1- Neurocisticercosis (NCC) humana
- Factores involucrados en la heterogeneidad de la NCC, y en la resistencia a los tratamientos.
- Inflamación y NCC
- Epidemiología

2- Neuroinflamación y epilepsia
- Marcadores periféricos de neuroinflamación asociados a la epilepsia del lóbulo temporal

3- Impacto del COVID sobre las patologías neurológicas

Publicaciones

69- Marcin Sierra M, Arroyo M, Cadena Torres M, Ramírez Cruz N, García Hernández F, Taboada D, Galicia Martínez Á, Govezensky T, Sciutto E, Toledo A, Fleury A (corresponding author). Extraparenchymal neurocysticercosis: Demographic, clinicoradiological, and inflammatory features. PLoS Negl Trop Dis. 11(6):e0005646. 2017 Jun 9; FI : 4.45
70- Meneses G, Gevorkian G, Florentino A, Bautista MA, Espinosa A, Acero G, Díaz G, Fleury A, Pérez Osorio IN, Del Rey A, Fragoso G, Sciutto E, Besedovsky H. Intranasal delivery of dexamethasone efficiently controls LPS-induced murine neuroinflammation. Clin Exp Immunol. 190(3):304-314. 2017 Dec. FI: 3.41
71- Adalid-Peralta L, Rosas G, Arce-Sillas A, Bobes RJ, Cárdenas G, Hernández M, Trejo C, Meneses G, Hernández B, Estrada K, Fleury A, Laclette JP, Larralde C, Sciutto E, Fragoso G. Effect of Transforming Growth Factor-β upon Taenia solium and Taenia crassiceps Cysticerci. Sci Rep. 7(1):12345. 2017 Sep 27. FI: 4.259
72- Carpio A, Fleury A, Romo ML, Abraham R. Neurocysticercosis: the good, the bad, and the missing. Expert Rev Neurother. 18(4):289-301. 2018 Apr. FI: 3.692
73- Fleury A, Alaez C, Dessein A, Rosetti M, Saenz B, Hernández M, Bobes RJ, Ramírez-Aquino R, Sciutto E, Gorodezky C, Fragoso G. No association of IL2, IL4, IL6, TNF, and IFNG gene polymorphisms was found with Taenia solium human infection or neurocysticercosis severity in a family-based study. Hum Immunol. 79(7):578-582. 2018 Jul. FI: 1.994
74- Morales J, Martínez JJ, Villalobos N, Hernández M, Ramírez R, Salgado-Estrada B, Jiménez H, Figueroa A, Sánchez LM, Lazcano E, Fleury A, Aluja A, Sciutto E. Persistent Taenia solium Cysticercosis In the State of Morelos, Mexico: Human and Porcine Seroprevalence. J Parasitol. 104(5):465-472. 2018 Oct. FI: 1.395.
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75- Arce-Sillas A, Cárdenas G, Álvarez-Luquín D, Hernandez M, Del Rey A, Besedovsky H, Gómez-Fuentes S, Fragoso G, Fleury A, Sciutto E, Adalid-Peralta L. Treatment-Resistant Human Extraparenchymal Neurocysticercosis: An Immune-Inflammatory Approach to Cysticidal Treatment Outcome. Neuroimmunomodulation. 25(2):103-109. 2018. FI: 2.238
76- Meneses G, Rosetti M, Espinosa A, Florentino A, Bautista M, Díaz G, Olvera G, Bárcena B, Fleury A, Adalid-Peralta L, Lamoyi E, Fragoso G, Sciutto E. Recovery from an acute systemic and central LPS-inflammation challenge is affected by mouse sex and genetic background. PLoS One. 13(8):e0201375. 2018 Aug 22. FI: 2.766.
77- Carpio A, Fleury A, Kelvin EA, Romo ML, Abraham R, Tellez-Zenteno J. New guidelines for the diagnosis and treatment of neurocysticercosis: a difficult proposal for patients in endemic countries. Expert Rev Neurother. 18(10):743-747. 2018 Oct. FI: 3.692
78- Toledo A, Osorio R, Matus C, Martinez Lopez Y, Ramirez Cruz N, Sciutto E, Fragoso G, Arauz A, Carrillo-Mezo RA, Fleury A (corresponding author). Human extraparenchymal neurocysticercosis: The control of inflammation favors the host…but also the parasite. Front Immunol. 16;9:2652. 2018 Nov FI: 5.511. DOI: 10.3389/fimmu.2018.02652.
79- Delgado-García G, Méndez-Zurita VA, Bayliss L, Flores-Rivera J, Fleury A (corresponding author). Neurocysticercosis: mimics and chameleons. Pract Neurol. 19(2):88-95. 2019 Abr. FI: 0.93. doi: 10.1136/practneurol-2017-001788.
