Instituto de Neurobiología. UNAM (IN)
Contacto
Campos de conocimiento
Bioquímica
Neurobiología
Líneas de investigación
-Códigos sinápticos y epigenéticos de la memoria y el aprendizaje
-Dimorfismo sexual en los códigos moleculares que controlan la actividad neuronal
-Neurobiología traslacional: validación de blancos terapéuticos y de códigos moleculares en cerebros humanos
Publicaciones
1) Belloso-Iguerategui A., Zamarbide M., Merino-Galan L., Rodríguez-Chinchilla T., Gago B., Santamaria E., Fernández-Irigoyen J., Cotman C.W., Prieto G.A., Quiroga-Varela A., Rodríguez-Oroz M.C., (2023) Hippocampal synaptic failure is an early event in experimental parkinsonism with subtle cognitive deficit, Brain (en prensa). Factor de impacto = 14.5
2) Lautrup S., Holst C.M., Yde A., Asmussen S., Larsen K., Richner M., Vægter C.B., Prieto G.A., Berchtold N.C., Cotman C.W., Stevnsner T. (2023) The role of aging and BDNF signalling in expression of base excision repair genes in the human brain, Aging cell (en prensa);
Factor de impacto = 7.8
3) Mendoza-Portillo E., Pérez-López A., Alemán-Navarro E., Prieto G.A., Rosenstein Y., Lozano-Nuevo J.J. (2023) Neurological manifestations with jugular vein thrombosis linked to an inflammatory profile as a probable long-COVID sequela, Neuroprotection (en prensa)
Factor de impacto = NA (pending)
4) Prieto G.A.*, Cotman C.W. (2022) Early bioenergetic and autophagy impairments at the Parkinson’s disease synapse, Brain, 145(6):1877-1879.
*Autor de correspondencia
Factor de impacto = 14.5
5) McQuade A., Kang Y., Hasselmann J., Jairaman A., Sotelo A., Coburn M., Shabestari S.K., Chadarevian J.P., Fote G., Tu C.H., Danhash E., Silva J., Martinez E., Cotman C., Prieto G.A., Thomson L.M., Steffan J.S., Smith I., Davtyan H., Cahalan M., Cho H., Blurton-Jones M. (2020) Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease, Nat commun, 11(1):5370.
Factor de impacto = 17.7
DOI: 10.1038s41467-020-19227-5.
6) Rodriguez-Ortiz C.J., Prieto G.A., Martini A.C., Forner S., Trujillo-Estrada L., LaFerla F.M., Baglietto D., Cotman C.W., Kitazawa M. (2020) miR-181a inhibition rescues synaptic plasticity and memory in models of Alzheimer’s disease, Aging cell; 19(3):e13118.
Factor de impacto = 7.8
DOI: 10.1111acel.13118
7) Forner S., Martini A.C., Prieto G.A., Dang C.T., Trujillo-Estrada L., da Cunha C., Andrews E.J., Phan J., Vu J., Levites Y., Cruz P.E., Ager R., Medeiros R., Cotman C.W., Golde T., Baglietto-Vargas D., LaFerla F.M. (2019) Intra- and extracellular amyloid-β overexpression via AAV-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus, Sci Rep; 9, 15936.
Factor de impacto = 4.6
DOI: 10.1038s41598-019-52324-0.
8) Prieto G.A.*, Smith E.D., Tong L., Nguyen M., Cotman C.W. (2019) Inhibition of LTP-induced translation by IL-1β reduces the level of newly synthesized proteins in hippocampal dendrites, ACS Chem Neurosci; 10(3):1197-1203.
Factor de impacto = 5.0
DOI: 10.1021acschemneuro.8b00511
*Autor de correspondencia
9) Prieto G.A.*, Tong L., Smith E.D., Cotman C.W. (2019) TNFα and IL-1 but not IL-18 suppresses hippocampal long-term potentiation directly at the synapse, Neurochem Res; 44(1):49-60.
Factor de impacto = 4.2
DOI:10.1007s11064-018-2517-8
*Autor de correspondencia
10) Berchtold N.C., Prieto G.A., Phelan P., Gillen D.L., Baldi P., Bennett D.A. Buchman A.S. and Cotman C.W. (2019) Hippocampal gene expression patterns linked to late-life physical activity in humans oppose age and AD-related transcriptional decline, Neurobiol Aging; 78:142-154.
Factor de impacto = 5.1
DOI: 10.1016j.neurobiolaging.2019.02.012
11) Trujillo-Estrada L., Nguyen C., Cunha C., Cai L., Forner S., Martini A.C., Ager R.R., Prieto G.A., Cotman C.W., Baglietto-Vargas D., LaFerla F.M. (2019) Tau underlies synaptic and cognitive deficits for type 1, but not type 2 diabetes mouse models, Aging Cell; e12919. doi: 10.1111acel.12919.
Factor de impacto = 7.8
DOI: 10.1111acel.12919.
12) Tong L., Prieto G.A., Cotman C.W. (2018) IL-1β suppresses cLTP-induced surface expression of GluA1 and actin polymerization via ceramide-mediated Src activation, J Neuroinflamm; 15(1):127.
Factor de impacto = 9.6
DOI: 10.1186s12974-018-1158-9
13) Baglietto D., Prieto G.A., Limon A., Forner S., Rodriguez-Ortiz C.J., Ikemura K., Ager R.R., Medeiros R., Trujillo-Estrada L., Martini A.C., Kitazawa M, Davila J.C., Cotman C.W., Gutierrez A., LaFerla F.M. (2018) AMPA signaling and actin cytoskeleton impairments underlie early synaptic dysfunction in a mouse model of Alzheimer’s disease, Aging cell; 6:e12791.
Factor de impacto = 7.8
DOI: 10.1111acel.12791.
