Estudio químico-biológico de metabolitos especializados derivados de microorganismos fúngicos con potencial aplicación en medicina, particularmente para el tratamiento de la diabetes mellitus tipo II (DMTII), e infecciones bacterianas multirresistentes.

Publicaciones

The Value of Universally Available Raw NMR Data for Transparency, Reproducibility, and Integrity in Natural Product Research
McAlpine James B., Chen Shao-Nong, ..... Rivera-Chávez José,...Guido F. Pauli
Natural Products Reports
36, 36-107, 2019

Delitpyrones: α-Pyrone Derivatives from a Freshwater Delitschia sp.
Rivera-Chávez José, El-Elimat Tamam, , Gallagher Jacklyn M., Graff Tyler N., Fournier Jacques, Panigrahi Gati K., Bunch Rick L., Raja Huzefa y Oberlies Nicholas H.
Planta Medica
85, 62-71, 2019

Development and Utilization of a Palladium-Catalyzed Dehydration of Primary Amides To Form Nitriles
Al-Huniti Mohammed H., Rivera-Chávez José, Colón Katsuya L., Stanley Jarrod., Burdette Joanna E., Pearce Cedric C., Oberlies Nicholas H., Croatt Mitchell P.
Organic Letters
20, 19, 6046-6050, 2018

Mycopyranone: A 8,8ˈ-binaphthopyranone with potent anti-MRSA activity from the fungus Phialemoniopsis sp.
Rivera-Chávez José, Caesar Lindsay K., Garcia-Salazar Juan J., Raja Huzefa A., Cech Nadja B., Pearce Cedric J., y Oberlies Nicholas H.
Tetrahedron Letters, Portada de revista
60(8), 594-597, 2019

Prenylated Diresorcinols Inhibit Bacterial Quorum Sensing
Paguigan Noemi D., Rivera-Chávez José, Stempin Justin J., Augustinović Mario, Noras Aleksandra I., Raja Huzefa A., Todd Daniel A., Triplett Kathleen D., Day Cynthia, Figueroa Mario, Hall Pamela R., Cech Nadja B., y Oberlies Nicholas H.
Journal of Natural Products
82(3), 550-558, 2019

Cuautepestalorin, a 7,8-Dihydrochromen-Oxoisochromane Adduct Bearing a Hexacyclic Scaffold from Pestalotiopsis sp. IQ-011
Rivera-Chávez José,* Zacatenco-Abarca Jade, Morales-Jiménez Jesús, Martínez-Aviña Blanca, Hernández-Ortega Simón, y Aguilar-Ramírez Enrique
Organic Letters
21(1), 3558-3562, 2019

Syntaxin 6-mediated Exosome Secretion Regulates Enzalutamide Resistance in Prostate Cancer
Peak Taylor C., Panigrah Gati K., Praharaj Prakash P., Su Yixin, Shi Lihong, Chry Jacqueline, Rivera-Chávez José, Flores-Bocanegra Laura, Singh Ravi, Vander Griend Donald, J., Oberlies Nicholas H., Kerr Bethany A., Hemal Ashok, Bitting Rhonda L. y Deep Gagan
Molecular Carcinogenesis
59(1), 62-72, 2020

Drug Leads from Endophytic Fungi: Lessons Learned via Scaled Production
Graf Tyler N., Kao Diana, Rivera-Chávez José, Gallagher Jacklyn M., Raja Huzefa A., y Oberlies Nicholas H.
Planta Medica
86(13-14), 988-996, 2020

Structural Elucidation of Malonylcommunol and 6β-Hydroxy-trans-communic Acid, Two Undescribed Diterpenes from Salvia cinnabarina. First Examples of Labdane Diterpenoids from a Mexican Salvia Species
Bustos-Brito Celia, Nieto-Camacho Antonio, Hernandez-Ortega Simón, Rivera-Chávez José, Quijano Leovigildo y Esquivel Baldomero
Molecules
25, 2-17, 2020

