wistar Rats Using the Conventional Technique vs. a New Modified Technique Using a 3D Mouth-Piece. Journal of investigative surgery : the official journal of the Academy of Surgical Research, 34(9), 979–983. https://doi.org/10.1080/08941939.2020.1736217
8) Tejeda, M. E., Canto, P., Tenorio-Torres, A., Orozco-Arguelles, L., Coral-Vázquez, R. M., Zentella-Dehesa, A., Leal-García, M., Vega-García, C. C., Bautista-Piña, V., & Méndez, J. P. (2021). Increased FNDC5/IRISIN protein expression in breast cancer tissue is associated with obesity in postmenopausal women. Journal of clinical pathology, jclinpath-2020-207249. Advance online publication. https://doi.org/10.1136/jclinpath-2020-207249
9) Iglesias, M., Butrón, P., Torre-Villalvazo, I., Torre-Anaya, E. A., Sierra-Madero, J., Rodriguez-Andoney, J. J., Tovar-Palacio, A. R., Zentella-Dehesa, A., Domínguez-Cherit, G., Rodriguez-Reyna, T. S., Granados-Arriola, J., Espisosa-Cruz, V., Téllez-Pallares, F. P., Lozada-Estrada, A., Zepeda Carrillo, C. A., Vázquez-Mézquita, A. J., & Nario-Chaidez, H. F. (2021). Mesenchymal Stem Cells for the Compassionate Treatment of Severe Acute Respiratory Distress Syndrome Due to COVID 19. Aging and disease, 12(2), 360–370. https://doi.org/10.14336/AD.2020.1218
10) Lozano-Corona, R., Laparra-Escareno, H., Anaya-Ayala, J. E., Zentella-Dehesa, A., Baquera-Heredia, J. J., Argüero-Sánchez, R., & Hinojosa, C. A. (2020). Cilostazol as a noninferiority pharmacologic option to paclitaxel in early intimal hyperplasia inhibition after venous balloon angioplasty in a rabbit model: a preliminary study. JVS-vascular science, 1, 200–206. https://doi.org/10.1016/j.jvssci.2020.09.003
11) Cervantes-Badillo, M. G., Paredes-Villa, A., Gómez-Romero, V., Cervantes-Roldán, R., Arias-Romero, L. E., Villamar-Cruz, O., González-Montiel, M., Barrios-García, T., Cabrera-Quintero, A. J., Rodríguez-Gómez, G., Cancino-Villeda, L., Zentella-Dehesa, A., & León-Del-Río, A. (2020). IFI27/ISG12 Downregulates Estrogen Receptor α Transactivation by Facilitating Its Interaction With CRM1/XPO1 in Breast Cancer Cells. Frontiers in endocrinology, 11, 568375. https://doi.org/10.3389/fendo.2020.568375
12) Vargas-Hernández, O., Ventura-Gallegos, J. L., Ventura-Ayala, M. L., Torres, M., Zentella, A., & Pedraza-Sánchez, S. (2020). THP-1 cells increase TNF-α production upon LPS + soluble human IgG co-stimulation supporting evidence for TLR4 and Fcγ receptors crosstalk. Cellular immunology, 355, 104146. https://doi.org/10.1016/j.cellimm.2020.104146
13) Mora-Ramiro, B., Jiménez-Estrada, M., Zentella-Dehesa, A., Ventura-Gallegos, J. L., Gomez-Quiroz, L. E., Rosiles-Alanis, W., Alarcón-Aguilar, F. J., & Almanza-Pérez, J. C. (2020). Cacalol Acetate, a Sesquiterpene from Psacalium decompositum, Exerts an Anti-inflammatory Effect through LPS/NF-KB Signaling in Raw 264.7 Macrophages. Journal of natural products, 83(8), 2447–2455. https://doi.org/10.1021/acs.jnatprod.0c00300
14) Navarrete-Bernal, M., Cervantes-Badillo, M. G., Martínez-Herrera, J. F., Lara-Torres, C. O., Gerson-Cwilich, R., Zentella-Dehesa, A., Ibarra-Sánchez, M. J., Esparza-López, J., Montesinos, J. J., Cortés-Morales, V. A., Osorio-Pérez, D., Villegas-Osorno, D. A., Reyes-Sánchez, E., Salazar-Sojo, P., Tallabs-Utrilla, L. F., Romero-Córdoba, S., & Rocha-Zavaleta, L. (2020). Biological Landscape of Triple Negative Breast Cancers Expressing CTLA-4. Frontiers in oncology, 10, 1206. https://doi.org/10.3389/fonc.2020.01206
15) Ochoa-Guzmán, A., Moreno-Macías, H., Guillén-Quintero, D., Chávez-Talavera, O., Ordoñez-Sánchez, M. L., Segura-Kato, Y., Ortíz, V., Díaz-Díaz, E., Muñoz-Hernández, L., García, A., Pérez-Méndez, O., Zentella-Dehesa, A., Aguilar-Salinas, C. A., & Tusié-Luna, M. T. (2020). R230C but not - 565C/T variant of the ABCA1 gene is associated with type 2 diabetes in Mexicans through an effect on lowering HDL-cholesterol levels. Journal of endocrinological investigation, 43(8), 1061–1071. https://doi.org/10.1007/s40618-020-01187-8
16) Garza-Reyes, M. G., Mora-Ruíz, M. D., Chávez-Sánchez, L., Madrid-Miller, A., Cabrera-Quintero, A. J., Maravillas-Montero, J. L., Zentella-Dehesa, A., Moreno-Ruíz, L., Pastor-Salgado, S., Ramírez-Arias, E., Pérez-Velázquez, N., Chávez-Rueda, A. K., Blanco-Favela, F., Vazquez-Gonzalez, W. G., & Contreras-Rodríguez, A. (2020). Effect of Interleukin-17 in the Activation of Monocyte Subsets in Patients with ST-Segment Elevation Myocardial Infarction. Journal of immunology research, 2020, 5692829. https://doi.org/10.1155/2020/5692829
17) Torres-Ruiz, J., Villca-Gonzales, R., Gómez-Martín, D., Zentella-Dehesa, A., Tapia-Rodríguez, M., Uribe-Uribe, N. O., Morales-Buenrostro, L. E., & Alberú, J. (2020). A potential role of neutrophil extracellular traps (NETs) in kidney acute antibody mediated rejection. Transplant immunology, 60, 101286. https://doi.org/10.1016/j.trim.2020.101286
18) Posadas-Rodríguez, P., Posadas-Rodríguez, N. E., González-Puertos, V. Y., Toledo-Pérez, R., Ventura-Gallegos, J. L., Zentella, A., Gómez-Quiroz, L. E., Königsberg, M., & Luna-López, A. (2020). tBHQ Induces a Hormetic Response That Protects L6 Myoblasts against the Toxic Effect of Palmitate. Oxidative medicine and cellular longevity, 2020, 3123268. https://doi.org/10.1155/2020/3123268
19) Tavarez-Santamaría, Z., Jacobo-Herrera, N. J., Rocha-Zavaleta, L., Zentella-Dehesa, A., Couder-García, B., & Martínez-Vázquez, M. (2020). A Higher Frequency Administration of the Nontoxic Cycloartane-Type Triterpene Argentatin A Improved Its Anti-Tumor Activity. Molecules (Basel, Switzerland), 25(8), 1780. https://doi.org/10.3390/molecules25081780
20) Icaza-Chávez, M. E., Tanimoto, M. A., Huerta-Iga, F. M., Remes-Troche, J. M., Carmona-Sánchez, R., Ángeles-Ángeles, A., Bosques-Padilla, F. J., Blancas-Valencia, J. M., Grajales-Figueroa, G., Hernández-Mondragón, O. V., Hernández-Guerrero, A. I., Herrera-Servín, M. A., Huitzil-Meléndez, F. D., Kimura-Fujikami, K., León-Rodríguez, E., Medina-Franco, H., Ramírez-Luna, M. A., Sampieri, C. L., Vega-Ramos, B., & Zentella-Dehesa, A. (2020). The Mexican consensus on the detection and treatment of early gastric cancer. Consenso mexicano sobre detección y tratamiento del cáncer gástrico incipiente. Revista de gastroenterologia de Mexico (English), 85(1), 69–85. https://doi.org/10.1016/j.rgmx.2019.10.001
21) Couder-García, B., Jacobo-Herrera, N. J., Zentella-Dehesa, A., Rocha-Zavaleta, L., Tavarez-Santamaría, Z., & Martínez-Vázquez, M. (2019). The Phytosterol Peniocerol Inhibits Cell Proliferation and Tumor Growth in a Colon Cancer Xenograft Model. Frontiers in oncology, 9, 1341. https://doi.org/10.3389/fonc.2019.01341
22) Whittall-García, L. P., Torres-Ruiz, J., Zentella-Dehesa, A., Tapia-Rodríguez, M., Alcocer-Varela, J., Mendez-Huerta, N., & Gómez-Martín, D. (2019). Neutrophil extracellular traps are a source of extracellular HMGB1 in lupus nephritis: associations with clinical and histopathological features. Lupus, 28(13), 1549–1557. https://doi.org/10.1177/0961203319883936
23) Jacobo-Herrera N,Pérez-Plasencia C, Castro-Torres VA, Martínez-Vázquez M, González-Esquinca AR, Zentella-Dehesa A. Selective Acetogenins and Their Potential as Anticancer Agents.Front. Pharmacol. 2019. Jul 18; 10:783. FI: 3.845 (ISSN: 1663-9812)
DOI: 10.3389/fphar.2019.00783
24) Cynthia Navarro-Mabarak; Irma Beatriz Mitre-Aguilar; Rafael Camacho Carranza; Clorinda Arias; Alejandro Zentella-Dehesa, Jesús Javier Espinosa-Aguirre. Role of NF-kB in cytochrome P450 epoxygenase down-regulation during an inflammatory process in astrocytes. Nerochem International 2019 Jul 2; 129:104499. F.I. 3.994 (ISSN 0197-0186) Grupo 3 DOI: 10.1016/j.neuint.2019.104499
25) Mitre-Aguilar IB, Barrios-Garcia T, Ruiz-Lopez VM, Cabrera-Quintero AJ, Mejia-Dominguez NR, Ventura-Gallegos JL, Moreno-Mitre D, Aranda-Gutierrez A, Mejia-Rangel J, Escalona-Guzman AR, Chavarri-Guerra Y, Leon-Del-Rio A, Zentella-Dehesa A. (autor correspondiente 17). Glucocorticoid-dependent expression of IAP participates in the protection against TNF-mediated cytotoxicity in MCF7 cells. BMC Cancer. 2019 Mar 31; 19:356. F.I. 3.288 (ISSN 1471-2407) Grupo 3
DOI: 10.1186/s12885-019-5563-y
26) Martín-Manzo MV, Lara C, Vargas-de-Leon C, Carrero J, Queipo G, Fonseca-Sanchez M, Mejia-Dominguez NR, Kershenobich D, Mummidi S, Zentella-Dehesa A, Hernandez J. Interaction of Breast Cancer and Insulin Resistance on PD1 and TIM3 Expression in Peripheral Blood CD8 T Cells. Pathol Oncol Res. 2019 Jul;25(3):1233-1243. F.I. 2.433 (ISSN 1219-4956) Grupo 1 doi: 10.1007/s12253-019-00610-7.
27) Torres-Ruiz J, Mejía-Domínguez NR, Zentella-Dehesa A, Ponce-de-León A, Morales-Padilla SR, Vázquez-Rodríguez R, Alvarado-Lara MR, Reyna-de-la-Garza RA, Tapia-Rodríguez M, Juárez-Vega G, Merayo-Chalico J, Barrera-Vargas A, Alcocer-Varela JC, Gómez-Martín D.The Systemic Lupus Erythematosus Infection Predictive Index (LIPI): A Clinical-Immunological Tool to Predict Infections in Lupus Patients. Front Immunol. 2019. Jan 14; 9:3144. F.I. 4.716 (ISSN 1664-3224) Grupo 3 DOI: 10.3389/fimmu.2018.03144.
28) Damasco Avila, Erika; Ventura Gallegos, José Luis; Guevara Cruz, Martha; Zentella Dehesa, Alejandro. Omega-3 Polyunsaturated Fatty Acids Supplemented Diet and its preventive effect on tumor growth in nude mice Nutr. Clín. Diet. Hosp. 2018; 38(2):16-21 Sin F.I. (ISSN 0211-6057) Grupo 1 DOI: 10.12873/382damasco
29) Rodríguez Bautista R, Ortega Gómez A, Hidalgo Miranda A, Zentella Dehesa A, Villarreal-Garza C, Ávila-Moreno F, Arrieta O. Long non-coding RNAs: implications in targeted diagnoses, prognosis, and improved therapeutic strategies in human non- and triple-negative breast cancer. Clin Epigenetics. 2018;10:88. F.I. 2.90 (ISSN 1868-7083 ) Grupo 1 doi: 10.1186/s13148-018-0514-z. eCollection 2018.
30) De Los Santos S, Palma-Flores C, Zentella-Dehesa A, Canto P, Coral-Vázquez RM. (-)-Epicatechin inhibits development of dilated cardiomyopathy in δ sarcoglycan null mouse. Nutr Metab Cardiovasc Dis. 2018 Nov;28(11):1188-1195. F.I. 3.318 (ISSN 0939-4753) Grupo 1 doi: 10.1016/j.numecd.2018.06.019.
31) Gómez-Sámano MÁ, Baquerizo-Burgos JE, Coronel MFC, Wong-Campoverde BD, Villanueva-Martinez F, Molina-Botello D, Avila-Rojo JA, Palacios-Báez L, Cuevas-Ramos D, Gomez-Perez FJ, Zentella-Dehesa A Aguayo-González Á, Gulias-Herrero A. Effect of imatinib on plasma glucose concentration in subjects with chronic myeloid leukemia and gastrointestinal stromal tumor. BMC Endocr Disord. 2018 Nov 3;18(1):77. F.I. 2.35 (ISSN 1472-6823) Grupo 1 doi: 10.1186/s12902-018-0303-x.
