La autofagia como mecanismo regulador del metabolismo energético y su relación con enfermedades metabólicas, como la diabetes y el síndrome metabólico.

Publicaciones

1. Ortega-Cuellar D, González-Sánchez I, Piñón-Zárate G, Cerbón MA, De la Rosa V, Franco-Juárez Y, Castell-Rodríguez A, Islas LD, Coronel-Cruz C. Protector Role of Cx30.2 in Pancreatic β-Cell against Glucotoxicity-Induced Apoptosis. Biology 2024. IF: 3.6

2. Aguilera-Méndez A, Figueroa-Fierros I, Ruiz-Pérez X, Godínez-Hernández D, Saavedra-Molina A, Rios-Chavez P, Villafaña S, Boone-Villa D, Ortega-Cuellar D, Gauthereau-Torres MY, Nieto-Aguilar R, Palomera-Sanchez Z. The Beneficial Effects of Prenatal Biotin Supplementation in a Rat Model of Intrauterine Caloric Restriction to Prevent Cardiometabolic Risk in Adult Female Offspring. Int. J. Mol. Sci. 2024. IF: 4.9

3. Gutiérrez-Cardona JY, Calderón-Jaimes E, Ortega-Cuellar D, Sánchez-Carrillo A, Castillo-Rodríguez RA, Canseco-Ávila LM, Rocha-Ramírez LM, Martínez-Rosas V, Gómez-Manzo S, Hernández-Ochoa B. Imidazole Carbamates as a Promising Alternative for Treating Trichomoniasis: In Vitro Effects on the Growth and Gene Expression of Trichomonas vaginalis. Int J Mol Sci. 2024. IF: 4.9

4. Gutiérrez-Cardona JY, Calderón-Jaimes E, Ortega-Cuellar D, Sánchez-Carrillo A, Castillo-Rodríguez RA, Canseco-Ávila LM, Rocha-Ramírez LM, Martínez-Rosas V, Gómez-Manzo S, Hernández-Ochoa B. Effect of Trichomonacide 6-Nitro-1H-benzimidazole Derivative Compounds on Expression Level of Metabolic Genes in Trichomonas vaginalis. Int J Mol Sci. 2024. IF: 4.9

5. Morales-Luna L, Vázquez-Bautista M, Martínez-Rosas V, Rojas-Alarcón MA, Ortega-Cuellar D, González-Valdez A, Pérez de la Cruz V, Arreguin-Espinosa R, Rodríguez-Bustamante E, Rodríguez-Flores E, Hernández-Ochoa B, Gómez-Manzo S. Fused Enzyme Glucose-6-Phosphate Dehydrogenase::6-Phosphogluconolactonase (G6PD::6PGL) as a Potential Drug Target in Giardia lamblia, Trichomonas vaginalis, and Plasmodium falciparum. Microorganisms. 2024. IF: 4.1

6. Hernández-Ochoa B, Ortega-Cuellar D, González-Valdez A, Martínez-Rosas V, Morales-Luna L, Rojas-Alarcón MA, Vázquez-Bautista M, Arreguin-Espinosa R, Pérez de la Cruz V, Castillo-Rodríguez RA, Canseco-Ávila LM, Vidal-Limón A, Gómez-Manzo S. An Overall View of the Functional and Structural Characterization of Glucose-6-Phosphate Dehydrogenase Variants in the Mexican Population. Int J Mol Sci. 2023. IF: 5.6

7. Martínez-Rosas V, Hernández-Ochoa B, Morales-Luna L, Ortega-Cuellar D, González-Valdez A, Arreguin-Espinosa R, Rufino-González Y, Calderón-Jaimes E, Castillo-Rodríguez RA, Wong-Baeza C, Baeza-Ramírez I, Pérez de la Cruz V, Vidal-Limón A, Gómez-Manzo S. Nitazoxanide Inhibits the Bifunctional Enzyme GlG6PD::6PGL of Giardia lamblia: Biochemical and In Silico Characterization of a New Druggable Target. Int J Mol Sci. 2023. IF: 5.6

8. Mendoza-Torreblanca JG, Cárdenas-Rodríguez N, Carro-Rodríguez J, Contreras-García IJ, Garciadiego-Cázares D, Ortega-Cuellar D, Martínez-López V, Alfaro-Rodríguez A, Evia-Ramírez AN, Ignacio-Mejía I, Vargas-Hernández MA, Bandala C. Antiangiogenic Effect of Dopamine and Dopaminergic Agonists as an Adjuvant Therapeutic Option in the Treatment of Cancer, Endometriosis, and Osteoarthritis. Int J Mol Sci. 2023. IF: 5.6

9. Hernández-Ochoa B, Martínez-Rosas V, Morales-Luna L, Calderón-Jaimes E, Rocha-Ramírez LM, Ortega-Cuellar D, Rufino-González Y, González-Valdez A, Arreguin-Espinosa R, Enríquez-Flores S, Castillo-Rodríguez RA, Cárdenas-Rodríguez N, Wong-Baeza C, Baeza-Ramírez I, Gómez-Manzo S. Pyridyl Methylsulfinyl Benzimidazole Derivatives as Promising Agents against Giardia lamblia and Trichomonas vaginalis. Molecules. 2022. IF: 4.9

10. Morales-Luna L, Hernández-Ochoa B, Martínez-Rosas V, Navarrete-Vázquez G, Ortega-Cuellar D, Rufino-González Y, González-Valdez A, Arreguin-Espinosa R, Franco-Vásquez AM, Pérez de la Cruz V, Enríquez-Flores S, Martínez-Conde C, Canseco-Ávila LM, Gómez-Chávez F, Gómez-Manzo S. Giardia lamblia G6PD::6PGL Fused Protein Inhibitors Decrease Trophozoite Viability: A New Alternative against Giardiasis. Int J Mol Sci. 2022. IF: 6.2

11. Franco-Juárez B, Coronel-Cruz C, Hernández-Ochoa B, Gómez-Manzo S, Cárdenas-Rodríguez N, Arreguin-Espinosa R, Bandala C, Canseco-Ávila LM, Ortega-Cuellar D. TFEB; Beyond Its Role as an Autophagy and Lysosomes Regulator. Cells. 2022. IF: 7.6

12. Ortiz-Ramírez P, Hernández-Ochoa B, Ortega-Cuellar D, González-Valdez A, Martínez-Rosas V, Morales-Luna L, Arreguin-Espinosa R, Rosa Castillo-Rodríguez RA, Canseco-Ávila LM, Cárdenas-Rodríguez N, Pérez de la Cruz V, Montiel-González AM, Gómez-Chávez F, Gómez Manzo S. Biochemical and Kinetic Characterization of the Glucose-6-Phosphate Dehydrogenase from Helicobacter pylori Strain 29CaP. Microorganisms, 2022. IF: 4.9

13. Hernández-Ochoa B, Ortega-Cuellar D, González-Valdez A, Cárdenas-Rodríguez N, Mendoza-Torreblanca JG, Contreras-García IJ, Pichardo-Macías LA, Bandala C, Gómez-Manzo S. COVID-19 in G6PD-deficient patients, oxidative stress, and neuropathology. Curr Top Med Chem 2022. IF: 3.5

14. Cortés-Algara A, Cárdenas-Rodríguez N, Reyes Long S, Ortega-Cuellar D, Ruz-Barros R, Mondragón-Teran P, Escamilla-Tilch M, Correa-Basurto J, Lara-Padilla E, Alfaro-Rodriguez A, Cortes-Altamirano JL, Bandala C. Effect of Norelgestromin and Ethinylestradiol in Transdermal Patches on the Clinical Outcomes and Biochemical Parameters of COVID-19 Patients: A Clinical Trial Pilot Study. Pharmaceuticals (Basel), 2022. IF: 5.2

15. Franco-Juarez B, Gómez Manzo S, Hernández Ochoa B, Cárdenas-Rodríguez N, Arreguin-Espinosa r, Pérez de la Cruz V and Ortega-Cuellar D. Effects of High Dietary Carbohydrate and Lipid Intake on the Lifespan of C. elegans. Cells. 2021. IF: 6.6

16. Morales-Luna L, González Valdez A, Hernández Ochoa B, Arreguin-Espinosa R, Ortega-Cuellar D, Castillo-Rodríguez RA, Martínez-Rosas V, Cárdenas-Rodríguez N, Enríquez-Flores S, Canseco-Ávila IM, Cruz VP, Gómez-Chávez f, Gómez Manzo S. Glucose-6-Phosphate Dehydrogenase::6-Phosphogluconolactonase from the Parasite Giardia lamblia. A Molecular and Biochemical Perspective of a Fused Enzyme. Microorganisms. 2021. IF: 4.1

17. Ramírez-nava EJ, Hernández Ochoa B, Navarrete-Vázquez G, Arreguín-Espinosa R, Ortega-Cuellar D, González Valdez D, Martínez-Rosas V, Morales-Luna L, Martínez-Miranda J, Sierra-Palacios E, Rocha-Ramírez IM, de Franceschi L, Marcial-Quino J, Gómez Manzo S. Novel inhibitors of human glucose-6-phosphate dehydrogenase (HsG6PD) affect the activity and stability of the protein. Biochim Biophys Acta Gen Subj. 2021. IF: 3.9.

18. Morales-Luna L, Hernández-Ochoa B, Ramírez-Nava EJ, Martínez-Rosas V, Ortiz-Ramírez P, Fernández-Rosario F, González-Valdez A, Cárdenas-Rodríguez N, Serrano-Posada H, Centeno-Leija S, Arreguin-Espinosa R, Cuevas-Cruz M, Ortega-Cuellar D, Pérez de la Cruz V, Rocha-Ramírez LM, Sierra-Palacios E, Castillo-Rodríguez RA, Vega-García V, Rufino-González Y, Marcial-Quino J, Gómez-Manzo S. Characterizing the Fused TvG6PD::6PGL Protein from the Protozoan Trichomonas vaginalis, and Effects of the NADP+ Molecule on Enzyme Stability. Int J Mol Sci. 2020. IF: 4.5

19. Martínez-Rosas V, Juárez-Cruz MV, Ramírez-Nava EJ, Hernández-Ochoa B, Morales-Luna L, González-Valdez A, Serrano-Posada H, Cárdenas-Rodríguez N, Ortiz-Ramírez P, Centeno-Leija S, Arreguin-Espinosa R, Cuevas-Cruz M, Ortega-Cuellar D, Pérez de la Cruz V, Rocha-Ramírez LM, Sierra-Palacios E, Castillo-Rodríguez RA, Baeza-Ramírez I, Marcial-Quino J, Gómez-Manzo S. Effects of Single and Double Mutants in Human Glucose-6-Phosphate Dehydrogenase Variants Present in the Mexican Population: Biochemical and Structural Analysis.. Int J Mol Sci. 2020. IF 4.5.

20. Cárdenas-Rodríguez N, Carmona-Aparicio L, Pérez-Lozano DL, Ortega-Cuellar D, Gómez-Manzo S, Ignacio-Mejía I. Genetic variations associated with pharmacoresistant epilepsy. Mol Med Rep. 2020. IF 3.4

Circuito de Posgrado, Ciudad Universitaria
Alcaldía Coyoacán, C.P. 04510, México, CDMX

55 5623 7006
mdcbq@posgrado.unam.mx