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Tutores

GERARDO ALFONSO CORZO BURGUETE

Instituto de Biotecnología (IBT)

Contacto

Teléfono: 777 3291602
Email: corzo@ibt.unam.mx
Sitio web: Visitar sitio web

Campos de conocimiento

Bioquímica
Biotecnología
Reconocimiento Molecular y Bioestructura

Líneas de investigación

Toxinas e interacción farmacológica
Expresión de proteínas en sistemas heterólogos

Publicaciones

Cruz-Orozco,K., Ibarra-Valencia,M.A., Barrios-Camacho,H., Corzo-Burguete,G., Arenas-Sosa,I. (2025). Antimicrobial and Antibiofilm Activity of Analogous Synthetic Peptides from Anoplin, Temporin, and Aurein. International Journal of Peptide Research and Therapeutics, 31 (2), 25.
Open Access Artículo
Mata de los Rios,N., Gastelum-Arellanez,A., Clement,H., Alvarez-Cruz,K., Romero-Terrazas,D., Alvarado-Gonzalez,C., Hinojos-Gallardo,L.C., Corzo,G., Espino-Solis,G.P. (2025). Ion-Channel-Targeting Scorpion Recombinant Toxin as Novel Therapeutic Agent for Breast Cancer. Toxins (Basel), 17 (4), 166.
Artículo
Montero-Dominguez,P.A., Restano-Cassulini,R., Magana-Avila,L.C., Almanza,A., Mercado,F., Corzo,G. (2025). Design of antinociceptive peptide by grafting domains between scorpion B -neurotoxins. Bioorganic Chemistry, 162, 108592.
Artículo
Moran-Gonzalez,M., Acosta de Patino,H., Corzo,G., Romero,E., Gomez-Leija,L. (2025). Evaluation of some blood chemistry parameters caused by different venom doses of Tityus and Centruroides scorpion species from Panama. Toxicon, 258, 108331.
Artículo
Samudio,O., Hernandez-Ortiz,M., Clement,H., Encarnacion,S., Cleghorn,J., Acosta,H., Corzo,G., Salazar,M.H. (2025). Revisiting toxins with transcriptomics-informed proteomics of venom glands and crude venom from Centruroides bicolor from Panama. Journal of Proteomics, 316, 105415.
Artículo
Adame,M., Vazquez,H., Juarez-Lopez,D., Corzo,G., Amezcua,M., Lopez,D., Gonzalez,Z., Schcolnik-Cabrera,A., Morales-Martinez,A., Villegas,E. (2024). Expression and characterization of scFv-6009FV in Pichia pastoris with improved ability to neutralize the neurotoxin Cn2 from Centruroides noxius. International Journal of Biological Macromolecules, 275 (1), 133461.
Artículo
Carpanta,V., Clement,H., Arenas,I., Corzo,G. (2024). A consensus recombinant elapid long-chain a-neurotoxin and how protein folding matters for antibody recognition and neutralization of elapid venoms. Biochemical and Biophysical Research Communications, 732, 150420.
Artículo
Franco-Vasquez,A.M., Lazcano-Perez,F., Mejia-Sanchez,M.A., Corzo,G., Zamudio,F., Carbajal-Saucedo,A., Roman-Gonzalez,S.A., Gomez-Manzo,S., Arreguin-Espinosa,R. (2024). Structural, biochemical and immunochemical characterization of an acidic phospholipase A2 from Lachesis acrochorda (Viperidae: Crotalinae) venom. Toxicon, 237, 107528.
Artículo
Lino-Lopez,G.J., Ruiz-May,E., Elizalde-Contreras,J.M., Jimenez-Vargas,J.M., Rodriguez-Vazquez,A., Gonzalez-Carrillo,G., Bojorquez-Velazquez,E., Garcia-Villalvazo,P.E., Bermudez-Guzman,M.J., Zatarain-Palacios,R., Vazquez-Vuelvas,O.F., Valdez-Velazquez,L.L., Corzo,G. (2024). Proteomic Analysis of Heloderma horridum horridum Venom: Assessment to Its Transcriptome and Newfound Proteins. Journal of Proteome Research, 23 (8), 3638?3648.
Open Access Artículo
Mendoza-Tobar,L.L., Clement,H., Arenas,I., Guerrero-Vargas,J.A., Sepulveda-Arias,J.C., Corzo,G. (2024). An overview of some enzymes from buthid scorpion venoms from Colombia: Centruroides margaritatus, Tityus pachyurus and Tityus n. sp. aff. Metuendus. Journal of Venomous Animals and Toxins including Tropical Diseases., 30.
Articulo