80- Garfias S, Tamaya Domínguez B, Toledo Rojas A, Arroyo M, Rodríguez U, Boll C, Sosa AL, Sciutto E, Adalid-Peralta L, Martínez López Y, Fragoso G, Fleury A (corresponding author). Peripheral lymphocyte phenotypes in Alzheimer and Parkinson Diseases. Neurología. pii: S0213-4853(19)30013-1. 2019 Mar 11. FI: 1.938 . doi: 10.1016/j.nrl.2018.10.004.
81- Osorio R, Carrillo-Mezo R, Romo ML, Toledo A, Matus C, González-Hernández I, Jung H, Fleury A (corresponding author). Factors associated with cysticidal treatment response in extraparenchymal neurocysticercosis. J Clin Pharmacol. 59(4):548-556. 2019 Apr. FI: 2.881. doi: 10.1002/jcph.1346.
82- Meneses G, Cárdenas G, Espinosa A, Rassy D, Perez-Osorio IN, Bárcena B, Fleury A, Besedovsky H, Fragoso G, Sciutto E. Sepsis: Developing new alternatives to reduce neuroinflammation and attenuate brain injury. Ann New York Acad Sci. 1437(1):43-56. 2019 Feb. FI: 4.277 doi: 10.1111/nyas.13985.
83- Hamamoto Filho PT, Zanini MA, Fleury A. Hydrocephalus in Neurocysticercosis: Challenges for Clinical Practice and Basic Research Perspectives. World Neurosurg. 126:264-271. 2019 Jun. FI: 1.723. doi: 10.1016/j.wneu.2019.03.071.
84- Herrera Vazquez O, Romo ML, Fleury A (corresponding author). Neurocysticercosis and HIV Infection: what can we learn from the published literature? Arq Neuropsiquiatr.;77(5):357-365. 2019 May 1. FI: 0.843. doi: 10.1590/0004-282X20190054.
85- Hernández M, Astudillo OG, Diego G, de-la-Rosa-Arana JL, Meza-Lucas A, García-Rodea R, Romo ML, Toledo A, Parkhouse RM, Garate T, Sciutto E, Fleury A
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(corresponding author). Immunodiagnosis of human neurocysticercosis: comparative performance of serum diagnostic tests in Mexico. Parasitol Res. 118(10):2891-2899. 2019 Oct. FI: 2.067. doi: 10.1007/s00436-019-06425-4
86- Villegas M, Sciutto E, Rosetti M, Fleury A, Fragoso G. Association of TRAF1/C5 locus polymorphisms with epilepsy and clinical traits in Mexican neurocysticercosis patients. Infect Immun. pii: IAI.00347-19. 2019 Sep 30. FI : 3.256. doi: 10.1128/IAI.00347-19.
87- Palomares-Alonso F, Toledo A, Palencia Hernández G, Jung-Cook H, Fleury A (corresponding author). Effect of dexamethasone on albendazole cysticidal activity in experimental cysticercosis by Taenia crassiceps in BALB/c mice: In vitro and in vivo evaluation. Exp Parasitol. 208:107801. 2020 Jan. FI: 1.719. doi: 10.1016/j.exppara.2019.107801.
88- González-Mundo I, Pérez-Vielma NM, Gómez-López M, Fleury A, Correa-Basurto J, Rosales-Hernández MC, Sixto-López Y, Martínez-Godinez MLÁ, Domínguez-López A, Miliar-García A. DNA methylation of the RE-1 silencing transcription factor in peripheral blood mononuclear cells and gene expression of antioxidant enzyme in patients with late-onset Alzheimer disease. Exp Gerontol. 2020 Jul 15;136:110951. FI: 3.376. doi: 10.1016/j.exger.2020.110951.
89- Romo ML, Hernández M, Astudillo OG, Diego G, de-la-Rosa-Arana JL, Meza-Lucas A, García-Rodea R, Toledo A, Parkhouse RME, Garate T, Sciutto E, Fleury A (corresponding author). Diagnostic value of glycoprotein band patterns of three serologic enzyme-linked immunoelectrotransfer blot assays for neurocysticercosis. Parasitol Res. 2020 Aug;119(8):2521-2529. FI: 2.067. doi: 10.1007/s00436-020-06750-z.
90- Espinosa A, Meneses G, Chavarría A, Mancilla R, Pedraza-Chaverri J, Fleury A, Bárcena B, Pérez-Osorio IN, Besedovsky H, Arauz A, Fragoso G, Sciutto E. Intranasal Dexamethasone Reduces Mortality and Brain Damage in a Mouse Experimental Ischemic Stroke Model. Neurotherapeutics. 2020 Jul 6. FI: 5.719. doi: 10.1007/s13311-020-00884-9.
91- Hamamoto Filho PT, Singh G, Winkler AS, Carpio A, Fleury A (corresponding author). Could Differences in Infection Pressure Be Involved in Cysticercosis Heterogeneity? Trends Parasitol. 2020 Oct;36(10):826-834. FI: 6.918. doi: 10.1016/j.pt.2020.07.003.
92- Parkhouse RME, Sciutto E, Hernández M, Cortez MM, Carpio A, Fleury A. Extraparenchymal human neurocysticercosis induces autoantibodies against brain tubulin and MOG35-55 in cerebral spinal fluid. J Neuroimmunol. 2020 Sep 12;349:577389. FI: 3.033. doi: 10.1016/j.jneuroim.2020.577389.
93- Parkhouse RME, Sciutto E, Cortez MM, Fleury A, Carpio A. Neurocysticercosis: Autoantibodies, another cog in the wheel of its variable pathogenicity. J Exp Neurol. 2020; 1(3): 103-108. FI: sin. Doi: https://doi.org/10.33696/Neurol.1.017
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94- Cuellar-Hernandez JJ, Valadez-Rodriguez A, Olivas-Campos R, Tabera-Tarello P, Juan-Orta DS, Segura-López R, Fleury A. Intrasellar cysticercosis cyst treated with a transciliary supraorbital keyhole approach - A case report. Surg Neurol Int. 2020 Dec 11;11:436. doi: 10.25259/SNI_755_2020. FI: 1.12
95- Mendlovic F, Fleury A, Flisser A. Zoonotic Taenia infections with focus on cysticercosis due to Taenia solium in swine and humans. Res Vet Sci. 2021 Jan;134:69-77. doi: 10.1016/j.rvsc.2020.11.015. FI: 2.359 .
96- Cárdenas G, Torres-García D, Cervantes-Torres J, Rosales-Mendoza S, Fleury A, Fragoso G, Laclette JP, Sciutto E. Role of Systemic and Nasal Glucocorticoid Treatment in the Regulation of the Inflammatory Response in Patients with SARS-Cov-2 Infection. Arch Med Res. 2021;52:143-150. FI: 2.093 doi: 10.1016/j.arcmed.2020.10.014.
97- Murrieta I, Flores X, Osorio R, Kuschick Feher J, Carrillo-Mezo R, Fleury A (corresponding author). Natural history of extraparenchymal neurocysticercosis. Trans R Soc Trop Med Hyg. 2021 Oct 1;115(10):1218-1225. doi: 10.1093/trstmh/traa174. PMID: 33587139. IF: 2.820
98- Hamamoto Filho PT, Fragoso G, Sciutto E, Fleury A (corresponding autor). Inflammation in neurocysticercosis: clinical relevance and impact on treatment decisions. Expert Rev Anti Infect Ther. 2021 Apr 9:1-16. doi: 10.1080/14787210.2021.1912592. IF: 3.767
99- Beghi E, Michael BD, Solomon T, Westenberg E, Winkler AS; COVID-19 Neuro Research Coalition. Approaches to understanding COVID-19 and its neurological associations. Ann Neurol. 2021 Apr 9;89(6):1059–67. doi: 10.1002/ana.26076. IF: 10.422
100- Toledo A, Orozco-Suárez S, Rosetti M, Maldonado L, Bautista SI, Flores X, Arellano A, Moreno S, Alonso M, Martínez-Juárez IE, Fragoso G, Sciutto E, Fleury A (corresponding autor). Temporal lobe epilepsy: Evaluation of central and systemic immune-inflammatory features associated with drug resistance. Seizure. 2021 Oct;91:447-455. doi: 10.1016/j.seizure.2021.07.028. IF: 3.184
101- Jiménez L, Castro-Nolasco NK, Fleury A, Díaz-Camacho SP, Ochoa-Sánchez A, Landa A. Evaluation of recombinant glutathione transferase 26 kDa, thioredoxin-1, and endophilin B1 of Taenia solium in the diagnosis of human neurocysticercosis. Acta Trop. 2021 Dec 26;227:106294. doi: 10.1016/j.actatropica.2021.106294. IF: 3.112
102- Hernández-González A, González-Bertolín B, Urrea L, Fleury A, Ferrer E, Siles-Lucas M, Tamarozzi F, Perteguer MJ. Multiple-bead assay for the differential serodiagnosis of neglected human cestodiases: Neurocysticercosis and cystic echinococcosis. PLoS Negl Trop Dis. 2022 Jan 14;16(1):e0010109. doi: 10.1371/journal.pntd.0010109. IF: 4.411

Circuito de Posgrado, Ciudad Universitaria
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mdcbq@posgrado.unam.mx