Contacto
Campos de conocimiento
Bioinformática
Biotecnología
Ciencias Genómicas
Genética y Fisiología Celular
Líneas de investigación
1. Genómica del cáncer: funcional y análisis bioinformáticos
2. Biología de la comunicación intracelular en cáncer: Vesículas extracelulares y biopsia líquida
3. Nuevas estrategias terapéuticas: reposicionamiento de fármacos y estudios preclínicos de la actividad anti-oncogénica de compuestos naturales (medicina complementaria)
Publicaciones
1. Calderon-DuPont D, Romero-Cordoba S, Tello JK, Espinosa A, Guerrero B, Contreras AV, et al. Impaired white adipose tissue fatty acid metabolism in mice fed a high-fat diet worsened by arsenic exposure, primarily affecting retroperitoneal adipose tissue. Toxicol Appl Pharmacol. 2023:116428. Epub 2023/02/22. doi: 10.1016/j.taap.2023.116428.
2. Flores-García LC, Ventura-Gallegos JL, Romero-Córdoba SL, Hernández-Juárez AJ, Naranjo-Meneses MA, et al. 2022. Sera from women with different metabolic and menopause states differentially regulate cell viability and Akt activation in a breast cancer in-vitro model. Sera from women with different metabolic and menopause states differentially regulate cell viability and Akt activation in a breast cancer in-vitro model. PLOS ONE 17(4): e0266073.
3. De Santis F, Romero-Cordoba SL, Castagnoli L, Volpari T, Faraci S, Fucà G, Tagliabue E, De Braud F, Pupa SM, Di Nicola M. BCL6 and the Notch pathway: a signaling axis leading to a novel druggable biotarget in triple negative breast cancer. Cell Oncol (Dordr). 2022 Mar 31. doi: 10.1007/s13402-022-00663-y. Epub ahead of print. PMID: 35357654.
4. Romero-Cordoba S.L.+*, Salido-Guadarrama I., Rebollar-Vega R., Bautista-Piña V., Dominguez-Reyes C., Tenorio-Torres A., Villegas-Carlos F., Fernández-López J.C., Uribe-Figueroa L., Alfaro-Ruiz L. and Hidalgo-Miranda A. Comprehensive omic characterization of breast cancer in Mexican-Hispanic women. Nature Communications 12(1):2245, 2021. +Equal contribution. * Corresponding.
5. Garcia-Olivares M., Romero-Cordoba S., Ortiz-Sanchez E., Garcia-Becerra R., Segovia-Mendoza M., Rangel-Escareno C., Halhali A., Larrea F. and Barrera D.. Regulation of anti-tumorigenic pathways by the combinatory treatment of calcitriol and TGF-beta in PC-3 and DU145 cells. J Steroid Biochem Mol Biol 209, 105831 (2021).
6. Romero-Cordoba S.L., Salido-Guadarrama I., Meneses M.E., Cosentino G., Iorio M.V., Tagliabue E., Torres N., Sanchez-Tapia M., Bonilla M., Castillo I., Petlacalco B., Tovar A.R. and Martinez-Carrera D. Mexican Ganoderma Lucidum Extracts Decrease Lipogenesis Modulating Transcriptional Metabolic Networks and Gut Microbiota in C57BL/6 Mice Fed with a High-Cholesterol Diet. Nutrients 13, (2020).
7. Cosentino G, Romero-Cordoba S, Plantamura I, Cataldo A, Iorio MV. miR-9-Mediated Inhibition of EFEMP1 Contributes to the Acquisition of Pro-Tumoral Properties in Normal Fibroblasts. Cells 9, (2020).
8. Cataldo A, Romero-Cordoba S, Plantamura I, Cosentino G, Hidalgo-Miranda A, Tagliabue E, Iorio MV: MiR-302b as a Combinatorial Therapeutic Approach to Improve Cisplatin Chemotherapy Efficacy in Human Triple-Negative Breast Cancer. 2020, Cancers (Basel), 12(8).
