Principios organizacionales, dinámicos y evolutivos gobernando la biología de sistemas de diversas redes biológicas complejas
Análisis big-data de redes biológicas complejas empleando datos experimentales a gran escala
Predicción masiva de redes de regulación
Biología comparativa y funcional de sistemas

Publicaciones

Taboada-Castro, H., Hernández-Álvarez, A.J., Escorcia-Rodríguez, J.M., Freyre-Gonzalez, J.A., Galán-Vásquez, E., Encarnacion-Guevara, S. Rhizobium etli CFN42 and Sinorhizobium meliloti 1021 bioinformatic transcriptional regulatory networks from culture and symbiosis. Frontiers in Bioinformatics 4:1419274 (2024) Factor de Impacto: 2.800

Escorcia-Rodríguez, J.M., Gaytan-Nuñez, E., Hernandez-Benitez, E.M., Zorro-Aranda, A., Tello-Palencia, M.A., Freyre-Gonzalez, J.A.* Improving gene regulatory network inference and assessment: The importance of using network structure. Frontiers in Genetics 14:1143382 (2023) Artículo sometido por invitación a la edición especial sobre “Insights in Synthetic Biology 2022 / 2023: Novel Developments, Current Challenges, and Future Perspectives”. Factor de impacto: 4.772

Taboada-Castro, H., Gil, J., Gómez-Caudillo, L., Escorcia-Rodríguez, J.M., Freyre-Gonzalez, J.A., Encarnacion-Guevara, S. R. etli CFN42 proteomes showed isoenzymes in free-living and symbiosis with a different transcriptional regulation inferred from a transcriptional regulatory network. Frontiers in Microbiology 13:947678 (2022) Factor de impacto: 6.064

Escorcia-Rodríguez, J.M., Esposito, M., Freyre-Gonzalez, J.A., Moreno-Hagelsieb, G. Non-synonymous to synonymous substitutions suggest that orthologs tend to keep their functions, while paralogs are a source of functional novelty. PeerJ 10:e13843 (2022) Factor de impacto: 3.061

Freyre-Gonzalez, J.A.*, Escorcia-Rodríguez, J.M., Gutiérrez-Mondragón, L.F., Martí-Vértiz, J. Torres-Franco C.N., Zorro-Aranda, A. System principles governing the organization, architecture, dynamics, and evolution of gene regulatory networks. Frontiers in Bioengineering and Biotechnology 10:888732 (2022) Artículo sometido por invitación a la edición especial sobre “Insights in Synthetic Biology 2021: Novel Developments, Current Challenges, and Future Perspectives”. Factor de impacto: 5.890

Zorro-Aranda, A., Escorcia-Rodríguez, J.M., González-Kise, J.K., Freyre-González, J.A.* Curation, inference, and assessment of a globally reconstructed gene regulatory network for Streptomyces coelicolor. Scientific Reports 12(1):2840 (2022) Factor de impacto: 4.380

Escorcia-Rodríguez, J.M., Tauch, A., Freyre-González, J.A.* Corynebacterium glutamicum regulation beyond transcription: Organizing principles and reconstruction of an extended regulatory network incorporating regulations mediated by small RNA and protein-protein interactions. Microorganisms 9(7):1395 (2021) Artículo sometido por invitación a la edición especial sobre “Genetics and Physiology of Corynebacteria”. Factor de impacto: 4.152

Camacho-Hernández, D.A., Nieto-Caballero, V.E., León-Burguete, J.E., Freyre-González, J.A.* Partition Quantitative Assessment (PQA): A quantitative methodology to assess the embedded noise in clustered omics and systems biology data. Applied Sciences 11(13):5999 (2021) Artículo sometido a la edición especial “Towards a Systems Biology Approach”. Factor de impacto: 2.474

Escorcia-Rodríguez, J.M., Tauch, A., Freyre-González, J.A.* Abasy Atlas v2.2: The most comprehensive and up-to-date inventory of meta-curated, historical, bacterial regulatory networks, their completeness and system-level characterization. Computational and Structural Biotechnology Journal 18:1228-1237 (2020) Artículo sometido por invitación a la edición especial sobre “Functional Genomics and Systems Biology”. Factor de impacto: 6.018

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx