Estudios del reconocimiento molecular en GTPasas que participan en la biogénesis ribosomal.

Caracterización bioquímica de la GTPasa EFL1 y su interacción con la proteína mutada en el Síndrome de Shwacham-Diamond.

Cristalización de proteínas por métodos no convencionales. Efecto de los campos magnéticos y eléctricos en la cristalización de proteínas.

Estudios bioquímicos de proteínas de origen marino.

Publicaciones

Jesús Pérez-Juárez, Juana Virginia Tapia-Vieyra, Gabriel Gutiérrez-Magdaleno and Nuria Sánchez-Puig* (2022) Altered conformational landscape upon sensing guanine nucleotides in a disease mutant of Elongation Factor-like 1 (EFL1) GTPase. Biomolecules 12(8), 1141.
DOI: 10.3390/biom12081141
Impact Factor: 6.06

Sara Restrepo-Pineda, Nuria Sánchez-Puig, Nestor O. Pérez, Enrique García-Hernández, Norma A. Valdez-Cruz and Mauricio A. Trujillo-Roldán* (2022) The pre-induction temperature affects recombinant HuGM-CSF aggregation in thermoinducible Escherichia coli. Applied Microbiology and Biotechnology. 106(8):2883-2902
DOI: 10.1007/s00253-022-11908-z
Impact Factor: 5.0

Alfonso Méndez-Godoy, Daniel García-Montalvo, León P.Martínez-Castilla and Nuria Sánchez-Puig* (2021) Evolutionary and functional relationships in the ribosome biogenesis SBDS and EFL1 protein families. Molecular Genetics and Genomics 296(6):1263-1278
DOI: 10.1007/s00438-021-01814-w
Impact factor 3.3

Abril Gijsbers, Vanesa Vinciauskaite, Axel Siroy, Ye Gao, Giancarlo Tria, Anjusha, Mathew, Nuria Sánchez-Puig, Carmen López-Iglesias, Peter J. Peters and Raimond Ravelli (2021) Priming mycobacterial ESX-secreted protein B to form a channel-like structure. Current Research in Structural Biology 3:153-164
DOI: 10.1016/j.crstbi.2021.06.001
Impact factor 2.8

Nuria Sánchez-Puig*, Mayra Cuéllar-Cruz, Selene R. Islas, Juana V. Tapia-Vieyra, Roberto A. Espinosa and Abel Moreno* (2021) The influence of silicateins on the shape and crystalline habit of silica carbonate biomorphs of alkaline metals (Ca, Ba, Sr). Crystals 11(4):438
DOI: 10.3390/cryst11040438
Impact factor: 2.5

Abril Gijsbers, Nuria Sánchez-Puig, Ye Gao, Peter J. Peters, Raimond B. G. Ravelli and Dritan Siliqi. (2021) Structural characterisation of the partially disordered protein EspK from Mycobacterium tuberculosis. Crystals 11(1):18
DOI: 10.3390/cryst11010018
Impact factor 2.5

Juliana Jaramillo Ramírez, Nancy Marcial-Bazaldua and Nuria Sánchez-Puig*. (2021) Characterisation of the interaction of guanine nucleotides with ribosomal GTPase Lsg1. BBA – Proteins and Proteomics 1869:140538.
DOI: 10.1016/j.bbapap.2020.140538
Impact factor 2.4

Mayra Cuéllar-Cruz, Dieter Schneider, Vivian Stojanoff, Selene R. Islas, Nuria Sánchez-Puig, Roberto Arreguín-Espinosa, José Miguel Delgado and Abel Moreno*. (2020) Formation of crystalline silica-carbonate biomorphs of alkaline Earth metals (Ca, Ba, Sr) from ambient to low temperatures: Chemical implications during the primitive Earth´s life. Crystal Growth and Design, 20:1186-1195.
DOI: 10.1021/acs.cgd.9b01473
Impact Factor 4.1

Pietro Delre, Domenico Alberga, Abril Gijsbers, Nuria Sánchez-Puig, Orazio Nicolotti, Michele Saviano, Dritan Siliqi* and Giuseppe Felice Mangiatordi*. (2020) Exploring the role of Elongation Factor-Like 1 (EFL1) in Shwachman-Diamond Syndrome through molecular dynamics. Journal of Biomolecular Structure and Dynamics, 38:17, 5219-5229
DOI: 10.1080/07391102.2019.1704883
Impact Factor 3.3

Axel Luviano, Roberto Cruz-Castañeda, Nuria Sánchez Puig* and Enrique García Hernández*. (2019) Cooperative energetic effects elicited by the yeast Shwachman-Diamond syndrome protein (Sdo1) and guanine nucleotides modulate the complex conformational landscape of the elongation factor-like 1 (Efl1) GTPase. Biophysical Chemistry, 247: 13-24
DOI: 10.1016/j.bpc.2019.02.003
Impact factor: 1.9

Abril Gijsbers, Diana Carolina Montagut, Alfonso Méndez-Godoy, Davide Altamura, Michele Saviano, Dritan Siliqi and Nuria Sánchez-Puig*. (2018) Interaction of the GTPase Elongation Factor Like-1 with the Shwachman-Diamond Syndrome protein and its missense mutations. International Journal of Molecular Sciences, 19:4012.
DOI:10.3390/ijms19124012
Impact Factor: 4.2

Dritan Siliqi*, James Foadi, Marco Mazzorana, Davide Altamura, Alfonso Méndez-Godoy and Nuria Sánchez-Puig*. (2018) Conformational flexibility of proteins involved in ribosome biogenesis: investigations via Small Angle X-ray Scattering (SAXS). Crystals, 8(3)109.
DOI:10.3390/cryst8030109
ISSN: 2073-4352
Impact Factor: 1.6

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx