Tutores

Campos de conocimiento

Restablecimiento de los efectos antitumorales de la terapia hormonal en cáncer de mama receptor de estrógenos negativo.
Efectos del calcitriol en la regulación de citocinas proinflamatorias en células de cáncer de mama.
Efecto de los antiestrógenos en la expresión de Musashi en cáncer de mama.

1. Zárate-Pérez A, Cruz-Cázares AP, Ordaz-Rosado D, García-Quiroz J, León-Del-Rio A, Avila E, Milo-Rocha E, Díaz L, García-Becerra R. (corresponding author) The vitamin D analog EB1089 sensitizes triple-negative breast cancer cells to the antiproliferative effects of antiestrogens. Adv Med Sci. 69 (2024) 398406: 398-406. 2024. FI: 2.5
2. Mercado-Sánchez I, López J, Chávez-Rocha R, Vargas-Rodríguez I, Bazán-Jiménez A, Segovia-Mendoza M, Prado-Garcia H, Vázquez MA, García-Becerra R, Garcia-Revilla M. (corresponding author) Evaluation of doxorubicin and β-lapachone analogs as anticancer agents, a biological and computational study. Chemical Biology & Drug Design, 104 (e14596): 1-19. 2024. FI: 3.2
3. Barón-Mendoza I, Martínez-Marcial M, García-Juárez M, Mejía-Hernández M, Cortés-Sánchez Y, Zamora-Sánchez CJ, García-Rebollar JO, Chavira-Ramírez R, Ordaz-Rosado D, Camacho-Arroyo I, Tecamachalzi-Silvarán MB, Montes-Narváez O, González-Flores O, García-Becerra R, González-Arenas A. Disruptions in reproductive health, sex hormonal profiles, and hypothalamic hormone receptors content in females of the C58/J mouse model of autism. Horm Behav, 164(105593):1-10. 2024. FI: 2.5.
4. García-Uribe PÁ, Hernández-Silva G, Vega CC, Ordaz-Rosado D, Morales A, Hernández-Pando R, García-Becerra R, Díaz L, García-Quiroz J, Barrera D, Chirinos M, Larrea F. In Vitro Human Endometrial Cells and In Vivo Rat Model Studies Suggest That Ulipristal Acetate Impacts Endometrial Compatibility for Embryo Implantation. Arch Med Res. 19 (103026):1-11. 2024. FI: 4.7.
5. Achounna AS, Ordaz-Rosado D, García-Quiroz J, Morales-Guadarrama G, Milo-Rocha E, Larrea F, Díaz L, García-Becerra R. (corresponding author) EB1089 Increases the Antiproliferative Response of Lapatinib in Combination with Antiestrogens in HER2-Positive Breast Cancer Cells. Int. J. Mol. Sci, 25 (3165):1-21. 2024. FI: 4.9.
6. Vargas-Castro R, García-Becerra R, Díaz L, Avila E, Ordaz-Rosado D, Bernadez-Vallejo SV, Cano-Colín S, Camacho J, Larrea F, García-Quiroz J. Enhancing Tamoxifen Therapy with α-Mangostin: Synergistic Antiproliferative Effects on Breast Cancer Cells and Potential Reduced Endometrial Impact. Int. J. Mol. Sci, 16(1576):1-18. 2023. FI: 4.9
7. Morales-Guadarrama G, Méndez-Pérez EA, García-Quiroz J, Avila E, Ibarra-Sánchez MJ, Esparza-López J, García-Becerra R. Larrea, F.; Díaz, L. The Inhibition of the FGFR/PI3K/Akt Axis by AZD4547. Disrupts the Proangiogenic Microenvironment and Vasculogenic Mimicry Arising from the Interplay between Endothelial and Triple-Negative Breast Cancer Cells. Int. J. Mol. Sci, 24(13770): 1-24. 2023. FI: 4.9
8. Avila E, Noriega-Mejía BJ, González-Macías J, Cortes-Hernández U, García-Quiroz J, García-Becerra R, Díaz L. The Preventive Role of the Vitamin D Endocrine System in Cervical Cancer. Int. J. Mol. Sci, 24(8665):1-15. 2023. FI: 4.9
9. Díaz L, Bernadez-Vallejo SV, Vargas-Castro R, Avila E, Gómez-Ceja KA, García-Becerra R, Segovia-Mendoza M, Prado-Garcia H, Lara-Sotelo G, Camacho J, Larrea F, García-Quiroz J. The Phytochemical α-Mangostin Inhibits Cervical Cancer Cell Proliferation and Tumor Growth by Downregulating E6/E7-HPV Oncogenes and KCNH1 Gene Expression. Int. J. Mol. Sci, 24(3055):1-16. 2023. FI: 4.9
10. García-Quiroz J, Vázquez-Almazán B, García-Becerra R, Díaz L, Avila E. The Interaction of Human Papillomavirus Infection and Prostaglandin E Signaling in Carcinogenesis: A Focus on Cervical Cancer Therapeutics. Cells, 11(2528):1-32. 2022. FI: 5.1
11. Morales‐Guadarrama G, Méndez‐Pérez EA, García‐Quiroz J, Avila E, García‐Becerra R, Zentella‐Dehesa A, Larrea F, Díaz L. Endothelium‐Dependent Induction of Vasculogenic Mimicry in Human Triple‐Negative Breast Cancer Cells Is Inhibited by Calcitriol and Curcumin. Int. J. Mol. Sci, 23(7659): 1-14. 2022. FI: 4.29
12. Hernández-Rojas R, Jiménez-Arellano C, de la Fuente-Granada M, Ordaz-Rosado D, García-Becerra R, Valencia-Mayoral P, Álvarez-Arellano L, Eguía-Aguilar P, Velasco-Velázquez MA, González-Arenas A. The interplay between estrogen receptor beta and protein kinase C, a crucial collaboration for medulloblastoma cell proliferation and invasion. Cell Signal, 92:110246: 1-10. 2022. FI: 4.4
13. Santos-Martínez N, Díaz L, Ortiz-Ortega VM, Ordaz-Rosado D, Prado-Garcia H, Avila E, Larrea F, García-Becerra R. (corresponding author) Calcitriol induces estrogen receptor α expression through direct transcriptional regulation and epigenetic modifications in estrogen receptor-negative breast cancer cells. Am J Cancer Res, 11(12): 5951-5964. 2021. FI: 3.6
14. Segovia-Mendoza M, García-Quiroz J, Díaz L, García-Becerra R. (corresponding author) Combinations of Calcitriol with Anticancer Treatments for Breast Cancer: An Update. Int. J. Mol. Sci, 22(12741): 1-36. 2021. FI: 4.9.
15. García-Quiroz J, Cárdenas-Ochoa N, García-Becerra R, Morales-Guadarrama G, Méndez-Pérez EA, Santos-Cuevas C, Ramírez-Nava GJ, Segovia-Mendoza M, Prado-García H, Avila E, Larrea F, Díaz L. Antitumoral effects of dovitinib in triple-negative breast cancer are synergized by calcitriol in vivo and in vitro. J Steroid Biochem Mol Biol, 214(105979): 1-11. 2021. FI: 2.7
16. Morales-Guadarrama G, García-Becerra R, Méndez-Pérez EA, García-Quiroz J, Avila E, Díaz L. Vasculogenic mimicry in breast cancer: Clinical relevance and drivers. Cells 10(1758): 1-17. 2021. FI: 5.1
17. Hernández-Borja F, Mercado-Sánchez I, Alcaraz Y, García-Revilla MA, Villegas-Gómez C, Ordaz-Rosado D, Santos-Martínez N, García-Becerra R, Vazquez MA. Exploring novel capping framework: high substituent pyridine hydroxamic acid derivatives as potential antiproliferative agents. DARU J Pharm Sci 2: 291-310. 2021. FI: 2.5
18. Lara‐Sotelo G, Díaz L, García‐Becerra R, Avila E, Prado‐Garcia H, Morales‐Guadarrama G, Ibarra‐Sánchez MJ, Esparza‐López J, Larrea F, García‐Quiroz J. α‐Mangostin synergizes the antineoplastic effects of 5‐fluorouracil allowing a significant dose reduction in breast cancer cells. Processes, 9(458): 1-14. 2021. FI: 2.8
19. García-Olivares M, Romero-Córdoba S, Ortíz-Sánchez E, García-Becerra R, Segovia-Mendoza M, Rangel-Escareño C, Halhali A, Larrea F, Barrera D. Regulation of anti-tumorigenic pathways by the combinatory treatment of calcitriol and TGF-β in PC-3 and DU145 cells. J Steroid Biochem Mol Biol, 209(105831): 1-15. 2021. FI: 2.7
20. García S, Mercado-Sánchez I, Bahena L, Alcaraz Y, García-Revilla MA, Robles J, Santos-Martínez N, Ordaz-Rosado D, García-Becerra R, Vazquez MA. Design of fluorescent coumarin-hydroxamic acid derivatives as inhibitors of HDACs: Synthesis, anti-proliferative evaluation and docking studies. Molecules 25(5134): 1-27. 2020. FI: 4.2
21. Segovia-Mendoza M, Camacho-Camacho C, Rojas-Oviedo I, Prado-Garcia H, Barrera D, Martínez-Reza I, Larrea F, García-Becerra R. (corresponding author) An organotin indomethacin derivative inhibits cancer cell proliferation and synergizes the antiproliferative effects of lapatinib in breast cancer cells. Am J Cancer Res 10(10):3358-3369. 2020. FI: 3.6
22. Segovia-Mendoza M, Gómez de León CT, García-Becerra R, Ambrosio J, Nava-Castro KE, Morales-Montor J. The chemical environmental pollutants BPA and BPS induce alterations of the proteomic profile of different phenotypes of human breast cancer cells: a proposed interactome. Environ Res 191: 1-12. 2020. FI: 7.7