9. Cedro-Tanda A, Rios-Romero M, Romero-Cordoba S, Cisneros-Villanueva M, Rebollar-Vega RG, Alfaro-Ruiz LA, Jimenez-Morales S, Dominguez-Reyes C, Villegas-Carlos F, Tenorio-Torres A et al. A long non-coding RNA landscape in breast cancer reveals a potential role for linc-PPP1R1B in proliferation and apoptosis in HER2-enriched molecular subtype. Sci Rep 10, 13146. 2020
10. Navarrete-Bernal MGC, Cervantes-Badillo MG, Martínez-Herrera JF, Lara-Torres CO, Gerson-Cwilich R, Zentella-Dehesa A, Ibarra-Sánchez MdJ, Esparza-López J, Montesinos JJ, Cortés-Morales VA et al: Biological Landscape of Triple Negative Breast Cancers Expressing CTLA-4. et al. Sandra Romero-Córdoba*, Leticia Rocha-Zavaleta. Biological Landscape of Triple Negative Breast Cancers Expressing CTLA-4. Frontiers in Oncology 2020, 10(1206), * Co-corresponding author. 2020.
11. Pedroza-Torres A*, Romero-Córdoba SL*, Justo-Garrido M, Salido-Guadarrama I, Rodríguez-Bautista R, Montaño S, Muñiz-Mendoza R, Arriaga-Canon C, Fragoso-Ontiveros V, Álvarez-Gómez RM, Hernández G and Herrera LA. MicroRNAs in Tumor Cell Metabolism: Roles and Therapeutic Opportunities. Front. Oncol. 9:1404. 2019. *Equal contribution
12. Pietrantonio F, Yaeger R, Schrock AB, Randon G, Romero-Cordoba S, Rossini D, Fucà G, Ross JS, Kotani D, Madison R et al: Atypical RAS Mutations in Metastatic Colorectal Cancer. JCO Precision Oncology (3):1-11. 2019.
13. Romero-Cordoba S, Meneghini E, Sant M, Iorio MV, Sfondrini L, Paolini B, Agresti R, Tagliabue E, Bianchi F: Decoding Immune Heterogeneity of Triple Negative Breast Cancer and Its Association with Systemic Inflammation. Cancers (Basel), 11(7). 2019.
14. Beltran-Anaya FO, Romero-Cordoba S, Rebollar-Vega R, Arrieta O, Bautista-Pina V, Dominguez-Reyes C, et al. Expression of long non-coding RNA ENSG00000226738 (LncKLHDC7B) is enriched in the immunomodulatory triple-negative breast cancer subtype and its alteration promotes cell migration, invasion, and resistance to cell death. Mol Oncol. doi: 10.1002/1878-0261.12446. PubMed PMID: 30648789. 2019.
15. Borgonio-Cuadra VM*, Valdez-Vargas C*, Romero-Cordoba S, Hidalgo-Miranda A, Tapia-Guerrero Y, Cerecedo-Zapata CM, et al. Wide Profiling of Circulating MicroRNAs in Spinocerebellar Ataxia Type 7. Mol Neurobiol. 2019.
16. Castagnoli L*, Cancila V*, Romero-Cordoba SL, Faraci S, Talarico G, Belmonte B, et al. WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer. Oncogene. 2019.
17. Fernandez-Lopez JC, Romero-Cordoba S, Rebollar-Vega R, Alfaro-Ruiz LA, Jimenez-Morales S, Beltran-Anaya F, et al. Population and breast cancer patients' analysis reveals the diversity of genomic variation of the BRCA genes in the Mexican population. Hum Genomics. 13(1):3. 2019.
18. Romero-Cordoba SL, Rodriguez-Cuevas S, Bautista-Pina V, Maffuz-Aziz A, D'Ippolito E, Cosentino G, et al. Loss of function of miR-342-3p results in MCT1 over-expression and contributes to oncogenic metabolic reprogramming in triple negative breast cancer. Sci Rep.;8(1):12252. 2018.
19. Cortes-Malagon EM, Palacios-Reyes C, Romero-Cordoba S, Mendoza-Villanueva D, Escobar-Herrera J, Verdejo-Torres O, Contreras RG, Fernadez-Tilapa G, Moreno-Eutimio MA, Moreno J et al: The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo. Biomed Res Int 7868645. 2017.
20. Arellano-Llamas R, Alfaro-Ruiz L, Arriaga Canon C, Imaz Rosshandler I, Cruz-Lagunas A, Zuniga J, Rebollar Vega R, Wong CW, Maurer-Stroh S, Romero Cordoba S, et al. Molecular features of influenza A (H1N1)pdm09 prevalent in Mexico during winter seasons 2012-2014. PLoS One. 2017.
21. Bianchi F, Sommariva M, De Cecco L, Triulzi T, Romero-Cordoba S, Tagliabue E, Sfondrini L, Balsari A. Expression and prognostic significance of the autoimmune regulator gene in breast cancer cells. Cell Cycle. 5(23):3220-3229. 2016.
