Tutores

Campos de conocimiento

Estudios bioquímicos y biofísicos de proteínas parálogas involucradas en la síntesis de ribosomas o el proceso de traducción y su relación con heterogeneidad ribosomal.

Caracterización estructural y funcional del sistema de secreción tipo VII de Mycobacterium tuberculosis y su relación con la patogenicidad de la bacteria.

1. Tavabi, A. H., Rosi, P., Ravelli, R. B. G., Gijsbers, A., Rotunno, E., Guner, T., Zhang, Y., Roncaglia, A., Belsito, L., Pozzi, G., Denneulin, T., Gazzadi, G. C., Ghosh, M., Nijland, R., Frabboni, S., Peters, P. J., Karimi, E., Tiemeijer, P., Dunin-Borkowski, R. E., and Grillo, V. (2024) Symmetry and planar chirality measured with a log-polar transformation in a transmission electron microscope. Physical Review Applied. https://journals.aps.org/prapplied/abstract/10.1103/PhysRevApplied.22.014083
Impact factor: 3.7

2. Tzfadia, O., Gijsbers A., Vujkovic, A., Snobre, J., Vargas, R., Dewaele, K., Meehan, C.J., Farhat, M., Hakke, S., Peters, Jong, B.C. , Siroy, A., and Ravelli, R.B.G. (2024) Single nucleotide variation catalog from clinical isolates mapped on tertiary and quaternary structures of ESX-1-related proteins reveals critical regions as putative Mtb therapeutic targets. Microbiology Spectrum. https://doi.org/10.1128/spectrum.03816-23.
Impact factor: 3.7

3. Lozano-Andrés, E., Enciso-Martínez, A., Gijsbers, A., Libregts, S.F.W.M., Pinheiro, C., van Niel, G., Hendrix, A., Peters, P.J., Otto, C., Arkesteijn, G.J.A. and Wauben, M.H.M (2023) The presence of lipoprotein particles distorts the analysis and characterization of single extracellular vesicles. Journal of Extracellular Vesicles. https://doi.org/10.1002/jev2.12376.
Impact factor: 15.5

4. Gijsbers, A., et al. (2023) The crystal structure of the EspB-EspK virulence factor-chaperone complex suggests an additional type VII secretion mechanism in M. tuberculosis. Journal of Biological Chemistry. https://doi.org/10.1016/j.jbc.2022.102761.
Impact factor: 4.0

5. Gijsbers, A. et al. (2021) Mycobacterium tuberculosis ferritin: a suitable workhorse protein for cryo-EM development. Acta Crystallographica D (Structural Biology). https://doi.org/10.1107/S2059798321007233.
Impact factor: 5.2

6. Gijsbers, A. et al. (2021) Priming mycobacterial ESX-secreted protein B to form a channel-like structure. Current Research in Structural Biology. https://doi.org/10.1016/j.crstbi.2021.06.001.
Impact factor: 2.7

7. Gijsbers, A. et al. (2021) Structural analysis of the partially disordered protein EspK from Mycobacterium tuberculosis. Crystals. https://doi.org/10.3390/cryst11010018.
Impact factor: 2.4

8. Ravelli, R.B.G., Nijpels, F.J.T., Henderikx, R.J.M., Weissenberger, G., Thewessem, S., Gijsbers, A. et al. (2020) Cryo-EM structures from sub-nl volumes using pin-printing and jet vitrification. Nature Communications. https://doi.org/10.1038/s41467-020-16392-5.
Impact factor: 14.7

9. Delre, P., Alberga, D., Gijsbers, A. et al. (2019) Exploring the role of elongation Factor-Like 1 (EFL1) in Shwachman-Diamond syndrome through molecular dynamics. Journal of Biomolecular Structure and Dynamics. https://doi.org/10.1080/07391102.2019.1704883.
Impact factor: 2.7