Contacto
Campos de conocimiento
Bioquímica
Bioquímica
Fisiología Molecular
Líneas de investigación
Regulación del metabolismo mitocondrial y de colágena, durante la regeneración hepatica y la cirrosis
Identificación de señales metabólicas extra-hepáticas durante la regeneración hepática.
Metabolismo de arginina y otros aminoácidos por eritrocitos de sujetos normales y en aquellos de pacientes con diabetes mellitus tipo 2 o con cirrosis.
Publicaciones
1: Valderrama-Treviño AI, Castell-Rodríguez AE, Hernández-Muñoz R, Vázquez-Torres NA, Macari-Jorge A, Barrera-Mera B, Maciel-Cerda A, Vera-Graziano R, Nuño-Lámbarri N, Montalvo-Javé EE. Development of a biodegradable prosthesis through tissue engineering, for the organ-replacement or substitution of the extrahepatic bile duct.
Ann Hepatol. 2024 Oct 11;30(1):101588. doi:10.1016/j.aohep.2024.101588. FI: 3.20
2: Mata-Martínez E, Ramírez-Ledesma MG, Vázquez-Victorio G, Hernández-Muñoz R, Díaz-Muñoz M, Vázquez-Cuevas FG. Purinergic Signaling in Non-Parenchymal Liver Cells. Int J Mol Sci. 2024 Aug 30;25(17):9447. doi: 10.3390/ijms25179447. FI: 5.60
3: Valderrama-Treviño AI, Castell-Rodríguez AE, Hernández-Muñoz R, Vázquez-Torres NA, Macari-Jorge A, Barrera-Mera B, Maciel-Cerda A, Vera-Graziano R, Nuño-Lámbarri N, Montalvo-Javé EE. Development of a biodegradable prosthesis through tissue engineering, for the organ-replacement or substitution of the extrahepatic bile duct.
Ann Hepatol. 2024 Sep-Oct;29(5):101530. doi:10.1016/j.aohep.2024.101530. FI: 3.20
4: González-Alfonso WL, Petrosyan P, Del Razo LM, Sánchez-Peña LC, Tapia-Rodríguez M, Hernández-Muñoz R, Gonsebatt ME. Chronic Exposure to Arsenic and Fluoride Starting at Gestation Alters Liver Mitochondrial Protein Expression and Induces Early Onset of Liver Fibrosis in Male Mouse Offspring.
Biol Trace Elem Res. 2024 Apr 27. doi: 10.1007/s12011-024-04198-1. FI: 3.40
5: Contreras-Zentella ML, Alatriste-Contreras MG, Suárez-Cuenca JA, Hernández-Muñoz R. Gender effect of glucose, insulin/glucagon ratio, lipids, and nitrogen-metabolites on serum HGF and EGF levels in patients with diabetes type 2.
Front Mol Biosci. 2024 Apr 9;11:1362305. doi: 10.3389/fmolb.2024.1362305. FI: 4.77
6: Hernández-Espinosa LC, Hernández-Muñoz R. Blood flow-bearing physical forces, endothelial glycocalyx, and liver enzyme mobilization: A hypothesis.
J Gen Physiol. 2024 Mar 4;156(3):e202313462. doi: 10.1085/jgp.202313462. FI: 3.30
7: Suárez-Cuenca JA, Domínguez-Pérez GA, Hernández-Muñóz RE, Hernández-Patricio A, Vera-Gómez E, Gutiérrez-Buendía JA, Salamanca-García M, Montoya-Ramírez J, Gaytán-Fuentes OF, Aranda-Rodríguez C, Rojas-Noverón AR, García S, Mondragón-Terán P. Nonalcoholic Fatty Liver Disease Severity Is Related to Plasma Pro-Oxidative Biomarkers Rather Than Liver Tissue-Measured Nitrogen Metabolism Biomarkers in Population with Obesity and Metabolic Syndrome.
Metab Syndr Relat Disord. 2023 Mar;21(2):115-121. doi: 10.1089/met.2022.0007. FI: 2.10
8: Melchor-López A, Suárez-Cuenca JA, Banderas-Lares DZ, De la Peña-Sosa G, Salamanca-García M, Vera-Gómez E, Hernández-Patricio A, Gutiérrez-Buendía JA, Zamora-Alemán CR, Alcaráz-Estrada SL, Ortiz-Fernández M, Montoya-Ramírez J, Felipe Gaytán-Fuentes O, Escamilla-Tilch M, Pineda-Juárez JA, Antonio Téllez-González M, Rodríguez-Arellano ME, Contreras-Ramos A, Hernández-Muñoz RE, Gutiérrez-Salinas J, García S, Mondragón-Terán P. The metabolic phenotype of the patient influences the reduction in carotid intima-media thickness achieved following metabolic surgery.
J Int Med Res. 2022 Nov;50(11):3000605221137475. doi: 10.1177/030006052. FI: 1.76
9: Contreras-Zentella ML, Villalobos-García D, Hernández-Muñoz R. Ethanol Metabolism in the Liver, the Induction of Oxidant Stress, and the Antioxidant Defense System.
Antioxidants (Basel). 2022 Jun 26;11(7):1258. doi:10.3390/antiox11071258. FI: 7.00
10: Díaz-Muñoz M, Hernández-Muñoz R, Butanda-Ochoa A. Structure-activity features of purines and their receptors: implications in cell physiopathology.
Mol Biomed. 2022 Jan 26;3(1):5. doi: 10.1186/s43556-022-00068-1. FI: 6.30
11: Contreras-Zentella ML, Hernández-Muñoz R. Possible Gender Influence in the Mechanisms Underlying the Oxidative Stress, Inflammatory Response, and the Metabolic Alterations in Patients with Obesity and/or Type 2 Diabetes.
Antioxidants (Basel). 2021 Oct 29;10(11):1729. doi: 10.3390/antiox10111729. FI: 7.00
12: Vázquez-Martínez O, Díaz-Muñoz M, López-Barrera F, Hernández-Muñoz R. Mitochondrial Oxidation of the Cytoplasmic Reducing Equivalents at the Onset of Oxidant Stress in the Isoproterenol-Induced Rat Myocardial Infarction.
Antioxidants (Basel). 2021 Sep 11;10(9):1444. doi: 10.3390/antiox10091444. FI: 7.00
13: Martiñón-Gutiérrez G, Luna-Castro M, Hernández-Muñoz R. Role of insulin/glucagon ratio and cell redox state in the hyperglycaemia induced by exposure to a 60-Hz magnetic field in rats.
Sci Rep. 2021 Jun 3;11(1):11666. doi: 10.1038/s41598-021-91228-w. FI: 3.80
14: Melchor-López A, Suárez-Cuenca JA, Banderas-Lares DZ, Peña-Sosa G, Salamanca-García M, Vera-Gómez E, Hernández-Patricio A, Gutiérrez-Buendía JA, Zamora-Alemán CR, Alcaráz-Estrada SL, Ortiz-Fernández M, Montoya-Ramírez J, Gaytán-Fuentes OF, Pérez-Cabeza de Vaca R, Escamilla-Tilch M, Pineda-Juárez JA, Téllez-González MA, Mondragón-Terán P, Rodríguez-Arellano ME, Contreras-Ramos A, García S, Hernández-Muñoz RE. Identification of adipose tissue-related predictors of the reduction in cardiovascular risk induced by metabolic surgery.
J Int Med Res. 2021 May;49(5):3000605211012569. doi: 10.1177/03000605211. FI: 1.76
15: Villalobos-García D, Ayhllon-Osorio CA, Hernández-Muñoz R. The fructose-dependent acceleration of ethanol metabolism.
Biochem Pharmacol. 2021 Jun;188:114498. doi: 10.1016/j.bcp.2021.114498. FI: 5.60
16: Contreras-Zentella ML, Sánchez-Sevilla L, Suárez-Cuenca JA, Olguín-Martínez M, Alatriste-Contreras MG, García-García N, Orozco L, Hernández-Muñoz R. The role of oxidant stress and gender in the erythrocyte arginine metabolism and ammonia management in patients with type 2 diabetes.
PLoS One. 2019 Jul 17;14(7):e0219481. doi: 10.1371/journal.pone.0219481. FI: 3.30
17: Villalobos-García D, Hernández-Muñoz R. Lactate-stimulated ethanol oxidation: Revisiting an old hypothesis.
Biochem Pharmacol. 2019 Jun;164:283-288. doi: 10.1016/j.bcp.2019.04.012. FI: 5.60
18: Hernández-Muñoz R, Lucinda Contreras-Zentella M. Involvement of cell oxidant status and redox state in the increased non-enzymatic ethanol oxidation by the regenerating rat liver.
Biochem Pharmacol. 2019 Mar;161:63-72. doi: 10.1016/j.bcp.2019.01.003. FI: 5.60