Mendoza-Tobar,L.L., Clement,H., Arenas,I., Guerrero-Vargas,J.A., Hernandez-Orihuela,L., Cardoso-Arenas,S., Sepulveda-Arias,J.C., Corzo,G. (2024). Antimicrobial, toxicological, and antigenic characteristics of three scorpion venoms from Colombia: Centruroides margaritatus, Tityus pachyurus and Tityus n. sp. aff. metuendus. Acta Tropica, 252, 107134.
Open Access Artículo
Munoz-Perez,G.A., Guillen-Chable,F.A., Corzo,G., Arenas-Sosa,I., Sanchez-Cach,L.A., Estrada,G. (2024). Antibacterial activity improvement in a point mutant K45E of the pepper defensin J1-1. Journal of Plant Protection Research, 64 (4), 287-297.
Open Access Artículo
Padilla-Villavicencio,M., Corzo,G., Guillen-Navarro,K., Ibarra-Nunez,G., Arenas,I., Zamudio,F., Diego-Garcia,E. (2024). Cupiennius spiders (Trechaleidae) from southern Mexico: DNA barcoding, venomics, and biological effect. Journal of Venomous Animals and Toxins Including Tropical Diseases, 30, e20230098.
Open Access Artículo
Rodriguez-Vargas,A., Franco-Vasquez,A.M., Triana-Ceron,M., Alam-Rojas,S.N., Escobar-Wilches,D.C., Corzo,G., Lazcano-Perez,F., Arreguin-Espinosa,R., Ruiz-Gomez,F. (2024). Immunological Cross-Reactivity and Preclinical Assessment of a Colombian Anticoral Antivenom against the Venoms of Three Micrurus Species. Toxins (Basel), 16 (2), 104.
Open Access Artículo
Zdenek,C.N., Cardoso,F.C., Robinson,S.D., Mercedes,R.S., Raidjoe,E.R., Hernandez-Vargas,M.J., Jin,J.Y, Corzo,G., Vetter,I, King,G.F., Fry,B.G., Walker,A.A. (2024). Venom exaptation and adaptation during the trophic switch to blood-feeding by kissing bugs. iScience, 27 (9), 110723.
Open Access Artículo
Alvarado-Gonzalez,C., Clement,H., Ballinas-Casarrubias,L., Escarcega-Avila,A., Arenas-Sosa,I., Lopez-Contreras,K.S., Zamudio,F., Corzo,G., Espino-Solis,G.P. (2023). Identification and Venom Characterization of Two Scorpions from the State of Chihuahua Mexico: Chihuahuanus coahuliae and Chihuahuanus crassimannus. Toxins (Basel), 15 (7), 416.
Open Access Artículo
Clement,H., Corrales-Garcia,L.L., Rivas-Mercado,E., Garza-Ocanas L., Corzo,G. (2023). cDNA Cloning, Heterologous Expression, Cytotoxicity, and Inhibitory Effects of a Disintegrin from Bothrops ammodytoides Venom. International Journal of Peptide Research and Therapeutics, 29 (4), 54.
Artículo
Ibarra-Vega,R., Jimenez-Vargas,J.M., Pineda-Contreras,A., Martinez-Martinez,F.J., Barajas-Saucedo,C.E., Garcia-Ortega,H., Magana-Vergara,N.E., Possani,L.D., Corzo,G., Gaitan-Hinojosa,M.A., Vazquez-Vuelvas,O.F., Zamudio,F., Valdez-Velazquez,L.L. (2023). Indolealkylamines in the venom of the scorpion Thorellius intrepidus. Toxicon, 233, 107232.
Revisión
Juarez-Lopez,D., Morales-Ruiz,E., Herrera-Zuniga,L.D., Gonzalez-Carrera,Z., Cuevas-Reyes,E., Corzo,G., Schcolnik-Cabrera,A., Villegas,E. (2023). The resilience of Pseudomonas aeruginosa to antibiotics, and the designing of antimicrobial peptides to overcome microbial resistance. Current Medicinal Chemistry, 30 (1), 72-103.
Artículo
Montero-Dominguez,P.A., Corzo,G. (2023). Characterization of the coupling mechanism of scorpion B -neurotoxins on the voltage-gated sodium channel hNav1.6. Journal of Biomolecular Structure and Dynamics, 41 (23), 14419-14427 .
Artículo
Salazar,M.H., Ortiz,M.H., Encarnacion,S., Zamudio,F., Possani,L.D., Cleghorn,J., Moran,M., Acosta,H., Corzo,G. (2023). A proteomic overview of the major venom components from Tityus championi from Panama. Toxicon, 227, 107082.
Open Access Artículo
Vasquez-Escobar,J., Benjumea-Gutierrez,D.M., Lopera,C., Clement,H.C., Bolanos,D.I., Higuita-Castro,J.L., Corzo,G.A., Corrales-Garcia,L.L. (2023). Heterologous Expression of an Insecticidal Peptide Obtained from the Transcriptome of the Colombian Spider Phoneutria depilate. Toxins (Basel), 15 (7), 436.