Dimeric phenalenones from Talaromyces sp. (IQ-313) inhibit hPTP1B1-400: Insights into mechanistic kinetics from in vitro and in silico studies
Jiménez-Arreola Brenda S., Aguilar-Ramírez Enrique, Cano-Sánchez Patricia, Morales-Jiménez Jesús, González-Andrade Martín, Medina-Franco José L., y Rivera-Chávez José*
Bioorganic Chemistry
101, 103893, 2020

Hydroxy-neo-clerodanes and 5,10-seco-neo-clerodanes from Salvia decora
Rivera-Chávez José* Bustos-Brito Celia, Aguilar-Ramírez Enrique, Martínez-Otero Diego, Rosales-Vázquez Luis D., Dorazco González Alejandro y Cano-Sánchez Patricia
Journal of Natural Products
83(7), 2212-2220, 2020

Antinociceptive and anxiolytic-like effects of a neoclerodane diterpene from Salvia semiatrata aerial parts
Ortiz-Mendoza Nancy, Zavala-Ocampo Lizeth M., Martínez Gordillo Martha J., González-Trujano María Eva, Basurto Peña Francisco A., Bazany-Rodríguez Iván J., Rivera-Chávez José Alberto, Dorazco-González Alejandro y Eva Aguirre-Hernández
Pharmaceutical Biology
58(1), 620-629, 2020

Phenethyisoquinoline alkaloids from the leaves of Androcymbium palaestinum
El-Elimat Tamam, Alhawarri Maram B., Rivera-Chávez José, Burdette Joanna E., Czarnecki Austin, Al-Gharaibeh Mohammad, Al-Sharie Ahmed H., Alhusban Ahmed, Alali Feras Q. y Oberlies Nicholas H.
Fitoterapia
146, 104706, 2020

One step partial synthesis of (±)-asperteretone B and related hPTP1B1-400 inhibitors from butyrolactone I
Rivera-Chávez José* Coporo-Blancas Diego y Jesús Morales-Jiménez
Bioorganic and Medicinal Chemistry
28, 24, 115817, 2020

Apoptosis induced by (+)-betulin through NF-ĸB inhibition in MDA-MB-231 breast cancer cells
Anaya-Eugenio Gerardo D., Eggers Nicole A., Ren Yulin, Rivera-Chávez José, Douglas Kinghorn and Carcache de Blanco Esperanza J.
Anticancer Research
40, 6637-6647, 2020

Tetradecanoic acids with anti-virulence properties increase the pathogenicity of Pseudomonas aeruginosa in a murine cutaneous infection model
Juárez-Rodríguez Martha María, Cortes-López Humberto, García-Contreras Rodolfo, González-Pedrajo Bertha, Díaz-Guerrero Miguel A., Martínez-Vázquez Mariano, José Rivera-Chávez, Soto-Hernández Marcos and Castillo-Juárez Israel
Frontiers in Cellular and Infection Microbiology
2021

Clerodane and 5 10-Seco-Clerodane-type diterpenoids from Salvia involucrata
Bustos-Brito Celia, Pérez-Juanchi Diana, Rivera-Chávez José, Hernández-Herrera Alejandro David, Bedolla-García Brenda Y., Zamudio Sergio, Ramírez-Apan, Quijano Leovigildo y Esquivel Baldomero
Journal of Molecular Structure
10.1016/j.molstruc.2021.130367, 2021

Protein tyrosine phosphatase 1B inhibitors from the fungus Malbranchea albolutea
Díaz-Rojas Miriam, Raja Huzefa, González-Andrade Martín, Rivera-Chávez José, Rangel-Grimaldo Manuel, Rivero-Cruz Isabel and Mata Rachel
Phytochemistry
10.1016/j.phytochem.2021.112664, 2021

Absolute configuration and protein tyrosine phosphatase 1B inhibitory activity of xanthoepocin, a dimeric naphtopyrone from Penicillium sp. IQ-429
Martínez-Aldino Ingrid Y., Villaseca-Murillo Martha, Morales-Jiménez Jesús y Rivera-Chávez José*
Bioorganic Chemistry
DOI: 10.1016/j.bioorg.2021.105166