32) Muñoz-Hernández L, Ortiz-Bautista RJ, Brito-Córdova G, Lozano-Arvizu F, Saucedo S, Pérez-Méndez O, Zentella-Dehesa A, DauteuilleC, Lhomme M, Lesnik P, Chapman MJ, Kontush A, Aguilar Salinas CA. Cholesterol efflux capacity of large, small and total HDL particles is unaltered by atorvastatin in patients with type 2 diabetes. Atherosclerosis (2018) 277:72-79. F.I. (ISSN ) Grupo 2. doi.org/10.1016/j.atherosclerosis.2018.08.027
33) Ortega-Pierres G, Argüello-García R, Laredo-Cisneros S, Gómez-Mondragón M, Inzunza-Arroyo R, Ventura-Gallegos JL, Fonseca-Linán R, Flores-Benítez D, Raya-Sandino A, Chávez-Munguía B, Ventura-Gallegos JL, Zentella-Dehesa A, Bermúdez-Cruz RM, González-Mariscal L. Giardipain-1, a protease secreted by Giardia duodenalis trophozoites, causes junctional, barrier and apoptotic damage in epithelial cell monolayers. International Journal of Parasitology (2018) 48:621-639. F.I. 3.730 (ISSN 0020-7519) Grupo 1 DOI: 10.1016/j.ijpara.2018.01.006
34) Contreras Nuñez E, Blancas-Flores G, Cruz M, Almanza-Pérez JC, Gómez-Zamudio JH, Ventura-Gallegos JL, Zentella-Dehesa A, Lazzarini R, Román-Ramos R, Alarcón-Aguilar FJ. Participation of the IKK-a/b complex in the inhibition of thr TNF-a/NF-kB pathwayby glycine: Possible involvment of a membrane receptor specific to adipocytes . Biomedicine & Pharmacotherapy 2018, 102:120-131. F.I. 1.86 (ISSN 0753-3322) Grupo 4 DOI: 10.1016/j.biopha.201803.048.
35) Alma R Escalona-Guzman, Ricardo Hernández-Garcia , Felipe Vadillo-Ortega, Rebeca Lopez-Marure, Janini Mejia-Rangel , Irma B Mitre-Aguilar, Alberto J Cabrera-Quintero, Alejandro Zentella-Dehesa. Effect of soluble factors derived from ZR 75.30 breast cancer cells on endothelial activation. International Journal of Clinical and Experimental Pathology 2018;11(2):685-69. F.I. 1.706 (ISSN:1936-2625) GRUPO 4, DOI: 10.1016/j.jinorgbio.2013.07.004
36) Sánchez-Monroy MB, Jacobo-Herrera NJ, Zentella-Dehesa A, Hernández-Téllez B, Martínez-Vázquez M. Masticadienomic and 3 alpha-OH masticadienoic acids indice apoptosis and inhbit cell proliferation and tumor growth in prostatecancer xenographs in vivo. Molecules 2017, 22(9)pii.E1479. F.I: 2.861 (ISSN 1420-3049). Grupo 4; doi:10.3390/molecules22091479.
37) Martínez-Ramírez I, Del-Castillo-Falconi V, Mitre-Aguilar IB, Amador-Molina A, Carrillo-García A, Langley E, Zentella-Dehesa A, Soto-Reyes E, García-Carrancá A, Herrera LA, Lizano M. . SOX2 as a New Regulator of HPV16 Transcription. Viruses (Basel). 2017 ;9(7). pii: E175. F.I. 3.640 (ISSN 1999-4915). Grupo 4. doi: 10.3390/v9070175.
38) Ramírez-Amador V, Zambrano JG, Anaya-Saavedra G, Zentella-Dehesa A, Irigoyen-Camacho E, Meráz-Cruz N, Ponce de León-Rosales S (2017). TNF as marker of oral candidiasis, HSV infection, and mucositis onset during chemotherapy in leukemia patients. Oral Dis. 2017 ;23(7):941-948. 2017. F.I. 2.31 (ISSN 1354-523X. GRUPO 3. DOI: 10.1111/odi.12677.
39) Juan Carlos Romero-Benavides, Natalia Bailon-Moscoso, Hortensia Parra-Delgado, Maria Isabel Ramirez, Javier Villacis, Henrry Cabrera, Gabriela Gonzalez-Arevalo, Ruth Cueva, Alejandro Zentella-Dehesa, Edward A. Ratovitski, Mariano Martínez-Vázquez. Argentatin B derivatives induce cell cycle arrest and DNA damage in human colon cancer cells through p73/p53 regulatio. Medicinal Chemistry Research, 2017, 27(3):834–843. F.I. 1.23 (ISSN‎: ‎1054-2523) GRUPO 3, Sin DOI:

Circuito de Posgrado, Ciudad Universitaria
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