Open Access Artículo
Cardoso-Arenas,S., Clement,H., Arenas,I., Olvera,F., Caliskan,F., Corrales-Garcia,L.L., Corzo,G. (2022). Recombinant expression and antigenicity of two peptide families of neurotoxins from Androctonus sp. Journal of Venomous Animals and Toxins Including Tropical Diseases, 28, e20220026.
Open Access Artículo
Mejia-Sanchez,M.A., Clement, H., Corrales-Garcia,L.L., Olamendi-Portugal,T., Carbajal,A., Corzo,G. (2022). Crotoxin B: Heterologous Expression, Protein Folding, Immunogenic Properties, and Irregular Presence in Crotalid Venoms. Toxins, 14 (6), 382.
Open Access Artículo
Rodriguez-Vargas,A., Vega,N., Reyes-Montano,E., Corzo,G., Neri-Castro,E., Clement,H., Ruiz-Gomez,F. (2022). Intraspecific Differences in the Venom of Crotalus durissus cumanensis from Colombia. Toxins, 14 (8), 532.
Open Access Artículo
Salazar,M.H., Clement,H., Corrales-Garcia,L.L., Sanchez,J., Cleghorn,J., Zamudio,F., Possani,L.D., Acosta,H., Corzo,G. (2022). Heterologous expression of four recombinant toxins from Panamanian scorpions of the genus Tityus and Centruroides for production of antivenom. Toxicon: X, 13, 100090.
Open Access Artículo
Santana,F.L., Estrada,K., Alford,M.A., Wu,B.C., Dostert,M., Pedraz,L., Akhoundsadegh,N., Kalsi,P., Haney,E.F., Straus,S.K., Corzo,G., Hancock,R.E.W. (2022). Novel Alligator Cathelicidin As-CATH8 Demonstrates Anti-Infective Activity against Clinically Relevant and Crocodylian Bacterial Pathogens. Antibiotics (Basel), 11 (11), 1603.
Open Access Artículo
Tuxpan-Perez,A., Ibarra-Valencia,M.A., Estrada,B.E., Clement,H., Corrales-Garcia,L.L., Espino-Solis,G.P., Corzo,G. (2022). Antimicrobial and Immunomodulatory Effects of Selected Chemokine and Antimicrobial Peptide on Cytokine Profile during Salmonella Typhimurium Infection in Mouse. Antibiotics, 11 (5), 607.
Open Access Artículo
Vasquez-Escobar,J., Romero-Gutierrez,T., Morales,J.A., Clement,H.C., Corzo,G.A., Benjumea,D.M., Corrales-Garcia,L.L. (2022). Transcriptomic Analysis of the Venom Gland and Enzymatic Characterization of the Venom of Phoneutria depilata (Ctenidae) from Colombia. Toxins, 14 (5).
Open Access Artículo
Alvarado,D., Cardoso-Arenas,S., Corrales-Garcia,L.L., Clement,H., Arenas,I., Montero-Dominguez,P.A., Olamendi-Portugal,T., Zamudio,F., Agota,C., Borrego,J., Panyi,G., Papp,F., Corzo,G. (2021). A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5. Frontiers in Pharmacology, 11, 563858.
Artículo
Archundia,I.G., de la Rosa,G., Olvera,F., Calderon,A., Benard-Valle,M., Alagon,A., Corzo,G. (2021). Assessment of neutralization of Micrurus venoms with a blend of anti-Micrurus tener and anti-ScNtx antibodies. Vaccine, 39 (6), 1000-1006.
Open Access Artículo
Ibarra-Valencia,M.A., Espino-Solis,G.P., Estrada,B.E., Corzo,G. (2021). Immunomodulatory Responses of Two Synthetic Peptides against Salmonella Typhimurium Infection. Molecules, 26 (18), 5573.
Artículo
Jimenez-Vargas,J.M., Ramirez-Carreto,S., Corzo,G., Possani,L.D., Becerril,B., Ortiz,E. (2021). Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus. Peptides, 141, 170553.
Revision
Santana,F.L., Estrada,K., Ortiz,E., Corzo,G. (2021). Reptilian beta-defensins: expanding the repertoire of known crocodylian peptides. Peptides, 136, 170473.
Open Access Artículo
Santana,F.L., Arenas,I., Haney,E.F., Estrada,K., Hancock,R.E.W., Corzo,G. (2021). Identification of a crocodylian ×ý-defensin variant from Alligator mississippiensis with antimicrobial and antibiofilm activity. Peptides, 141, 170549.
Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx
UNAM Posgrado