Contacto
Campos de conocimiento
Bioquímica
Neurobiología
Líneas de investigación
- Triptófano y kinureninas como biomarcadores pronósticos y tempranos de deterioro cognitivo y depresión.
- Impacto de los metabolitos de la vía de la kinurenina en las alteraciones conductuales causadas por la intoxicación con metales pesados.
- Antígenos de Toxoplasma gondii y su efecto en alteraciones cognitivas y motoras
- Caracterización redox del catabolismo del triptofano.
Publicaciones
Blanco Ayala T, Lugo Huitrón R, Carmona Aparicio L, Ramírez Ortega D, González Esquivel D, Pedraza Chaverrí J, Pérez de la Cruz G, Ríos C, Schwarcz R, Pérez de la Cruz V. 2015. Alternative kynurenic acid synthesis routes studied in the rat cerebellum. Front Cell Neurosci 18; 9:178. Citas: 12
Reyes-Ocampo J, Ramírez-Ortega D, Vázquez Cervantes GI, Pineda B, Montes de Oca Balderas P, González-Esquivel D, Sánchez-Chapul L, Lugo-Huitrón R, Silva-Adaya D, Ríos C, Jiménez-Anguiano A, Pérez-de la Cruz V. 2015. Mitochondrial dysfunction related to cell damage induced by 3-hydroxykynurenine and 3-hydroxyanthranilic acid: Non-dependent-effect of early reactive oxygen species production. Neurotoxicology. 50:81-91. Citas: 13
Orozco-Morales M, Sánchez-García FJ, Golán-Cancela I, Hernández-Pedro N, Costoya JA, Pérez de la Cruz V, Moreno-Jiménez S, Sotelo J, Pineda B. 2015. RB mutation and RAS overexpression induce resistance to NK cell-mediated cytotoxicity in glioma cells. Cancer Cell Int.15:57. Citas: 6
Hernández-Pedro N, Magana-Maldonado R, Ramiro AS, Pérez-De la Cruz V, Rangel-López E, Sotelo J, Pineda B. 2016. PAMP-DAMPs interactions mediates development and progression of multiple sclerosis. Front Biosci (Schol Ed). 8:13-28. Citas: 6
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, et al. 2016. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. Citas: 2034
González Esquivel D, Ramírez-Ortega D, Pineda B, Castro N, Ríos C, Pérez de la Cruz V. 2016. Kynurenine pathway metabolites and enzymes involved in redox reactions. Neuropharmacology. S0028-3908(16)30085-5. doi: 10.1016/j.neuropharm.2016.03.013. Citas: 25
Salazar-Ramiro A, Ramírez-Ortega D, Pérez de la Cruz V, Hérnandez-Pedro NY, González-Esquivel DF, Sotelo J, Pineda B. 2016. Role of Redox Status in Development of Glioblastoma. Front Immunol. 7:156. Citas: 26
Ramírez-Ortega D, Salazar-Ramiro A, González-Esquivel D, Ríos C, Pineda B, and Pérez de la Cruz V. 2017. 3-hydroxykynurenine and 3-hydroxyanthranilic acid enhance the toxicity induced by copper in rat astrocytes culture. Oxidative Medicine and Cellular Longevity. Citas: 3
Romano-Feinholz S, Salazar-Ramiro A, Muñoz-Sandoval E, Magaña-Maldonado R, Hernández Pedro N, Rangel López E, González Aguilar A, Sánchez García A, Sotelo J, Pérez de la Cruz V, Pineda B. 2017. Cytotoxicity induced by carbon nanotubes in experimental malignant glioma. Int J Nanomedicine. 21;12:6005-6026. doi: 10.2147/IJN.S139004. Citas: 3
Ramos-Chávez LA, Lugo Huitrón R, González Esquivel D, Pineda B, Ríos C, Silva-Adaya D, Sánchez-Chapul L, Roldán-Roldán G, Pérez de la Cruz V. 2018. Relevance of Alternative Routes of Kynurenic Acid Production in the Brain. Oxidative Medicine and Cellular Longevity, 1-14. Citas: 3
Cabrera-Aldana E, Moreno-Jímenez S, Magaña-Maldonado R, Hernández-Pedro N, Salazar A, Pérez de la Cruz V, Moreno-Martínez M, Pérez de la Cruz G, Ortega-Porcayo A, Márquez Navarro A, Alonso-Vanegas M, Sotelo J, Pineda B. 2018. Glioblastoma Topography and Stem-Cell Markers Related with Survival. Journal of Oncology Research and Therapy.