22. Beltran-Anaya FO, Cedro-Tanda A, Hidalgo-Miranda A*, Romero-Cordoba SL*: Insights into the Regulatory Role of Non-coding RNAs in Cancer Metabolism. Front Physiol, 7:342. 2016. *Co-corresponding author
23. Baroni S, Romero-Cordoba S, Plantamura I, Dugo M, D'Ippolito E, Cataldo A, Cosentino G, Angeloni V, Rossini A, Daidone MG et al: Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts. Cell Death Dis, 7(7): e2312. 2016.
24. Zacapala-Gomez AE, Del Moral-Hernandez O, Villegas-Sepulveda N, Hidalgo-Miranda A, Romero-Cordoba SL, Beltran-Anaya FO, Leyva-Vazquez MA, Alarcon-Romero Ldel C, Illades-Aguiar B: Changes in global gene expression profiles induced by HPV 16 E6 oncoprotein variants in cervical carcinoma C33-A cells. Virology, 488:187-195. 2016
25. Ramiro José González-Duarte, Verna Cázares-Ordoñez, Sandra Romero-Córdoba, Lorenza Díaz, Víctor Ortíz, Julio Augusto Freyre-González, Alfredo Hidalgo-Miranda, Fernando Larrea, Euclides Avila. Calcitriol increases Dicer expression and modifies the microRNAs signature in SiHa cervical cancer cells. Biochemistry and Cell Biology. 2015.
26. Romero-Cordoba SL, Salido-Guadarrama I, Rodriguez-Dorantes M, Hidalgo-Miranda A: miRNA biogenesis: biological impact in the development of cancer. Cancer Biol Ther, 15(11):1444-1455. 2014.
27. Salido-Guadarrama I, Romero-Cordoba S, Peralta-Zaragoza O, Hidalgo-Miranda A, Rodriguez-Dorantes M: MicroRNAs transported by exosomes in body fluids as mediators of intercellular communication in cancer. Onco Targets Ther, 7:1327-1338. 2014.
28. Borgonio Cuadra VM, Gonzalez-Huerta NC, Romero-Cordoba S, Hidalgo-Miranda A, Miranda-Duarte A: Altered expression of circulating microRNA in plasma of patients with primary osteoarthritis and in silico analysis of their pathways. PLoS One, 9(6):e97690. 2014.
29. Martinez-Pacheco M, Hidalgo-Miranda A, Romero-Cordoba S, Valverde M, Rojas E: MRNA and miRNA expression patterns associated to pathways linked to metal mixture health effects. Gene, 533(2):508-514. 2014.
30. Ojesina AI, Lichtenstein L, Freeman SS, Pedamallu CS, Imaz-Rosshandler I, Pugh TJ, Cherniack AD, Ambrogio L, Cibulskis K, Bertelsen B. Romero-Cordoba S et al: Landscape of genomic alterations in cervical carcinomas. Nature, 506(7488):371-375. 2014.
31. Cortes-Malagon EM, Bonilla-Delgado J, Diaz-Chavez J, Hidalgo-Miranda A, Romero-Cordoba S, Uren A, Celik H, McCormick M, Munguia-Moreno JA, Ibarra-Sierra E et al: Gene expression profile regulated by the HPV16 E7 oncoprotein and estradiol in cervical tissue. Virology, 447(1-2):155-165. 2013.
32. Ramirez-Martinez G, Cruz-Lagunas A, Jimenez-Alvarez L, Espinosa E, Ortiz-Quintero B, Santos-Mendoza T, Herrera MT, Canche-Pool E, Mendoza C, Banales JL, Romero-Cordoba S et al: Seasonal and pandemic influenza H1N1 viruses induce differential expression of SOCS-1 and RIG-I genes and cytokine/chemokine production in macrophages. Cytokine, 62(1):151-159. 2013
33. Banerji S, Cibulskis K, Rangel-Escareno C, Brown KK, Carter SL, Frederick AM, Lawrence MS, Sivachenko AY, Sougnez C, Zou L, Romero-Cordoba SL et al: Sequence analysis of mutations and translocations across breast cancer subtypes. Nature, 486(7403):405-409. 2012.
34. Romero-Cordoba S, Rodriguez-Cuevas S, Rebollar-Vega R, Quintanar-Jurado V, Maffuz-Aziz A, Jimenez-Sanchez G, Bautista-Pina V, Arellano-Llamas R, Hidalgo-Miranda A: Identification and pathway analysis of microRNAs with no previous involvement in breast cancer. PLoS One, 7(3):e31904. 2012.
