Modulación por adenosina del metabolismo intermedio, energía metabólica. Caracterización y función de cambio circadiano de adenosina en diferentes tejidos, sangre, hígado, cerebro y corazón.

Publicaciones

1. Pérez-Cabeza de Vaca R, Domínguez-López M, Guerrero-Celis N, Rodríguez-Aguilera JR, Chagoya de Sánchez V. Inflammation is regulated by the adenosine derivative molecule, IFC-305, during reversión of cirrosis in a CCl4 rat model. International Immunopharmacology, 2018 54:12-23. FI 4.8

2. Lozano-Rosas, M.G., Chávez, E., Aparicio Cadena, A.R., Velasco-Loyden, G., Chagoya de Sánchez, V. Mitoepigenetics and hepatocellular carcinoma. Hepatoma Res, 4: Art. No. 19, Jun 2018. FI 1.7

3. Chagoya de Sánchez, V., E. Chávez, G. Velasco-Loyden, M.G. Lozano-Rosas and A. R. Aparicio-cadena. Cap. 8. Interaction of mitochondrial and epigenetic regulation in hepatocelular carcinoma. Pgs. 139-157. In Liver Cancer, Ed. Ahmed Lasfar. IntechOpen. (2018). ISBN: 978-1-78984-448-1 Online: ISBN: 978-1-78984-449-8.

4. Rodríguez-Aguilera, J.R., Pérez-Cabeza de Vaca, R., Guerrero-Celis, N., Velasco-Loyden, G., Domínguez-López, M., Recillas-Targa, F. and Chagoya de Sánchez, V. Cap. 6. Molecular and Cellular Aspects of Cirrhosis and How an Adenosine Derivative Could Revert Fibrosis. Pgs. 99-120. In: Liver Cirrhosis, Debates and Current Challenges, Ed. Georgios Tsoulfas. IntechOpen. (2019). ISBN: 978-1-78923-885-3 Online: 978-1-78923-886-0.

5. Lozano-Rosas, M.G., Chávez, E., Velasco-Loyden, G., Domínguez-López, M., Martínez-Pérez, L. and Chagoya de Sánchez, V. Diminished S-adenosylmethionine biosynthesis and its metabolism in a model of hepatocellular carcinoma is recuperated by an adenosine derivative. Cancer Biology & Therapy, 21(1):81-94, 2020. FI 4.32

6- Enrique Chávez, Gabriela Velasco-Loyden, María Guadalupe Lozano-Rosas, Beatriz Aguilar-Maldonado, Gabrie Muciño-Hernández, Susa Castro Obregón, Victoria Chagoya de Sánchez. Role of autophagy in the chemopreventive effect of the IFC-305 compound in the sequential model of cirrosis-hepatocelluar carcinoman the rat and in vitro. American Journal of Cancer Research, 10(6):1844-1856, 2020. Doi: 10.1124/jpet.116. 239301. FI 3.6

7. Díaz-Rivera, A., Meza-Rios, A., de Sánchez, V.C., Velasco-Loyden, G., García-Benavides, L., Jave-Suárez, L.F., Monroy-Ramírez, H.C., Santos-García, A., Armendáriz-Borunda, J., Sandoval-Rodríguez, A. Hydrodynamics-based liver transfection achieves gene silencing of CB1 using short hairpin RNA plasmid in cirrhotic rats. PloS ONE, 15(2): Art. No. e0228729, Feb 2020. FI 2.9

8. Rodríguez-Aguilera, J.R., Ecsedi, S., Goldsmith, C., Cros, M.-P., Domínguez-López, M., Guerrero-Celis, N., Pérez-Cabeza de Vaca, R., Chemin, I., Recillas-Targa, F., Chagoya de Sánchez, V., Hernández-Vargas H. Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor. Scientific Reports, 10(1): Art. No. 7822, Dec 2020. FI 3.8

9. Goldsmith, C., Rodríguez-Aguilera, J.R., El-Rifai, I., Jarretier-Yuste, A., Hervieu, V., Raineteau, O., Saintigny, P., Chagoya de Sánchez, V., Dante, R., Ichim, G., Hernandez-Vargas, H. Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level. Scientific Reports, 11(1): Art. No. 8032, Dec 2021. FI 3.8

10. Rebeca Pérez-Cabeza De Vaca, Balasubramaniyan Vairappan, Tomás Cortés Espinoza, Juan Antonio Suárez Cuenca, Cuauhtémoc Licona Cassani, Brenda Maldonado Arriaga, Chrisitan Navarro Gerrard, Diana Selene Morgan Penagos, Paul Mondragón Terán and Victoria Chagoya De Sánchez. Cap. Spontaneous Bacterial Peritonitis: Physiopathological Mechanism and Clinical Manifestations. Pgs. 175-191. In: Advances in Hepatology. Rodrigo, L., Martin, I. Guo, X. and Qi, X. Eds. Pub. IntechOpen, 2021. pISBN: 978-1-83968-623-8. eISBN: 978-1-83968-625-2.

11. Luis-García, E.R., Becerril, C., Salgado-Aguayo, A., Aparicio-Trejo, O.E., Romero, Y., Flores-Soto, E., Mendoza-Milla, C., Montaño, M., Chagoya, V., Pedraza-Chaverri, J., El Hafidi, M., Orozco-Ibarra, M. Mitochondrial dysfunction and alterations in mitochondrial permeability transition pore (mPTP) contribute to apoptosis resistance in idiopathic pulmonary fibrosis fibroblasts. International Journal of Molecular Sciences, 22(15): Art. No. 7870, Aug 2021. FI 4.9

12. Guerrero-Escalera, D., Alarcón-Sánchez, B.R., Arellanes-Robledo, J., Cruz-Rangel, A. del Pozo-Yauner, L., Chagoya de Sánchez, V., Resendis-Antonio, O., Villa-Treviño, S., Torres-Mena, J.E., Pérez-Carreón, J.I. Comparative subcellular localization of NRF2 and KEAP1 during the hepatocellular carcinoma development in vivo. BBA – Molecular Cell Research, 1869(5): Art. No. 119222, May 2022. FI 2.44

13. Tecalco-Cruz, A.C., Velasco-Loyden, G., Robles-Villarruel, L., Cortes-González, C.C., Zepeda-Cervantes, J., Pineda, B. and Chagoya de Sánchez, V. Interferon-stimulated gene 15 and ISGylation are upregulated in glioblastoma. Biochemical and Biophysical Research Communications, 621:144-150, Sep 2022. FI 2.5

14. Flores-Mireles, D., Camacho-Villasana, Y., Lutikurti, M., García-Guerrero, A.E., Lozano-Rosas, G., Chagoya, V., Gutiérrez-Cirlos, E.B., Brandt, U., Cabrera-Orefice, A. and Pérez-Martínez, X. The cytochrome b carboxyl terminal region is necessary for mitochondrial complex III assembly. Life Science Alliance, 6(7): Art. No. e202201858, Jul 2023. FI 3.3

15. Domínguez-López, M., Pérez-Cabeza de Vaca, R., Rodríguez-Aguilera, J.R., Guerrero-Celis, N., Velasco-Loyden, G. and Chagoya de Sánchez, V. Liver fibrotic development is reduced through inflammation prevention by an adenosine derivative compound. Biomedicine & Pharmacotherapy, 165: Art. No. 115216, Sep 2023. FI 6.9

16. Chávez, E., Aparicio-Cadena, A.R., Velasco-Loyden, G., Lozano-Rosas, M.G., Domínguez-López, M., Cancino-Bello, A., Torres, N., Tovar, A.R., Cabrera-Aguilar, A. and Chagoya de Sánchez, V. An adenosine derivative prevents the alterations observed in metabolic syndrome in a rat model induced by a rich high-fat diet and sucrose supplementation. PLoS ONE, 18(10): Art No. e 0292448, Oct 2023.

17. García-Carrillo, R., Molina-Pelayo, F.A., Zarate-Lopez, D., Cabrera-Aguilar, A., Ortega-Domínguez, B., Domínguez-López, M., Chiquete Felix, N., Dagnino-Acosta, A., Velasco-Loyden, G., Chávez, E., Castro-Sánchez, L. and Chagoya de Sánchez, V. An adenosine derivative promotes mitochondrial supercomplexes reorganization and restoration of mitochondria structure and bioenergetics in a diethylnitrosamine-induced hepatocellular carcinoma model. Scientific Reports, 14: Art. No. 6348, Mar 2024. FI 3.8

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx