Contacto
Campos de conocimiento
Biología Molecular y Celular de Microorganismos, Plantas y Animales
Genética y Fisiología Celular
Líneas de investigación
Patogénesis de enfermedades autoinmunes
Mecanismos de tolerancia periférica
Inmunología del cáncer
Genética funcional en inmunología
Perfil en YouTube: @mdcbq_unam
https://www.youtube.com/watch?v=JEPFh6KMPoQ
Publicaciones
1. Flores-Mendoza G, Sansón SP, Rodríguez-Castro S, Crispín JC, Rosetti F. Mechanisms of Tissue Injury in Lupus Nephritis. Trends Mol Med 2018 Apr;24(4):364-378. doi: 10.1016/j.molmed.2018.02.003. FI: 15.2
2. Madera-Salcedo IK, Sánchez-Hernández BE, Svyryd Y, Esquivel-Velázquez M, Rodríguez-Rodríguez N, Trejo-Zambrano MI, García-González HB, Hernández-Molina G, Mutchinick OM, Alcocer-Varela J, Rosetti F, Crispín JC.PPP2R2B hypermethylation causes acquired apoptosis deficiency in systemic autoimmune diseases. JCI Insight 2019 Jul 23;5(16): e126457. doi: 10.1172/jci.insight.12645. FI: 8.3
3. Rosetti F, de la Cruz A, Crispín JC. Gene function studies in systemic lupus erythematosus. Curr Opin Rheumatol 2019; 31: 185-192.3. FI: 4.9
4. Rodríguez-Rodríguez N, Madera-Salcedo IK, Bugarin-Estrada E, Sánchez-Miranda E, Torres-García D, Cervantes-Torres J, Fragoso G, Rosetti F, Crispín JC, Sciutto E. The helminth-derived peptide GK-1 induces an anti-tumoral CD8 T cell response associated with downregulation of the PD-1/PD-L1 pathway. Clin Immunol 2020 Mar; 212: 108240. doi: 10.1016/j.clim.2019.07.006. FI: 10.2
5. Rodríguez-Rodríguez N, Flores-Mendoza G, Apostolidis SA, Rosetti F, Tsokos GC, Crispín JC. TCR-α/β CD4- CD8- double negative T cells arise from CD8+ T cells. J Leukoc Biol 2020 Feb 13. doi: 10.1002/JLB.1AB0120-548R. FI: 6.0
6. Meidan E, Li H, Pan W, Kono M, Yu S, Kyttaris VC, Ioannidis C, Rodriguez Rodriguez N, Crispin JC, Apostolidis SA, Lee P, Manis J, Sharabi A, Tsokos MG, Tsokos GC. Serine/threonine phosphatase PP2A is essential for optimal B cell function. JCI Insight 2020 Mar 12;5(5):e130655. doi: 10.1172/jci.insight.130655. FI: 8.3
7. Rodríguez-Rodríguez N, Madera-Salcedo IK, Cisneros-Segura JA, García-González HB, Apostolidis SA, Saint-Martin A, Esquivel-Velázquez M, Nguyen T, Romero-Rodríguez DP, Tsokos GC, Alcocer-Varela J, Rosetti F, Crispin JC. Protein phosphatase 2A B55ß limits CD8 T cell lifespan following cytokine withdrawal. J Clin Invest. 2020 Aug 4:129479. doi: 10.1172/JCI129479. FI: 19.4
8. Tapia-Maltos MA, Treviño-Frenk I, García-González HB, Rosetti M, Barriga-Maldonado V, Morales-Ramírez F, López-Hernández DC, Rosetti F, Crispín JC. Identification of regulatory T cell molecules associated with severity of multiple sclerosis. Mult Scler 2020 Dec 10. doi: 10.1177/1352458520977045. FI: 5.8
9. Flores-Mendoza G, Rodríguez-Rodríguez N, Rubio RM, Madera-Salcedo IK, Rosetti F, Crispín JC. Fas/FasL Signaling Regulates CD8 Expression During Exposure to Self-Antigens. Front Immunol 2021 Mar 24;12: 635862. doi: 10.3389/fimmu.2021.635862. FI: 8.8
10. Rosetti F, Madera-Salcedo IK, Rodríguez-Rodríguez N, Crispín JC. Regulation of Activated Lymphocyte Survival in Systemic Autoimmunity. Nature Rev Rheumatol 2022; 18(4): 232-244. doi: 10.1038/s41584-021-00741-9. FI: 32.28