Cortés-Morales YY, Vanoye-Carlo A, Castillo-Rodríguez RA, Serrano-Posada H, González-Valdez A, Ortega-Cuellar D, Hernández-Ochoa B, Moreno-Vargas LM, Prada-Gracia D, Sierra-Palacios E, Pérez de la Cruz V, Marcial-Quino J, Gómez-Manzo S. 2018. Cloning and biochemical characterization of three glucose‑6‑phosphate dehydrogenase mutants presents in the Mexican population. Int J Biol Macromol. 119:926-936.
Morales-Luna L, Serrano-Posada H, González-Valdez A, Ortega-Cuellar D, Vanoye-Carlo A, Hernández-Ochoa B, Sierra-Palacios E, Rufino-González Y, Castillo-Rodríguez RA, Pérez de la Cruz V, Moreno-Vargas L, Prada-Gracia D, Marcial-Quino J, Gómez-Manzo S. 2018. Biochemical Characterization and Structural Modeling of Fused Glucose-6-Phosphate Dehydrogenase-Phosphogluconolactonase from Giardia lamblia. Int J Mol Sci.19(9).
Ramos Chavez L, Roldán-Roldán G, Garcia Juarez B, González-Esquivel D, Pérez de la Cruz G, Pineda B, Ramirez-Ortega D, Garcia Muñoz I, Jimenez Herrera B, Ríos C, Gomez Manzo S, Marcial Quino J, Sánchez Chapul L, Carrillo-Mora P, Pérez de la Cruz V. 2018. Low tryptophan serum levels as a biomarker of global cognition performance in non-demented elderly women. Oxidative Medicine and Cellular Longevity. Citas :3
Pineda B, Sánchez García FJ, Olascoaga NK, Pérez de la Cruz V, Salazar A, Moreno-Jiménez S, Hernández Pedro N, Márquez-Navarro A, Ortiz Plata A, Sotelo J. 2019. Malignant Glioma Therapy by Vaccination with Irradiated C6 Cell-Derived Microvesicles Promotes an Antitumoral Immune Response. Mol Ther. pii: S1525-0016(19)30250-3. doi: 10.1016/j.ymthe.2019.05.016
Chavez-Cortez E, Vargas Felix G, Rangel López E, Sotelo J, Martínez-Canseco C, Pérez-de la Cruz V, Pineda B. 2019. Production and Evaluation of an Avian IgY Immunotoxin against CD133+ for Treatment of Carcinogenic Stem Cells in Malignant Glioma: IgY Immunotoxin for the Treatment of Glioblastoma. Journal of Oncology 2019.
Ramirez Nava E, Ortega Cuellar D, Gonzalez Valdez A, Castillo Rodriguez A, Yaxal Ponce G, Hernandez Ochoa B, Cardenas Rodriguez N, Martinez Rosas V, Morales Luna L, Serrano Posada H, Sierra Palacios E, Arreguin Espinosa R, Cuevas Cruz M, Rocha Ramirez L, Pérez de la Cruz V, Marcial Quino J, Gómez Mnazo S. 2019. Molecular cloning and exploration of the biochemical and functional analysis of recombinant Glucose-6-phosphate dehydrogenase from Gluconoacetobacter diazotrophicus PAL5. Molecular Biophysics, en prensa.
