Contacto
Líneas de investigación
Cisticercosis humana y porcina (Taenia solium)
Genómica de parásitos helmintos.
Transfección funcional de genes heterólogos en Taenia crassiceps
Proteómica de Parásitos helmintos.
Nuevos antígenos para inmunodiagnóstico de la cisticercosis.
Proteínas involucradas en la relación huésped-parásito en la cisticercosis por Taenia solium.
Publicaciones
Dolores A. Ayón-Núñez, Gladis Fragoso, Clara Espitia, Martín García-Varela, Xavier Soberón, Gabriela Rosas, Juan P. Laclette and Raúl J. Bobes. Identification and characterization of Taenia solium enolase as a plasminogen-binding protein. Acta Trop. 2018. 182:69-79. F.I. 2.218
Núñez G, Villalobos N, Herrera P, Hernández M, Navarrete J, Martínez A, Martínez M, Bobes RJ, Fragoso G, Sciutto E, and Del Arenal P. Anti GK1 antibodies damage Taenia crassiceps cysticerci through complement activation. Journal of Parasitology. 2018. 117(8):2543-2553. F.I. 1.326
Ayón-Núñez DA, Fragoso G, Bobes RJ, Laclette JP. Plasminogen-binding proteins as an evasion mechanism of the host's innate immunity in infectious diseases. Biosci Rep. 2018. 38(5). pii: BSR20180705. F.I. 2.939
Díaz-Godínez C, González-Galindo X, Meza-Menchaca T, Bobes RJ, de la Garza M, León-Sicairos N, Laclette JP, Carrero JC. Synthetic bovine lactoferrin peptide Lfampin kills Entamoeba histolytica trophozoites by necrosis and resolves amoebic intracecal infection in mice. Biosci Rep. 2019. 39(1). pii: BSR20180850. F.I. 2.939
Juan Voutssas-Lara, Jacquelynne Cervantes-Torres, Marisela Hernández, Raúl J. Bobes, Edmundo Lamoyi, Ricardo A. Vázquez-Ramírez, Luis Mendoza, Karen L. Reyes-Barrera*, Rogelio López-Martínez, Sergio Rosales-Mendoza‡, Leonor Huerta, Gladys Fragoso, Edda Sciutto. Influence of Adjuvants on the Amount, Specificity and Functional Activity of Antibody Response to Human Influenza Vaccine in Mice. Mol Immunol. 2021. 135:398-407. F.I. 4.407
MJ Contreras-Luna; G Fragoso-Gonzalez; René A Segura-Velazquez; J Cervantes-Torres; R Alonso-Morales; Luis A Ramírez-Martínez, Dolores A Ayón-Núñez, Raúl J Bobes, Ivan Sanchez-Betancourt. Antibody responses to recombinant nsp1 and nsp11 of Porcine reproductive and respiratory syndrome virus and evaluation of their neutralizing activity. Vet Med Sci. 2022. 8(2):610-618. F.I. 1.950
Guerrero-Hernández J, Bobes RJ, García-Varela M, Castellanos-Gonzalez A, Laclette JP. Identification and functional characterization of the siRNA pathway in Taenia crassiceps by silencing Enolase A. Acta Trop. 2022. 225:106197. F.I. 3.112
Cárdenas G, Chávez-Canales M, Espinosa AM, Jordán-Ríos A, Malagon DA, Murillo MFM, Araujo LVT, Campos RLB, Wong-Chew RM, González LER, Cresencio KI, Velázquez EG, de la Cerda MR, Leyva Y, Hernández-Ruiz J, Hernández-Medel ML, León-Hernández M, Quero KM, Monciváis AS, Díaz SH, Martínez IRZ, Martínez-Cuazitl A, Salazar INM, Sarmiento EB, Peña AF, Hernández PS, Reynoso RIA, Reyes DM, Del Río Ambriz LR, Bonilla RAA, Cruz J, Huerta L, Fierro NA, Hernández M, Pérez-Tapia M, Meneses G, Espíndola-Arriaga E, Rosas G, Chinney A, Mendoza SR, Hernández-Aceves JA, Cervantes-Torres J, Rodríguez AF, Alor RO, Francisco SO, Salazar EA, Besedovsky H, Romano MC, Bobes RJ, Jung H, Soldevila G, López-Alvarenga J, Fragoso G, Laclette JP, Sciutto E. Intranasal dexamethasone: a new clinical trial for the control of inflammation and neuroinflammation in COVID-19 patients. Trials. 2022 Feb 14;23(1):148. F.I. 2.606
Carrero JC, Curay-Herrera V, Chacón-Niño L, Krengel F, Guzmán-Gutiérrez SL, Silva-Miranda M, González-Ramírez LC, Bobes-Ruíz R, Espitia CI, Reyes-Chilpa R, Laclette JP. Potent anti-amoebic effects of Ibogaine, Voacangine and the root bark alkaloid fraction of Tabernaemontana arborea. Planta Med. 2022. 25. F.I. 3.35
Bobes R.J., Estrada K., Rios-Valencia D., Calderón-Gallegos A., de la Torre P., Carrero J.C., Sanchez-Flores A. and Laclette J.P. The genomes of two strains of Taenia crassiceps the animal model for the study of human cysticercosis. Frontiers in Cellular and Infection Microbiology, Parasite and Host. 2022. En prensa. F.I. 4.30
Dolores Adriana Ayón-Núñez, Jacquelynne Cervantes-Torres, Carlos Cabello-Gutiérrez, Sergio Rosales-Mendoza, Diana Rios-Valencia, Leonor, Huerta, Raúl J. Bobes, Julio César Carrero, René Segura-Velázquez, Nora Alma Fierro, Marisela Hernández, Joaquín Zúñiga-Ramos, Gerardo Gamba, Graciela Cárdenas, Emanuel Frías-Jiménez, Luis Alonso Herrera, Gladis Fragoso, Edda Sciutto, Francisco Suárez-Güemes, Juan Pedro Laclette. An RBD-based diagnostic method useful for the surveillance of protective immunity against SARS‐CoV‐2 in the population. Diagnostics. 2022. En prensa. F.I. 3.70