Crystal structures and study of interaction mode of bis-benzimidazole-benzene derivatives with DNA
Valdes-García Josue, Viviano-Posadas Alejandro, Rivera-Chávez José, Ramírez-Apan Teresa, Martínez-Vargas Sergio, Aguirre-Hernández Eva, German-Acacio Juan M., Morales-Morales David y Dorazco-González Alejandro
Journal of Molecular Structure
DOI: 10.1016/j.molstruc.2021.131582

Biological dark matter exploration using data mining for the discovery of antimicrobial natural products
Rivera-Chávez José, Ceapă Corina-Diana y Figueroa Mario
Planta Medica
DOI: 10.1055/a-1795-0562, 2022

Jatrophenediol, a pseudoguaiane sesquiterpenoid from Jatropha dioica rhizomes
Bautista Elihú, Lozano-Gamboa Sarahí, Fragoso-Serrano Mabel, Rivera-Chávez José y Salazar-Olivo Luis A.
Tetrahedron Letters
DOI: 10.1016/j.tetlet.2022.154040

Cytotoxic constituents of Glycosmis ovoidea collected in Vietnam
Blanco-Carcache Peter J., Anaya-Eugenio Gerardo D., Ngoc Ninh Tran, Moore Curtis E., Rivera-Chávez José, Ren Yulin, Soejarto Djaja D., Kinghorn Douglas A
Fitoterapia
DOI: 10.1016/j.fitote.2022.105265, 2022

Synthesis and cytotoxic/antimicrobial screening of 2-alkenylimidazo[1,2-a] pyrimidines
Ramírez-Trinidad Ángel, Carrillo-Jaimes Karol, Rivera-Chávez José, Hernández-Vázquez Eduardo
Medicinal Chemistry Research
32, 144-157, 2023

neo-Clerodane and tiliifolane-type diterpenoids, and other constituents from Salvia pennellii
Sepúlveda-Cuellar Laura, Cárdenas Jorge, Toscano A. Rubén, Rivera-Chávez José, Elihú Bautista, Bedolla-García Brenda Y., Flores Joel
Tetrahedron Letters
20223, 10.1016/j.tetlet.2023.154491

Trachymyrmex septentrionalis ants promote fungus garden hygiene using Trichoderma-derived metabolite cues
Kylea Kathleen E., Puckettb Sara P., Caraballo-Rodríguez Andrés Mauricio, Rivera-Chávez José, Samples Robert M., Earpd Cody E., Raja Huzefa A., Pearce Cedric J., Ernst Madeleine, van der Hooft Justin J.J., Adamsa Madison E., Oberlies Nicholas H., Dorrestein Pieter C., Klassen Jonathan L., Balunas Marcy J.
Proceedings of the National Academy of Sciences (PNAS)
2023, 120, e2219373120, 10.1073/pnas.2219373120

Ants/nest-associated fungi and their specialized metabolites: Diversity, Chemistry, and Bioactivity
Aguilar-Colorado Ángel Sahid, Rivera-Chávez José*
Revista Brasileira de Farmacognosia,
2023, 33, 901–923.

Harnessing the reactivity of duclauxin toward obtaining hPTP1B1-400 inhibitors
Aguilar-Ramírez Enrique, Rivera-Chávez José*, Carlos Fajardo-Hernández, Quezada-Suaste Carlos D., Carreón-Escalante Mario, Reyes-López Valeria, Merlin-Lucas Verenice, Quiroz-García Beatriz
Journal of Medicinal Chemistry
2023, Enviado

Taxonomic and chemical diversity of Mexican mangrove associated ascomycetes to discover new or repositioning bioactive natural products
Martínez-Aldino Ingrid Y., Morales-Jiménez Jesús, Rivera-Chávez José*
Journal of Natural Products
2023, Enviado

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx